Mark Craven's Research Group
My research is focused on developing and applying machine-learning
algorithms in the context of biomedical problems.
Current projects in my group are addressing such tasks as:
- identifying gene-regulatory elements in genomic sequences,
- uncovering and modeling networks of interactions among
genes and other cellular components,
- modeling, classifying and aligning temporal
gene-expression responses induced by toxicants,
- annotating high-throughput biological experiments,
- extracting structured information from the scientific literature.
The machine-learning issues that we are researching include:
- Learning expressive models for sequence data, including
models that represent overlapping elements, complex
configurations of sequence elements, and real-valued outputs
conditioned on sequence features.
- Learning in problem domains where most instances are
either unlabeled or labeled at a coarse level of granularity.
We are developing novel methods for active learning and
multiple-instance learning.
- Learning models that represent high-dimensional,
sparsely-sampled time series.
Current Postdocs
Current PhD Students
Graduated PhD Students
- Dave Andrzejewski, PhD 2010 (co-advised by Xiaojin Zhu)
thesis: Incorporating Domain Knowledge in Latent Topic Models
current position: Postdoctoral Researcher, Lawrence Livermore National Laboratory
- Joe Bockhorst, PhD 2005
thesis: Machine Learning Methods for Discovering Regulatory Elements in Bacterial Genomes
current position: Assistant Professor, University of Wisconsin-Milwaukee
- Keith Noto, PhD 2007
thesis: Learning Expressive Computational Models of Gene Regulatory Sequences and Responses
current position: Postdoctoral Researcher, Tufts University
- Yue Pan, PhD 2009
thesis: Inferring
Mechanism-Based Gene Regulatory Network Models from Expression and Sequence Data
current position: Research Scientist, Facebook
- Soumya Ray,
PhD 2005 (co-advised by David Page)
thesis: Learning from Data with Complex Interactions and Ambiguous Labels
current position: Assistant Professor, Case Western Reserve University
- Burr Settles,
PhD 2008
thesis: Curious Machines: Active Learning with Structured Instances
current position: Postdoctoral Fellow, Carnegie Mellon University
- Adam Smith,
PhD 2009
thesis: Classification and Alignment of Gene-Expression Time-Series Data
current position: Postdoctoral Researcher, Oregon Health Sciences University
Last modified: Wed Dec 17 22:17:14 CST 2008