GOname	GO	GO.term	set.means	set.sd	n.genes	z.score	lead.genes
GO:0002028	BP	regulation of sodium ion transport	0.5	0.577350269189626	4	12.3361438626731	SCNN1B ADRB2
GO:0001533	CC	cornified envelope	0.40625	0.490535421758715	16	19.988063120643	SCEL SPRR1B TGM1 SPRR2D SPRR1A IVL CNFN
GO:0047115	MF	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	0.375	0.478713553878169	4	9.20827869372857	AKR1C1 AKR1C3
GO:0031424	BP	keratinization	0.363636363636364	0.492365963917331	22	20.9403667275375	SPRR1B TGM1 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0030216	BP	keratinocyte differentiation	0.307692307692308	0.448930352658919	26	19.1959585766676	SCEL FOXN1 SPRR1B S100A7 TGM1 SPRR2D SPRR1A IVL SPRR3
GO:0018149	BP	peptide cross-linking	0.277777777777778	0.460888598962477	18	14.3793510057040	SPRR1B TGM1 TGM5 SPRR1A IVL
GO:0009913	BP	epidermal cell differentiation	0.272727272727273	0.452267016866645	33	19.1156401717460	SPRR1B SPINK5 TGM1 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0031649	BP	heat generation	0.25	0.5	4	6.08041352478405	ADRB2
GO:0040015	BP	negative regulation of multicellular organism growth	0.25	0.5	4	6.08041352478405	ADRB2
GO:0002029	BP	desensitization of G-protein coupled receptor protein signaling pathway	0.25	0.5	4	6.08041352478405	ADRB2
GO:0022401	BP	adaptation of signaling pathway	0.25	0.5	4	6.08041352478405	ADRB2
GO:0045909	BP	positive regulation of vasodilation	0.25	0.5	4	6.08041352478405	ADRB2
GO:0031579	BP	membrane raft organization and biogenesis	0.25	0.5	4	6.08041352478405	MAL
GO:0006824	BP	cobalt ion transport	0.25	0.5	4	6.08041352478405	TCN1
GO:0015889	BP	cobalamin transport	0.25	0.5	4	6.08041352478405	TCN1
GO:0019369	BP	arachidonic acid metabolic process	0.25	0.5	4	6.08041352478405	HPGD
GO:0005497	MF	androgen binding	0.25	0.5	4	6.08041352478405	SCGB2A1
GO:0050327	MF	testosterone 17-beta-dehydrogenase activity	0.25	0.5	4	6.08041352478405	AKR1C3
GO:0048730	BP	epidermis morphogenesis	0.230769230769231	0.426832794918354	39	17.5028563574662	SPRR1B SPINK5 TGM1 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0003810	MF	protein-glutamine gamma-glutamyltransferase activity	0.222222222222222	0.440958551844098	9	8.07927388327928	TGM1 TGM5
GO:0004033	MF	aldo-keto reductase activity	0.208333333333333	0.39648073054938	12	8.7279157953583	AKR1C1 AKR1B10 AKR1C3
GO:0022898	BP	regulation of transmembrane transporter activity	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0032409	BP	regulation of transporter activity	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0032412	BP	regulation of ion transmembrane transporter activity	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0001993	BP	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0003085	BP	negative regulation of systemic arterial blood pressure	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0045823	BP	positive regulation of heart contraction	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0050873	BP	brown fat cell differentiation	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0043271	BP	negative regulation of ion transport	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0045744	BP	negative regulation of G-protein coupled receptor protein signaling pathway	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0045778	BP	positive regulation of ossification	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0045932	BP	negative regulation of muscle contraction	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0048638	BP	regulation of developmental growth	0.2	0.447213595499958	5	5.39945560873276	ADRB2
GO:0042640	BP	anagen	0.2	0.447213595499958	5	5.39945560873276	SPINK5
GO:0008243	MF	plasminogen activator activity	0.2	0.447213595499958	5	5.39945560873276	SERPINB2
GO:0003840	MF	gamma-glutamyltransferase activity	0.2	0.447213595499958	5	5.39945560873276	GGT6
GO:0004957	MF	prostaglandin E receptor activity	0.2	0.447213595499958	5	5.39945560873276	HPGD
GO:0030506	MF	ankyrin binding	0.2	0.447213595499958	5	5.39945560873276	RHCG
GO:0015280	MF	amiloride-sensitive sodium channel activity	0.1875	0.372011904571422	8	6.38807527700612	SCNN1G SCNN1B
GO:0016755	MF	transferase activity, transferring amino-acyl groups	0.1875	0.403112887414928	16	9.03638561866714	TGM1 TGM5 GGT6
GO:0048729	BP	tissue morphogenesis	0.175925925925926	0.378146016115261	54	15.5550605067515	EYA2 SPRR1B SPINK5 TGM1 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0042312	BP	regulation of vasodilation	0.166666666666667	0.408248290463863	6	4.89337301869484	ADRB2
GO:0010224	BP	response to UV-B	0.166666666666667	0.408248290463863	6	4.89337301869484	IVL
GO:0042572	BP	retinol metabolic process	0.166666666666667	0.408248290463863	6	4.89337301869484	RDH12
GO:0008889	MF	glycerophosphodiester phosphodiesterase activity	0.166666666666667	0.408248290463863	6	4.89337301869484	GDPD3
GO:0008544	BP	epidermis development	0.1625	0.3618492420188	120	21.3898506004378	SCEL FOXN1 POU2F3 CRABP2 KRT15 SPRR1B SPINK5 KRT1 S100A7 TGM1 GJB5 KRT31 ALOX12B TGM5 KRT13 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0050381	MF	unspecific monooxygenase activity	0.16	0.374165738677394	25	9.57722755548872	CYP4B1 CYP4F12 CYP2C18 CYP4X1
GO:0007398	BP	ectoderm development	0.148854961832061	0.349145420929389	131	20.3946946332227	SCEL FOXN1 POU2F3 CRABP2 KRT15 SPRR1B SPINK5 KRT1 S100A7 TGM1 GJB5 KRT31 ALOX12B TGM5 KRT13 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0045776	BP	negative regulation of blood pressure	0.142857142857143	0.377964473009227	7	4.49739123321367	ADRB2
GO:0001659	BP	thermoregulation	0.142857142857143	0.377964473009227	7	4.49739123321367	ADRB2
GO:0008333	BP	endosome to lysosome transport	0.142857142857143	0.377964473009227	7	4.49739123321367	ADRB2
GO:0030279	BP	negative regulation of ossification	0.142857142857143	0.377964473009227	7	4.49739123321367	ADRB2
GO:0034105	BP	positive regulation of tissue remodeling	0.142857142857143	0.377964473009227	7	4.49739123321367	ADRB2
GO:0046852	BP	positive regulation of bone remodeling	0.142857142857143	0.377964473009227	7	4.49739123321367	ADRB2
GO:0048820	BP	hair follicle maturation	0.142857142857143	0.377964473009227	7	4.49739123321367	SPINK5
GO:0018205	BP	peptidyl-lysine modification	0.142857142857143	0.377964473009227	7	4.49739123321367	IVL
GO:0006750	BP	glutathione biosynthetic process	0.142857142857143	0.377964473009227	7	4.49739123321367	GGT6
GO:0007516	BP	hemocyte development	0.142857142857143	0.377964473009227	7	4.49739123321367	MAL
GO:0016165	MF	lipoxygenase activity	0.142857142857143	0.377964473009227	7	4.49739123321367	ALOX12B
GO:0031419	MF	cobalamin binding	0.142857142857143	0.377964473009227	7	4.49739123321367	TCN1
GO:0004908	MF	interleukin-1 receptor activity	0.142857142857143	0.377964473009227	7	4.49739123321367	IL1R2
GO:0016712	MF	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	0.133333333333333	0.34574590364176	30	8.66406815129035	CYP4B1 CYP4F12 CYP2C18 CYP4X1
GO:0009409	BP	response to cold	0.125	0.353553390593274	8	4.17606127544102	ADRB2
GO:0045176	BP	apical protein localization	0.125	0.353553390593274	8	4.17606127544102	MAL
GO:0007567	BP	parturition	0.125	0.353553390593274	8	4.17606127544102	HPGD
GO:0042386	BP	hemocyte differentiation	0.125	0.353553390593274	8	4.17606127544102	MAL
GO:0015695	BP	organic cation transport	0.125	0.353553390593274	8	4.17606127544102	RHCG
GO:0004955	MF	prostaglandin receptor activity	0.125	0.353553390593274	8	4.17606127544102	HPGD
GO:0006692	BP	prostanoid metabolic process	0.117647058823529	0.332105582077536	17	5.70986869478136	HPGD AKR1C3
GO:0006693	BP	prostaglandin metabolic process	0.117647058823529	0.332105582077536	17	5.70986869478136	HPGD AKR1C3
GO:0006940	BP	regulation of smooth muscle contraction	0.117647058823529	0.332105582077536	17	5.70986869478136	NMU ADRB2
GO:0030073	BP	insulin secretion	0.117647058823529	0.332105582077536	17	5.70986869478136	FAM3B FAM3D
GO:0043269	BP	regulation of ion transport	0.111111111111111	0.323380833381777	18	5.52849984663146	SCNN1B ADRB2
GO:0019370	BP	leukotriene biosynthetic process	0.111111111111111	0.323380833381777	18	5.52849984663146	HPGD ALOX12B
GO:0043450	BP	alkene biosynthetic process	0.111111111111111	0.323380833381777	18	5.52849984663146	HPGD ALOX12B
GO:0004867	MF	serine-type endopeptidase inhibitor activity	0.108433734939759	0.302914629878480	83	11.5901350351324	A2ML1 PI3 SLPI SERPINB2 SPINK5 SERPINB3 SERPINB4 SERPINB13 SPINK7 WFDC5
GO:0030162	BP	regulation of proteolysis	0.105263157894737	0.315301767642306	19	5.36109688945656	SERPINB4 SERPINB13
GO:0005922	CC	connexon complex	0.105263157894737	0.315301767642306	19	5.36109688945656	GJB5 GJB6
GO:0005626	CC	insoluble fraction	0.1	0.307793505625546	20	5.2059050774266	MAL S100A12
GO:0006691	BP	leukotriene metabolic process	0.090909090909091	0.29424494316825	22	4.92655053482732	HPGD ALOX12B
GO:0043449	BP	alkene metabolic process	0.090909090909091	0.29424494316825	22	4.92655053482732	HPGD ALOX12B
GO:0030141	CC	secretory granule	0.090909090909091	0.291937104060571	33	6.03586616980372	TFF3 SPINK5 CRISP3
GO:0006081	BP	aldehyde metabolic process	0.088235294117647	0.264297069935462	17	4.19200820061342	ALDH3B2 AKR1B10
GO:0042383	CC	sarcolemma	0.088235294117647	0.264297069935462	17	4.19200820061342	KRT8 ADRB2
GO:0016628	MF	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	0.088235294117647	0.264297069935462	17	4.19200820061342	AKR1C1 AKR1C3
GO:0002790	BP	peptide secretion	0.0869565217391304	0.288104065520030	23	4.80012474256139	FAM3B FAM3D
GO:0030072	BP	peptide hormone secretion	0.0869565217391304	0.288104065520030	23	4.80012474256139	FAM3B FAM3D
GO:0030855	BP	epithelial cell differentiation	0.0833333333333333	0.280305955290694	36	5.7355767055183	SPINK5 KRT4 RHCG
GO:0005921	CC	gap junction	0.0833333333333333	0.28232985128664	24	4.68130218437123	GJB5 GJB6
GO:0048585	BP	negative regulation of response to stimulus	0.08	0.276887462097269	25	4.56932234032599	SPINK5 ADRB2
GO:0042562	MF	hormone binding	0.08	0.276887462097269	25	4.56932234032599	SCGB2A1 ADRB2
GO:0016324	CC	apical plasma membrane	0.0797101449275362	0.266005147089149	69	7.57152231322558	SCNN1G MAL SCNN1B ADRB2 RHCG GJB6
GO:0009888	BP	tissue development	0.076241134751773	0.257353182432851	282	14.6758302060625	SCEL FOXN1 POU2F3 PITX1 EYA2 CRABP2 KRT15 SPRR1B SPINK5 KRT1 S100A7 TGM1 GJB5 ADRB2 KRT31 ALOX12B TGM5 KRT13 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN
GO:0005882	CC	intermediate filament	0.075	0.256429917367316	120	9.35327734078478	NEFH KRT8 KRT15 SPRR1B KRT1 KRT31 KRT13 KRT4 FLG KRT24
GO:0045111	CC	intermediate filament cytoskeleton	0.075	0.256429917367316	120	9.35327734078478	NEFH KRT8 KRT15 SPRR1B KRT1 KRT31 KRT13 KRT4 FLG KRT24
GO:0006690	BP	icosanoid metabolic process	0.073170731707317	0.263651654881875	41	5.30679995627784	HPGD ALOX12B AKR1C3
GO:0030414	MF	protease inhibitor activity	0.071969696969697	0.248142532895851	132	9.37618168961552	A2ML1 PI3 MUC5B SLPI SERPINB2 SPINK5 SERPINB3 SERPINB4 SERPINB13 SPINK7 WFDC5
GO:0004866	MF	endopeptidase inhibitor activity	0.0703125	0.24889025346067	128	8.9963487615306	A2ML1 PI3 SLPI SERPINB2 SPINK5 SERPINB3 SERPINB4 SERPINB13 SPINK7 WFDC5
GO:0009266	BP	response to temperature stimulus	0.0689655172413793	0.257880714777564	29	4.17788332751779	ADRB2 CRNN
GO:0046456	BP	icosanoid biosynthetic process	0.0689655172413793	0.257880714777564	29	4.17788332751779	HPGD ALOX12B
GO:0045177	CC	apical part of cell	0.0632183908045977	0.238754005216002	87	6.57716397653707	SCNN1G MAL SCNN1B ADRB2 RHCG GJB6
GO:0004252	MF	serine-type endopeptidase activity	0.0520833333333333	0.210881848071743	144	6.79787172226911	PRSS3 KLK10 TMPRSS4 TMPRSS11B SERPINB2 KLK11 TMPRSS11D KLK12 PRSS27
GO:0005200	MF	structural constituent of cytoskeleton	0.0481927710843374	0.215475337156518	83	4.7063904761628	KRT15 KRT1 KRT31 KRT13
GO:0002009	BP	morphogenesis of an epithelium	0.0476190476190476	0.214669395370546	63	4.04065331176732	SPINK5 KRT4 RHCG
GO:0008236	MF	serine-type peptidase activity	0.0471698113207547	0.201202499152357	159	6.36757791398539	PRSS3 KLK10 TMPRSS4 TMPRSS11B SERPINB2 KLK11 TMPRSS11D KLK12 PRSS27
GO:0017171	MF	serine hydrolase activity	0.046875	0.200603452819284	160	6.3408860271938	PRSS3 KLK10 TMPRSS4 TMPRSS11B SERPINB2 KLK11 TMPRSS11D KLK12 PRSS27
GO:0007586	BP	digestion	0.0459770114942529	0.196364988650495	87	4.55981728069604	AKR1C1 PRSS3 TFF3 NMU AKR1B10
GO:0016616	MF	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.0459183673469388	0.204167087095293	98	4.83390906416031	AKR1C1 HPGD AKR1B10 AKR1C3 RDH12
GO:0004857	MF	enzyme inhibitor activity	0.0439330543933054	0.197555469594446	239	7.19605732099626	A2ML1 PI3 MUC5B PKIA SLPI SERPINB2 SPINK5 SERPINB3 SERPINB4 SERPINB13 SPINK7 WFDC5
GO:0004497	MF	monooxygenase activity	0.0434782608695652	0.205048559151556	92	4.38905946880031	CYP4B1 CYP4F12 CYP2C18 CYP4X1
GO:0016705	MF	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.0427350427350427	0.203129073674266	117	4.85259499572423	CYP4B1 BBOX1 CYP4F12 CYP2C18 CYP4X1
GO:0016614	MF	oxidoreductase activity, acting on CH-OH group of donors	0.0416666666666667	0.194851968734283	108	4.52151725806997	AKR1C1 HPGD AKR1B10 AKR1C3 RDH12
GO:0005506	MF	iron ion binding	0.0266159695817490	0.155235455403165	263	4.01178316665881	TF NDUFS7 CYP4B1 BBOX1 CYP4F12 ALOX12B CYP2C18 CYP4X1
GO:0005576	CC	extracellular region	0.0228873239436620	0.145609848733752	1704	8.68114964960185	A2ML1 TF PI3 PRSS3 KLK10 MUC5B FLRT3 MUC15 PDZK1IP1 SLPI FCGBP S100A9 PIGR PROM1 SERPINB2 TFF3 FGFBP1 SPINK5 KLK11 TCN1 S100A7 SCGB2A1 NMU LGALS7 SCGB1D2 TMPRSS11D CRISP3 ECM1 DEFB1 SERPINB4 LCN2 KLK12 SPINK7 C20orf114 FAM3B FAM3D C10orf99 LOC124220 LRG1 KRTDAP PRSS27 SBSN WFDC5
GO:0048513	BP	organ development	0.0227272727272727	0.144450948763103	1100	6.76170364967572	SCEL FOXN1 TLE2 POU2F3 PITX1 EYA2 CRABP2 KRT15 MAL SPRR1B SPINK5 KRT1 S100A7 TGM1 ISL1 GJB5 ADRB2 KRT31 ALOX12B TGM5 KRT13 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN GJB6
GO:0005198	MF	structural molecule activity	0.0223765432098765	0.144050159366034	648	4.9979422213818	NEFH KRT8 MUC5B KRT15 MAL SPRR1B KRT1 KRT31 KRT13 SPRR2D KRT4 SPRR1A IVL FLG SPRR3 KRT24
GO:0009653	BP	anatomical structure morphogenesis	0.0220858895705521	0.142815038143963	815	5.52956670124301	FOXN1 TLE2 PITX1 EYA2 SPRR1B SPINK5 KRT1 S100A7 TGM1 ISL1 ADRB2 SPRR2D KRT4 SPRR1A IVL SPRR3 RHCG LCE3D CNFN GJB6
GO:0048731	BP	system development	0.0172189733593242	0.124380642976268	1539	5.2747766148996	SCEL FOXN1 TF NEFH TLE2 MPPED2 POU2F3 PITX1 EYA2 CRABP2 KRT15 MAL SPRR1B SPINK5 KRT1 S100A7 TGM1 ISL1 GJB5 ADRB2 KRT31 ALOX12B TGM5 KRT13 SPRR2D SPRR1A IVL SPRR3 LCE3D CNFN GJB6
GO:0048856	BP	anatomical structure development	0.0160744500846024	0.120645082738774	1773	5.06874408116475	SCEL FOXN1 TF NEFH TLE2 MPPED2 POU2F3 PITX1 EYA2 CRABP2 KRT15 MAL SPRR1B SPINK5 KRT1 S100A7 TGM1 ISL1 GJB5 ADRB2 KRT31 ALOX12B TGM5 KRT13 SPRR2D KRT4 SPRR1A IVL SPRR3 RHCG LCE3D CNFN GJB6
GO:0043231	CC	intracellular membrane-bound organelle	0.00353862370124981	0.0557895712161244	6641	-4.63852242019934	BNIPL LASS3 FOXN1 TF NEFH TLE2 POU2F3 PITX1 EYA2 NDUFS7 FUT3 CYP4B1 TFF3 MAL SPINK5 S100A7 ISL1 ADRB2 LGALS7 CYP4F12 CRISP3 CYP2C18 MALL D4S234E FLG CLIC3 C19orf33 CYP4X1 ST6GALNAC1
GO:0043227	CC	membrane-bound organelle	0.00353755833207888	0.0557812048569768	6643	-4.64115054787342	BNIPL LASS3 FOXN1 TF NEFH TLE2 POU2F3 PITX1 EYA2 NDUFS7 FUT3 CYP4B1 TFF3 MAL SPINK5 S100A7 ISL1 ADRB2 LGALS7 CYP4F12 CRISP3 CYP2C18 MALL D4S234E FLG CLIC3 C19orf33 CYP4X1 ST6GALNAC1
GO:0043283	BP	biopolymer metabolic process	0.00282179292381159	0.0487875504022174	4607	-4.21904473166395	LASS3 FOXN1 TLE2 POU2F3 PRSS3 PITX1 EYA2 FUT3 CRABP2 SPRR1B TGM1 ISL1 ADRB2 TGM5 SPRR1A IVL ST6GALNAC1
GO:0005634	CC	nucleus	0.00256709451575263	0.045762963448685	4285	-4.2560449261616	BNIPL LASS3 FOXN1 NEFH TLE2 POU2F3 PITX1 EYA2 S100A7 ISL1 ADRB2 LGALS7 D4S234E CLIC3 C19orf33
GO:0006139	BP	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.00177514792899408	0.0364500051351056	3380	-4.2895530499957	LASS3 FOXN1 TLE2 POU2F3 PITX1 EYA2 CRABP2 ISL1 ADRB2
GO:0003676	MF	nucleic acid binding	0.00115626032375289	0.0272436867834152	3027	-4.4766884123404	LASS3 FOXN1 NEFH POU2F3 PITX1 ISL1