UW-Madison, Biostatistics & Medical Informatics


	Paul Rathouz
	Professor and Department Chair, Biostatistics & Medical Informatics
	PhD, Biostatistics, Johns Hopkins University, 1997

	K6/446a Clinical Science Center (CSC) 600 Highland Ave Madison, WI 53792-4675 Phone: 608-263-1706 FAX: 608-263-1059 Email:

	Paul Rathouz's webpage



Research Interests
Professor Rathouz's areas of methodological interests include missing data in models for highly stratified or longitudinal data, generalized linear models, methods for behavior genetic designs and outcome-dependent sampling. Most of his current applied statistical work is in the areas of developmental psychopathology, epidemiologic sleep research, and arsenic exposure studies.

Selected Publications
Biostatistical Methodology
Liang K-Y, Rathouz PJ, (1999). Hypothesis testing under mixture models: Application to genetic linkage analysis. Biometrics 55, 65--74. PubMed. Rathouz PJ, Liang K-Y. (1999). Reducing sensitivity to nuisance parameters in semiparametric models: A quasiscore method. Biometrika 86, 857--869. Technical Report. Rathouz PJ, Liang K-Y. (2001). Locally ancillary quasiscore models for errors-in-covariates. Journal of the American Statistical Association 96, 1004--1013. Preprint. Rathouz PJ, Satten GA, Carroll RJ. (2002). Semiparametric inference in matched case-control studies with missing covariate data. Biometrika 89, 905--916. Technical report. Preisser, JS, Lohman, KK, Rathouz PJ , (2002). Performance of weighted estimating equations for longitudinal binary data with dropouts missing at random. Statistics in Medicine 21, 3035--3054. PubMed. Allen A, Rathouz PJ, Satten GA. (2003). Informative missingness in genetic association studies: case-parent designs. American Journal of Human Genetics 72, 671--680. PubMed. Rathouz PJ, (2003). Likelihood methods for missing covariate data in highly stratified studies. Journal of the Royal Statistical Society, Series B, 65, 711--723. Preprint. Rathouz PJ, (2004). Fixed effects models for longitudinal binary data with dropouts missing at random. Statistica Sinica 14, 696--988. Technical report. Rathouz PJ, (2007). Identifiability assumptions for missing covariate data in failure time regression models. Biostatistics, 8, 345--356. PubMed. Article link. Dignam JJ, Wieand K, Rathouz PJ, (2007). A missing data approach to semi-competing risks problems. Statistics in Medicine, 26, 837--856. PubMed. Mukherjee B, Ahn J, Liu I, Rathouz PJ, Sánchez BN. (2008). Fitting stratified proportional odds models by amalgamating conditional likelihoods. Statistics in Medicine, 27, 4950--4971. PubMed. Rathouz PJ, Gao L. (2009). Generalized linear models with unspecified reference distribution. Biostatistics, 10, 205--218. PubMed. Article link. Forester JD, Im H-K, Rathouz PJ. Accounting for animal movement in estimation of resource selection functions: Sampling and data analysis. To appear in Ecology. Perin J, Preisser JS, Rathouz PJ. Semi-parametric efficient estimation for incomplete longitudinal binary data with application to smoking trends. Accepted to Journal of the American Statistical Associaion, Applications and Case Studies. Schildcrout JS, Rathouz PJ. Longitudinal studies of binary response data following case-control and stratified case-control sampling: Design and analysis. Revised for Biometrics. Accompanying software.
Developmental Psychopathology and Behavior Genetics
Lauderdale DS, Rathouz PJ, (1999). Evidence of environmental suppression of familial resemblance: Height among U.S. Civil War brothers. Annals of Human Biology 26, 413--426. PubMed. D'Onofrio BM, Van Hulle CA, Waldman ID, Rodgers JL, Rathouz PJ, Lahey BB. (2007). Causal inferences regarding prenatal alcohol exposure and childhood externalizing problems. Archives of General Psychiatry, 64, 1296--1304. PubMed. Rathouz PJ, Van Hulle CA, Rodgers JL, Waldman ID, Lahey BB. (2008). Speci?cation, testing, and interpretation of gene-by-measured-environment interaction models in the presence of gene-environment correlation. Behavior Genetics, 38, 301--315. PubMed. Scripts and supplementary technical materials. Lahey BB, Rathouz PJ, Van Hulle C, Urbano RC, Krueger RF, Applegate B, Garriock HA, Chapman DA, Waldman ID. (2008). Testing structural models of DSM-IV symptoms of common forms of child and adolescent psychopathology. Journal of Abnormal Child Psychology, 36, 187--206. PubMed. Lahey BB, Van Hulle CA, Rathouz PJ, Rodgers JL, D'Onofrio BM, Waldman ID. (2009). Are oppositional-defiant and hyperactive-inattentive symptoms developmental precursors to conduct problems in late childhood?: Genetic and environmental links. Journal of Abnormal Child Psychology, 37, 45--58. PubMed.
Sleep Research
Lauderdale DS, Knutson KL, Yan LJL, Rathouz PJ, Hulley SB, Sidney S, Liu K. (2006). Objectively measured sleep characteristics among early-middle-aged adults - The CARDIA study. American Journal of Epidemiology, 164, 5--16. PubMed. Knutson KL, Rathouz PJ, Yan LJL, Liu K, Lauderdale DS. (2007). Intra-individual daily and yearly variability in actigraphically recorded sleep measures: the CARDIA study. Sleep, 30, 793--796. PubMed. Lauderdale DS, Knutsen KL, Yan LL, Liu K, Rathouz PJ, (2008). Self-reported and measured sleep duration: how similar are they? The CARDIA Sleep Study. Epidemiology, 19, 838--845. PubMed. King CR, Knutsen KL, Rathouz PJ, Sidney S, Liu K, Lauderdale DS. (2008). Short Sleep Duration and Incident Coronary Artery Calcification. Journal of the American Medical Association, 300, 2859--2866. PubMed.
Health Econometrics
Basu A, Rathouz PJ, (2005). Estimating marginal and incremental effects on health outcomes using flexible link and variance function models. Biostatistics 6, 93--109. PubMed. Basu A, Arondekar BV, Rathouz PJ, (2006). Scale of interest versus scale of estimation: Comparing alternative estimators for the incremental costs of a comorbidity. Health Economics, 15, 1091--1107. PubMed. Terza JV, Basu A, Rathouz PJ, (2008). Two-stage residual inclusion estimation: Addressing endogeneity in health econometric modeling. Journal of Health Economics, 27, 531--543. PubMed. Rathouz' listed on PubMed

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