UW Biiostatistics & Medical Informatics UW Biostatistics & Medical Informatics UW Madison UW Biostatistics & Medical Informatics Site Map
UW School of Medicine and Public Health UW Madison


 

 


Other Seminar Series

Seminars

General Departmental Seminar Series

Meta-Analysis of High-Throughput Genomic Data

Debashis Ghosh, PhD,
Department of Biostatistics
University of Michigan

November 12, 2004, 12 - 1 pm in room 1210 Medical Sciences Center (1300 University Ave.)

ABSTRACT

An increasing number of studies have profiled tumor specimens using distinct microarray platforms and analysis techniques. With the accumulating amount of microarray data, one of the most challenging tasks is to develop robust statistical models to integrate the findings. In this talk, we outline the issues associated with combining different genomic datasets. We discuss a two-stage approach for meta-analysis of data from microarrays using a mixture model- based data transformation technique. The methods are applied to validate and integrate independent findings from four microarray studies in breast cancer. If time permits, we will also discuss some recent work in studying false discovery rate estimation procedures under dependence.

Return to seminar list

 

Internal Use | Site Map | Search |
Overview | People | Training | Research | Seminars | Employment | Links |
Biostatistics Program | Clinical Trials Program | Medical Informatics Program | Biomedical Computing |

Copyright © 2006 The Board of Regents of the
University of Wisconsin System

 

UW Madison UW School of Medicine and Public Health