GOname GO GO.term set.means set.sd n.genes z.score lead.genes GO:0043616 BP keratinocyte proliferation 0.375 0.478713553878169 4 15.9327929774975 EREG KRT2 GO:0045909 BP positive regulation of vasodilation 0.25 0.5 4 10.5872213220372 EPHX2 GO:0016803 MF ether hydrolase activity 0.25 0.418330013267038 6 12.9674637469992 ALOX12 EPHX2 GO:0008035 MF high-density lipoprotein binding 0.25 0.5 4 10.5872213220372 APOD GO:0004301 MF epoxide hydrolase activity 0.25 0.5 4 10.5872213220372 EPHX2 GO:0045980 BP negative regulation of nucleotide metabolic process 0.2 0.447213595499958 5 9.4465591747898 CDA GO:0001882 MF nucleoside binding 0.2 0.447213595499958 5 9.4465591747898 CDA GO:0001517 MF N-acetylglucosamine 6-O-sulfotransferase activity 0.2 0.447213595499958 5 9.4465591747898 CHST2 GO:0008133 MF collagenase activity 0.2 0.447213595499958 5 9.4465591747898 MMP1 GO:0051289 BP protein homotetramerization 0.166666666666667 0.353553390593274 9 10.5369235884207 GPX3 CDA GO:0042312 BP regulation of vasodilation 0.166666666666667 0.408248290463863 6 8.6025471781992 EPHX2 GO:0017144 BP drug metabolic process 0.166666666666667 0.408248290463863 6 8.6025471781992 EPHX2 GO:0009898 CC internal side of plasma membrane 0.166666666666667 0.408248290463863 6 8.6025471781992 LOR GO:0005678 CC chromatin assembly complex 0.166666666666667 0.408248290463863 6 8.6025471781992 NAP1L2 GO:0016801 MF hydrolase activity, acting on ether bonds 0.166666666666667 0.353553390593274 9 10.5369235884207 ALOX12 EPHX2 GO:0004126 MF cytidine deaminase activity 0.166666666666667 0.408248290463863 6 8.6025471781992 CDA GO:0005152 MF interleukin-1 receptor antagonist activity 0.166666666666667 0.408248290463863 6 8.6025471781992 IL1F5 GO:0030353 MF fibroblast growth factor receptor antagonist activity 0.166666666666667 0.408248290463863 6 8.6025471781992 IL1F5 GO:0016165 MF lipoxygenase activity 0.142857142857143 0.243975018237133 7 7.94502127815974 ALOX15B ALOX12 GO:0005104 MF fibroblast growth factor receptor binding 0.142857142857143 0.377964473009227 7 7.94502127815974 IL1F5 GO:0004499 MF flavin-containing monooxygenase activity 0.142857142857143 0.377964473009227 7 7.94502127815974 FMO2 GO:0031424 BP keratinization 0.136363636363636 0.351250086657104 22 13.4400768684470 LOR KRT2 LCE3D GO:0043094 BP metabolic compound salvage 0.125 0.353553390593274 8 7.41374824521574 CDA GO:0006206 BP pyrimidine base metabolic process 0.125 0.353553390593274 8 7.41374824521574 CDA GO:0006213 BP pyrimidine nucleoside metabolic process 0.125 0.353553390593274 8 7.41374824521574 CDA GO:0045741 BP positive regulation of epidermal growth factor receptor activity 0.125 0.25 4 5.24164966657683 EREG GO:0030547 MF receptor inhibitor activity 0.125 0.353553390593274 8 7.41374824521574 IL1F5 GO:0048019 MF receptor antagonist activity 0.125 0.353553390593274 8 7.41374824521574 IL1F5 GO:0035251 MF UDP-glucosyltransferase activity 0.125 0.353553390593274 8 7.41374824521574 GYS2 GO:0030866 BP cortical actin cytoskeleton organization and biogenesis 0.111111111111111 0.333333333333333 9 6.97264652779746 EPB41L3 GO:0046527 MF glucosyltransferase activity 0.111111111111111 0.333333333333333 9 6.97264652779746 GYS2 GO:0006140 BP regulation of nucleotide metabolic process 0.1 0.316227766016838 10 6.59860757240204 CDA GO:0009119 BP ribonucleoside metabolic process 0.1 0.316227766016838 10 6.59860757240204 CDA GO:0045777 BP positive regulation of blood pressure 0.1 0.316227766016838 10 6.59860757240204 EPHX2 GO:0030728 BP ovulation 0.1 0.223606797749979 5 4.66518359553691 EREG GO:0005978 BP glycogen biosynthetic process 0.1 0.280305955290694 15 8.08288715561071 PPP1R3C GYS2 GO:0009250 BP glucan biosynthetic process 0.1 0.280305955290694 15 8.08288715561071 PPP1R3C GYS2 GO:0042554 BP superoxide release 0.1 0.223606797749979 5 4.66518359553691 ALOX12 GO:0030865 BP cortical cytoskeleton organization and biogenesis 0.1 0.316227766016838 10 6.59860757240204 EPB41L3 GO:0050796 BP regulation of insulin secretion 0.1 0.316227766016838 10 6.59860757240204 FAM3D GO:0009299 BP mRNA transcription 0.1 0.223606797749979 5 4.66518359553691 EREG GO:0045410 BP positive regulation of interleukin-6 biosynthetic process 0.1 0.223606797749979 5 4.66518359553691 EREG GO:0005626 CC insoluble fraction 0.1 0.307793505625546 20 9.33478867734616 LOR GYS2 GO:0030545 MF receptor regulator activity 0.1 0.316227766016838 10 6.59860757240204 IL1F5 GO:0030280 MF structural constituent of epidermis 0.1 0.316227766016838 10 6.59860757240204 LOR GO:0009913 BP epidermal cell differentiation 0.090909090909091 0.291937104060571 33 10.8780047752159 LOR KRT2 LCE3D GO:0002791 BP regulation of peptide secretion 0.090909090909091 0.301511344577764 11 6.2760538623418 FAM3D GO:0046888 BP negative regulation of hormone secretion 0.090909090909091 0.301511344577764 11 6.2760538623418 FAM3D GO:0051262 BP protein tetramerization 0.0833333333333333 0.257247877713763 18 7.34257385117597 GPX3 CDA GO:0042311 BP vasodilation 0.0833333333333333 0.257247877713763 18 7.34257385117597 CTTNBP2 EPHX2 GO:0048599 BP oocyte development 0.0833333333333333 0.204124145231932 6 4.23763060939924 EREG GO:0009746 BP response to hexose stimulus 0.0833333333333333 0.288675134594813 12 5.99405023953985 GYS2 GO:0009749 BP response to glucose stimulus 0.0833333333333333 0.288675134594813 12 5.99405023953985 GYS2 GO:0034284 BP response to monosaccharide stimulus 0.0833333333333333 0.288675134594813 12 5.99405023953985 GYS2 GO:0051148 BP negative regulation of muscle cell differentiation 0.0833333333333333 0.204124145231932 6 4.23763060939924 EREG GO:0015198 MF oligopeptide transporter activity 0.0833333333333333 0.204124145231932 6 4.23763060939924 SLC15A1 GO:0048730 BP epidermis morphogenesis 0.0769230769230769 0.269952762399508 39 9.9582305488669 LOR KRT2 LCE3D GO:0005149 MF interleukin-1 receptor binding 0.0769230769230769 0.277350098112615 13 5.74466360431318 IL1F5 GO:0006800 BP oxygen and reactive oxygen species metabolic process 0.073170731707317 0.238772266232809 41 9.69667608467181 GPX3 ALOX12 EPHX2 FMO2 GO:0019233 BP sensory perception of pain 0.0714285714285714 0.267261241912424 14 5.52197967321488 EPHX2 GO:0005501 MF retinoid binding 0.0714285714285714 0.267261241912424 14 5.52197967321488 APOD GO:0019840 MF isoprenoid binding 0.0714285714285714 0.267261241912424 14 5.52197967321488 APOD GO:0030864 CC cortical actin cytoskeleton 0.0666666666666667 0.258198889747161 15 5.32148677595098 GYS2 GO:0019439 BP aromatic compound catabolic process 0.0625 0.25 16 5.13967501611231 EPHX2 GO:0009112 BP nucleobase metabolic process 0.0625 0.25 16 5.13967501611231 CDA GO:0001533 CC cornified envelope 0.0625 0.25 16 5.13967501611231 LOR GO:0005247 MF voltage-gated chloride channel activity 0.0625 0.25 16 5.13967501611231 CLIC3 GO:0009743 BP response to carbohydrate stimulus 0.0588235294117647 0.242535625036333 17 4.97376713281633 GYS2 GO:0030073 BP insulin secretion 0.0588235294117647 0.242535625036333 17 4.97376713281633 FAM3D GO:0048029 MF monosaccharide binding 0.0588235294117647 0.242535625036333 17 4.97376713281633 UPK1A GO:0030216 BP keratinocyte differentiation 0.0576923076923077 0.215727748652002 26 6.02935576643278 EREG LOR GO:0048729 BP tissue morphogenesis 0.0555555555555556 0.231212282322664 54 8.36065493294325 LOR KRT2 LCE3D GO:0019370 BP leukotriene biosynthetic process 0.0555555555555556 0.161690416690889 18 4.8215327935035 ALOX15B ALOX12 GO:0043450 BP alkene biosynthetic process 0.0555555555555556 0.161690416690889 18 4.8215327935035 ALOX15B ALOX12 GO:0018149 BP peptide cross-linking 0.0555555555555556 0.235702260395516 18 4.8215327935035 LOR GO:0009636 BP response to toxin 0.0526315789473684 0.229415733870562 19 4.68115737547458 EPHX2 GO:0000271 BP polysaccharide biosynthetic process 0.0517241379310345 0.204626296409494 29 5.68055271205773 PPP1R3C GYS2 GO:0033692 BP cellular polysaccharide biosynthetic process 0.0517241379310345 0.204626296409494 29 5.68055271205773 PPP1R3C GYS2 GO:0030574 BP collagen catabolic process 0.05 0.223606797749979 20 4.55114729375206 MMP1 GO:0044254 BP multicellular organismal protein catabolic process 0.05 0.223606797749979 20 4.55114729375206 MMP1 GO:0044256 BP protein digestion 0.05 0.223606797749979 20 4.55114729375206 MMP1 GO:0044259 BP multicellular organismal macromolecule metabolic process 0.05 0.223606797749979 20 4.55114729375206 MMP1 GO:0044266 BP multicellular organismal macromolecule catabolic process 0.05 0.223606797749979 20 4.55114729375206 MMP1 GO:0044268 BP multicellular organismal protein metabolic process 0.05 0.223606797749979 20 4.55114729375206 MMP1 GO:0008308 MF voltage-gated anion channel activity 0.0476190476190476 0.218217890235992 21 4.43026042254769 CLIC3 GO:0006691 BP leukotriene metabolic process 0.0454545454545455 0.147122471584125 22 4.31745410906199 ALOX15B ALOX12 GO:0043449 BP alkene metabolic process 0.0454545454545455 0.147122471584125 22 4.31745410906199 ALOX15B ALOX12 GO:0044243 BP multicellular organismal catabolic process 0.0454545454545455 0.213200716355610 22 4.31745410906199 MMP1 GO:0015833 BP peptide transport 0.0454545454545455 0.192176528696452 33 5.2896189762683 SLC15A1 FAM3D GO:0032963 BP collagen metabolic process 0.0454545454545455 0.213200716355610 22 4.31745410906199 MMP1 GO:0051260 BP protein homooligomerization 0.0441176470588235 0.189402851840211 34 5.20249504651768 GPX3 CDA GO:0002790 BP peptide secretion 0.0434782608695652 0.208514414057075 23 4.21184575240836 FAM3D GO:0030072 BP peptide hormone secretion 0.0434782608695652 0.208514414057075 23 4.21184575240836 FAM3D GO:0006044 BP N-acetylglucosamine metabolic process 0.0434782608695652 0.208514414057075 23 4.21184575240836 CHST2 GO:0050661 MF NADP binding 0.0434782608695652 0.208514414057075 23 4.21184575240836 FMO2 GO:0051259 BP protein oligomerization 0.0416666666666667 0.190709350838324 60 6.51013392967236 GPX3 CDA UPK1A GO:0005977 BP glycogen metabolic process 0.0416666666666667 0.184197099403252 36 5.0388983800282 PPP1R3C GYS2 GO:0044236 BP multicellular organismal metabolic process 0.0416666666666667 0.204124145231932 24 4.11268250855327 MMP1 GO:0030855 BP epithelial cell differentiation 0.0416666666666667 0.184197099403252 36 5.0388983800282 ALOX15B UPK1A GO:0051048 BP negative regulation of secretion 0.0416666666666667 0.204124145231932 24 4.11268250855327 FAM3D GO:0006041 BP glucosamine metabolic process 0.0416666666666667 0.204124145231932 24 4.11268250855327 CHST2 GO:0030863 CC cortical cytoskeleton 0.0416666666666667 0.204124145231932 24 4.11268250855327 GYS2 GO:0006073 BP glucan metabolic process 0.0405405405405405 0.181749918935424 37 4.96194472425168 PPP1R3C GYS2 GO:0005802 CC trans-Golgi network 0.04 0.2 25 4.01931772459173 CHST2 GO:0016709 MF oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 0.04 0.2 25 4.01931772459173 FMO2 GO:0035150 BP regulation of tube size 0.0375 0.174954206462647 40 4.74802325532865 CTTNBP2 EPHX2 GO:0050880 BP regulation of blood vessel size 0.0375 0.174954206462647 40 4.74802325532865 CTTNBP2 EPHX2 GO:0003018 BP vascular process in circulatory system 0.0365853658536585 0.172852679413678 41 4.68178704507087 CTTNBP2 EPHX2 GO:0006112 BP energy reserve metabolic process 0.0357142857142857 0.170825011836644 42 4.61783469755314 PPP1R3C GYS2 GO:0008544 BP epidermis development 0.0333333333333333 0.180258140451075 120 7.2651557473479 COL17A1 LOR KRT2 LCE3D GO:0007398 BP ectoderm development 0.0305343511450382 0.172712802862036 131 6.90573691246801 COL17A1 LOR KRT2 LCE3D GO:0043284 BP biopolymer biosynthetic process 0.0294117647058824 0.155298573911107 51 4.12622934353829 PPP1R3C GYS2 GO:0006821 BP chloride transport 0.0294117647058824 0.155298573911107 51 4.12622934353829 CTTNBP2 CLIC3 GO:0005200 MF structural constituent of cytoskeleton 0.0240963855421687 0.154280676631581 83 4.23119969094615 LOR KRT2 GO:0042803 MF protein homodimerization activity 0.0235294117647059 0.152025425173095 170 5.91336662720333 CDA EPHX2 GYS2 UPK1A GO:0007586 BP digestion 0.0229885057471264 0.130027858754931 87 4.11096897009709 SLC5A1 SLC15A1 MMP1 GO:0009888 BP tissue development 0.0141843971631206 0.118460804986133 282 4.25814717854003 COL17A1 LOR KRT2 LCE3D GO:0046983 MF protein dimerization activity 0.0141065830721003 0.114739524208733 319 4.50426339954961 EREG CDA EPHX2 GYS2 UPK1A GO:0005578 CC proteinaceous extracellular matrix 0.0133333333333333 0.114889312249309 300 4.07630548341519 RPTN MMP1 COL17A1 CRISP3 GO:0031012 CC extracellular matrix 0.0131147540983607 0.113953201722972 305 4.02838569381012 RPTN MMP1 COL17A1 CRISP3 GO:0005615 CC extracellular space 0.012 0.104296478900402 500 4.64895666939767 EREG GPX3 APOD MMP1 CRISP2 SLURP1 IL1F5 GO:0044421 CC extracellular region part 0.0118733509234828 0.105296585856255 758 5.69641625765195 EREG GPX3 RPTN APOD MMP1 COL17A1 CRISP3 CRISP2 SLURP1 IL1F5 GO:0005576 CC extracellular region 0.00704225352112676 0.0818728693751596 1704 4.30871402821253 EREG GPX3 RPTN APOD MMP1 COL17A1 CDA CRISP3 CRISP2 SOSTDC1 SLURP1 IL1F5 FAM3D