Computational biology research at the University of Wisconsin-Madison and the Morgridge Institute for Research
Our lab's research involves designing algorithms that leverage biological networks to connect different types of experimental data and detect surprising relationships among them. We use such techniques to study human disease, in particular cancer and viral infection. We also focus on the dynamic behaviors of biological networks and develop techniques to reconstruct dynamic models of signaling pathways and transcriptional regulatory networks from high-throughput proteomic and transcriptomic data. In addition, we use machine learning to prioritize biological experiments for drug discovery, protein engineering, and other biomedical challenges.