Both uracilless death and papillae formation during uracil starvation are markedly more extensive in rad6-1 than in RAD6 strains. Osmotic stabilization with 1 mol/L glucitol improves the growth of rad6-1 polyauxotrophic strains in supplemented minimal medium and partially suppresses both the uracilless death and cannibalistic growth of papillae on colonies.