GOname GO GO.term set.means set.sd n.genes z.score lead.genes GO:0006824 BP cobalt ion transport 0.25 0.5 4 4.87427048978238 TCN1 GO:0008236 MF serine-type peptidase activity 0.0628930817610063 0.236951487616095 159 6.67914431907457 TMPRSS11B KLK7 KLK13 PRSS3 DKFZP586H2123 TMPRSS11E KLK12 KLK5 PRSS27 DPP4 KLK10 GO:0006690 BP icosanoid metabolic process 0.121951219512195 0.31185909889079 41 7.24386594111664 HPGD CYP2J2 PLA2G4A RNPEPL1 ALOX15B ALOX12 GO:0006691 BP leukotriene metabolic process 0.136363636363636 0.315542547950509 22 5.99358133092608 HPGD RNPEPL1 ALOX15B ALOX12 GO:0002221 BP pattern recognition receptor signaling pathway 0.25 0.5 4 4.87427048978238 NOD2 GO:0002224 BP toll-like receptor signaling pathway 0.25 0.5 4 4.87427048978238 NOD2 GO:0009395 BP phospholipid catabolic process 0.153846153846154 0.375533808099405 13 5.24964880187442 PLA2G4A PLA2G4F GO:0002218 BP activation of innate immune response 0.2 0.447213595499958 5 4.30842705698279 NOD2 GO:0008544 BP epidermis development 0.0708333333333333 0.245084733532393 120 6.6864927029907 SCEL SPINK5 KLK7 KRT32 LOR IVL KLK5 EMP1 CST6 DLL1 GO:0002758 BP innate immune response-activating signal transduction 0.2 0.447213595499958 5 4.30842705698279 NOD2 GO:0046456 BP icosanoid biosynthetic process 0.103448275862069 0.279646152205514 29 5.0720038507399 HPGD RNPEPL1 ALOX15B ALOX12 GO:0004179 MF membrane alanyl aminopeptidase activity 0.136363636363636 0.323334895341432 11 4.2366430806796 RNPEPL1 TRHDE GO:0016116 BP carotenoid metabolic process 0.2 0.447213595499958 5 4.30842705698279 BCDO2 GO:0016101 BP diterpenoid metabolic process 0.181818181818182 0.404519917477945 11 5.7759191923545 BCDO2 RDH12 GO:0016108 BP tetraterpenoid metabolic process 0.2 0.447213595499958 5 4.30842705698279 BCDO2 GO:0004252 MF serine-type endopeptidase activity 0.0694444444444444 0.248147761580296 144 7.15934422608933 TMPRSS11B KLK7 KLK13 PRSS3 DKFZP586H2123 TMPRSS11E KLK12 KLK5 PRSS27 DPP4 KLK10 GO:0016284 MF alanine aminopeptidase activity 0.136363636363636 0.323334895341432 11 4.2366430806796 RNPEPL1 TRHDE GO:0018149 BP peptide cross-linking 0.111111111111111 0.323380833381777 18 4.32656386370544 LOR IVL GO:0016841 MF ammonia-lyase activity 0.25 0.5 4 4.87427048978238 CRYM GO:0031579 BP membrane raft organization and biogenesis 0.25 0.5 4 4.87427048978238 MAL GO:0016559 BP peroxisome fission 0.25 0.5 4 4.87427048978238 PEX11G GO:0042386 BP hemocyte differentiation 0.1875 0.372011904571422 8 5.08933012309526 MAL BLNK GO:0005497 MF androgen binding 0.375 0.478713553878169 4 7.42631224874087 SCGB2A1 AR GO:0031638 BP zymogen activation 0.25 0.5 4 4.87427048978238 PRSS3 GO:0004620 MF phospholipase activity 0.05625 0.224929665518757 80 4.117929558914 PLA2G4A MGLL PLCD4 PLA2G4F SMPD2 GO:0004622 MF lysophospholipase activity 0.181818181818182 0.404519917477945 11 5.7759191923545 PLA2G4A MGLL GO:0048729 BP tissue morphogenesis 0.0648148148148148 0.238831595684354 54 4.02395501874248 SPINK5 LOR IVL DLL1 GO:0048730 BP epidermis morphogenesis 0.0897435897435897 0.277957656558344 39 5.00904744874882 SPINK5 LOR IVL DLL1 GO:0000271 BP polysaccharide biosynthetic process 0.0862068965517241 0.269555371903747 29 4.12345739110921 GYS2 B3GNT8 PPP1R3C GO:0007398 BP ectoderm development 0.0648854961832061 0.235314409680763 131 6.29095158124732 SCEL SPINK5 KLK7 KRT32 LOR IVL KLK5 EMP1 CST6 DLL1 GO:0005149 MF interleukin-1 receptor binding 0.153846153846154 0.375533808099405 13 5.24964880187442 IL18 IL1F5 GO:0019369 BP arachidonic acid metabolic process 0.25 0.5 4 4.87427048978238 HPGD GO:0019370 BP leukotriene biosynthetic process 0.166666666666667 0.342997170285018 18 6.73370612049041 HPGD RNPEPL1 ALOX15B ALOX12 GO:0033692 BP cellular polysaccharide biosynthetic process 0.0862068965517241 0.269555371903747 29 4.12345739110921 GYS2 B3GNT8 PPP1R3C GO:0042253 BP granulocyte macrophage colony-stimulating factor biosynthetic process 0.2 0.447213595499958 5 4.30842705698279 IL18 GO:0004957 MF prostaglandin E receptor activity 0.2 0.447213595499958 5 4.30842705698279 HPGD GO:0004904 MF interferon receptor activity 0.2 0.447213595499958 5 4.30842705698279 IL22RA1 GO:0009913 BP epidermal cell differentiation 0.106060606060606 0.299936862042866 33 5.56450982214745 SPINK5 LOR IVL DLL1 GO:0042573 BP retinoic acid metabolic process 0.25 0.5 4 4.87427048978238 BCDO2 GO:0005576 CC extracellular region 0.0246478873239437 0.149308031515524 1704 5.96934332746934 RPTN A2ML1 GPX3 APOD SPOCK1 PROM1 ACPP TFF3 SPINK5 TCN1 KLK7 KLK13 MMP3 SCGB2A1 IL18 SPINK2 SCGB1D2 DEFB4 PRSS3 CRISP3 CRISP2 SOSTDC1 DKFZP586H2123 SLURP1 TMPRSS11E CHIA KLK12 IL1F5 KLK5 SPINK7 FAM3D LOC124220 PRSS27 SBSN IGFL1 SFTPG EREG QSOX1 DKK3 DPP4 CST6 PRRG4 BTC EDN3 KLK10 MUC5B COL9A2 DLL1 GO:0005501 MF retinoid binding 0.142857142857143 0.363136519601281 14 5.02812680547263 APOD RBP7 GO:0005626 CC insoluble fraction 0.15 0.366347548532523 20 6.33714101320746 MAL LOR GYS2 GO:0005615 CC extracellular space 0.031 0.169104087427742 500 4.57830136842474 A2ML1 GPX3 APOD SPOCK1 PROM1 MMP3 IL18 SCGB1D2 PRSS3 CRISP2 SLURP1 CHIA IL1F5 KLK5 EREG QSOX1 DKK3 GO:0042640 BP anagen 0.2 0.447213595499958 5 4.30842705698279 SPINK5 GO:0015355 MF secondary active monocarboxylate transmembrane transporter activity 0.2 0.447213595499958 5 4.30842705698279 SLC16A7 GO:0015379 MF potassium:chloride symporter activity 0.25 0.5 4 4.87427048978238 SLC12A6 GO:0019840 MF isoprenoid binding 0.142857142857143 0.363136519601281 14 5.02812680547263 APOD RBP7 GO:0007586 BP digestion 0.0632183908045977 0.238754005216002 87 4.9604839721192 TFF3 MMP3 SLC5A1 PRSS3 CHIA SLC15A1 GO:0007516 BP hemocyte development 0.214285714285714 0.393397896234722 7 5.48398721689818 MAL BLNK GO:0015293 MF symporter activity 0.0451388888888889 0.19534078563634 144 4.16883928304969 SLC16A9 SLC5A1 SLC16A7 SLC12A6 SLC37A2 SLC22A5 SLC16A6 SLC15A1 GO:0045176 BP apical protein localization 0.25 0.462910049886276 8 6.89412195327768 MAL SHROOM3 GO:0001523 BP retinoid metabolic process 0.181818181818182 0.404519917477945 11 5.7759191923545 BCDO2 RDH12 GO:0001533 CC cornified envelope 0.21875 0.406970514902493 16 8.47570166989352 SCEL LOR IVL CST6 GO:0017171 MF serine hydrolase activity 0.0625 0.236257507950315 160 6.64932075974638 TMPRSS11B KLK7 KLK13 PRSS3 DKFZP586H2123 TMPRSS11E KLK12 KLK5 PRSS27 DPP4 KLK10 GO:0017114 MF wide-spectrum protease inhibitor activity 0.2 0.447213595499958 5 4.30842705698279 A2ML1 GO:0019961 MF interferon binding 0.2 0.447213595499958 5 4.30842705698279 IL22RA1 GO:0015889 BP cobalamin transport 0.25 0.5 4 4.87427048978238 TCN1 GO:0030057 CC desmosome 0.166666666666667 0.353553390593274 9 4.76010840566595 DSG1 PKP3 GO:0015643 MF toxin binding 0.25 0.5 4 4.87427048978238 DSG1 GO:0008035 MF high-density lipoprotein binding 0.25 0.5 4 4.87427048978238 APOD GO:0043450 BP alkene biosynthetic process 0.166666666666667 0.342997170285018 18 6.73370612049041 HPGD RNPEPL1 ALOX15B ALOX12 GO:0032604 BP granulocyte macrophage colony-stimulating factor production 0.2 0.447213595499958 5 4.30842705698279 IL18 GO:0043449 BP alkene metabolic process 0.136363636363636 0.315542547950509 22 5.99358133092608 HPGD RNPEPL1 ALOX15B ALOX12 GO:0030431 BP sleep 0.2 0.447213595499958 5 4.30842705698279 IL18 GO:0030141 CC secretory granule 0.090909090909091 0.291937104060571 33 4.67519596538621 TFF3 SPINK5 CRISP3 GO:0051289 BP protein homotetramerization 0.166666666666667 0.353553390593274 9 4.76010840566595 GPX3 ALDH5A1 GO:0006775 BP fat-soluble vitamin metabolic process 0.117647058823529 0.332105582077536 17 4.47973839445834 BCDO2 RDH12 GO:0006776 BP vitamin A metabolic process 0.142857142857143 0.363136519601281 14 5.02812680547263 BCDO2 RDH12 GO:0006720 BP isoprenoid metabolic process 0.0925925925925926 0.278631167738513 27 4.31744169600888 BCDO2 RDH12 MVK GO:0006721 BP terpenoid metabolic process 0.142857142857143 0.363136519601281 14 5.02812680547263 BCDO2 RDH12 GO:0008195 MF phosphatidate phosphatase activity 0.2 0.447213595499958 5 4.30842705698279 LPPR4 GO:0030216 BP keratinocyte differentiation 0.134615384615385 0.333397429734913 26 6.42546399390096 SCEL LOR IVL EREG GO:0008105 BP asymmetric protein localization 0.2 0.421637021355784 10 6.09398907069631 MAL SHROOM3