Richard J. Chappell

Professor, Department of Biostatistics & Medical Informatics
and Department of Statistics

Ph.D., 1990, University of Chicago

K6/430 CSC
600 Highland Ave.
Madison, WI 53792-4675

Phone: 608-263-5572
Fax: 608-263-5579
E-mail: chappell at biostat dot wisc dot edu

Research Interests

My principle interests lie in the analysis and design of clinical trials, link estimation in generalized linear models, bivariate and nonparametric survival analysis, and models in radiobiology.

Selected Publications

Acosta D, Chappell R: "Cardiotoxicity of diazepam in cultured heart cells". Toxicology 8(3):311-317, 1977 (Dec).

Michelassi F, Block G, Vanucci L, Montag A, Chappell R: "Five to twenty-one year follow-up and analysis of 250 patients with rectal adenocarcinoma". Journal of the American Surgical Association 208:389-398, 1988. Selected for inclusion in the 1988 Yearbook of Surgery.

Chappell R: "Fitting bent lines to data, with applications to allometry". J Theoretical Biology 138:235-256, 1989.

Chappell R: "Sampling design of multiwave studies with an application to the Massachusetts Health Care Panel Study". Statistics in Medicine 10(12):1945-1991, 1991.

Chappell R: "A note on linear rank tests and Gill and Schumacher's tests of proportionality". Biometrika 79:199-201,1992.

Chappell R, Branch L: "The Goldilocks dilemma in survey design and its solution". Journal of Clinical Epidemiology,46:309-312, 1993.

Chappell R: "Presenting the coefficients of the linear quadratic equation for clinical use". International Journal of Radiation Oncology, Biology, and Physics, 29:191-193, 1994.

Lee AWM, Chan DKK, Fowler JF, Poon YF, Law SCK, Foo W, Tung SY, Cheung FK, Ho JHC, and Chapell R. "T1 Nasopharyngeal Carcinoma: the Effect of Waiting Time on Tumor Control." The International Journal of Radiation Oncology, Biology, and Physics. Vol. 20 (1994), pp. 1111-1117.

Chappell R, Nondahl D, Fowler JF: "Further analysis of the radiobiological parameters from the first and second British Institute of Radiology randomized studies of larynx/pharynx radiotherapy". International Journal of Radiation Oncology, Biology, and Physics 33:509-518, 1995.

Orzack S, Chappell R: "Designing an experiment to estimate brood ratio inheritance". Biometrics 51:822-830, 1995.

Chappell R, Nondahl D, Fowler JF: "Modeling dose and local control in radiotherapy". Journal of the American Statistical Association 90:829-838, 1995.

Newton M, Czado C, Chappell R: "Semiparametric Bayesian link estimation for binary regression". Journal of the American Statistical Association. 91:142-153, 1996.

Lee AWM, Foo W, Law SCK, Poon YF, Sze WM, O SK, Tung SY, Chappell R, Lau WH, Ho JHC. Recurrent nasopharyngeal carcinoma: the puzzles of long latency. The International Journal of Radiation Biology Oncology Physics. 44:149-156, 1999.

Cheung YK, Chappell R. Sequential designs for phase I clinical trials with late-onset toxicities. Biometrics. 56:1177-1182, 2000.

Fowler J, Chappell R, Ritter M. Is alpha / beta for prostate tumors really low? A referred letter in International Journal of Radiation Oncology Biology Physics. Vol 53 (2002), p. 1395.

Cheung YK, and Chapell R. "A Simple technique to evaluate model sensitivity in the continual reassessment method." Biometrics. Vol 58 (2002), pp.671-674.

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Courses

Fall 2007 Statistics 541 Introduction to Biostatistics

Statistics 541, Introduction to Biostatistical Methods (many semesters).

Statistics 641, Statistical Methods for Clinical Trials (many semesters, including Fall 2002).

Statistics 642, Statistical Methods for Epidemiologic Research (Spring 2001).

Statistics 851, Generalized Linear Models (many semesters).

Statistics 998, Statistical Consulting (Fall 2001).