GOname	GO	GO.term	set.means	set.sd	n.genes	z.score	lead.genes
GO:0050000	BP	chromosome localization	0.75	0.418330013267038	6	20.1004261444681	BIRC5 DLG7 CENPE CENPF CDCA5
GO:0051303	BP	establishment of chromosome localization	0.75	0.418330013267038	6	20.1004261444681	BIRC5 DLG7 CENPE CENPF CDCA5
GO:0051310	BP	metaphase plate congression	0.75	0.5	4	16.4108930173792	CENPE CENPF CDCA5
GO:0051383	BP	kinetochore organization and biogenesis	0.75	0.5	4	16.4108930173792	CENPE CENPF CENPH
GO:0000076	BP	DNA replication checkpoint	0.666666666666667	0.516397779494322	6	17.8398398534159	CDC6 CDC45L CDT1 TIPIN
GO:0032297	BP	negative regulation of DNA replication initiation	0.666666666666667	0.516397779494322	6	17.8398398534159	CDC6 CDC45L CDT1 TIPIN
GO:0007051	BP	spindle organization and biogenesis	0.526315789473684	0.485159888035959	19	24.9813371659284	STMN1 KIF23 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK PRC1
GO:0030174	BP	regulation of DNA replication initiation	0.5	0.534522483824849	8	15.3800434456082	CDC6 CDC45L CDT1 TIPIN
GO:0016538	MF	cyclin-dependent protein kinase regulator activity	0.416666666666667	0.491596040125088	6	11.0580809802595	CCNE2 CKS2 CABLES2
GO:0000085	BP	G2 phase of mitotic cell cycle	0.4	0.547722557505166	5	9.68157029955735	BLM CENPF
GO:0051319	BP	G2 phase	0.4	0.547722557505166	5	9.68157029955735	BLM CENPF
GO:0007089	BP	traversing start control point of mitotic cell cycle	0.4	0.547722557505166	5	9.68157029955735	CDC2 CDC6
GO:0008278	CC	cohesin complex	0.4	0.547722557505166	5	9.68157029955735	CDCA5 SGOL2
GO:0000777	CC	condensed chromosome kinetochore	0.375	0.517549169506766	8	11.4643458768486	BUB1B CENPE CENPF
GO:0007052	BP	mitotic spindle organization and biogenesis	0.363636363636364	0.452267016866645	11	13.0269564421363	STMN1 KIF23 KIF11 TTK PRC1
GO:0005876	CC	spindle microtubule	0.361111111111111	0.4791400248348	18	16.5491288697083	BIRC5 SPAG5 CDC2 KIF11 KNTC1 PRC1 KIF4A
GO:0031577	BP	spindle checkpoint	0.357142857142857	0.475594865605671	7	10.2003344342344	BIRC5 TTK CENPF
GO:0007094	BP	mitotic cell cycle spindle assembly checkpoint	0.333333333333333	0.516397779494322	6	8.7974946892073	TTK CENPF
GO:0000779	CC	condensed chromosome, pericentric region	0.333333333333333	0.5	9	10.7757071701546	BUB1B CENPE CENPF
GO:0000808	CC	origin recognition complex	0.333333333333333	0.516397779494322	6	8.7974946892073	MCM2 ORC6L
GO:0005664	CC	nuclear origin of replication recognition complex	0.333333333333333	0.516397779494322	6	8.7974946892073	MCM2 ORC6L
GO:0006270	BP	DNA replication initiation	0.314814814814815	0.41943524640393	27	17.6083321329121	POLA1 MCM6 CCNE2 MCM4 MCM8 MCM5 MCM2 CDC6 CDC45L CDT1 TIPIN
GO:0007076	BP	mitotic chromosome condensation	0.3125	0.478713553878169	16	13.4476144824873	NUSAP1 SMC2 NCAPH NCAPG CDCA5
GO:0000070	BP	mitotic sister chromatid segregation	0.310344827586207	0.470823615430758	29	17.9832205675647	NUSAP1 DLG7 ZWINT NDC80 SMC2 CENPE NCAPH NCAPG CDCA5
GO:0031572	BP	G2/M transition DNA damage checkpoint	0.3	0.447213595499958	5	7.20530026862701	CCNA2 BLM
GO:0031576	BP	G2/M transition checkpoint	0.3	0.447213595499958	5	7.20530026862701	CCNA2 BLM
GO:0000819	BP	sister chromatid segregation	0.3	0.466091599699399	30	17.6632551735931	NUSAP1 DLG7 ZWINT NDC80 SMC2 CENPE NCAPH NCAPG CDCA5
GO:0030261	BP	chromosome condensation	0.3	0.470162345981627	20	14.4174294509663	NUSAP1 TOP2A SMC2 NCAPH NCAPG CDCA5
GO:0008156	BP	negative regulation of DNA replication	0.294117647058824	0.469668218313862	17	13.0222622680056	CDC6 CDC45L BLM CDT1 TIPIN
GO:0000075	BP	cell cycle checkpoint	0.25	0.421463615211762	58	20.3575230906310	BIRC5 CCNA2 CCNE2 BUB1B CDC6 ZWINT CDC45L TTK CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 ZWILCH TIPIN
GO:0007093	BP	mitotic cell cycle checkpoint	0.25	0.430516930661509	30	14.6280597060641	CCNA2 BUB1B ZWINT TTK BLM KNTC1 CENPF ZWILCH
GO:0046633	BP	alpha-beta T cell proliferation	0.25	0.5	4	5.33702637026209	BLM
GO:0001833	BP	inner cell mass cell proliferation	0.25	0.5	4	5.33702637026209	GINS1
GO:0045070	BP	positive regulation of viral genome replication	0.25	0.5	4	5.33702637026209	TOP2A
GO:0009186	BP	deoxyribonucleoside diphosphate metabolic process	0.25	0.5	4	5.33702637026209	RRM2
GO:0045091	BP	regulation of retroviral genome replication	0.25	0.5	4	5.33702637026209	TOP2A
GO:0006269	BP	DNA replication, synthesis of RNA primer	0.25	0.5	4	5.33702637026209	PRIM1
GO:0005721	CC	centric heterochromatin	0.25	0.5	4	5.33702637026209	HELLS
GO:0005658	CC	alpha DNA polymerase:primase complex	0.25	0.418330013267038	6	6.53690839815516	POLA1 PRIM1
GO:0005828	CC	kinetochore microtubule	0.25	0.5	4	5.33702637026209	KNTC1
GO:0000796	CC	condensin complex	0.25	0.5	4	5.33702637026209	SMC2
GO:0004523	MF	ribonuclease H activity	0.25	0.418330013267038	6	6.53690839815516	FEN1 RNASEH2A
GO:0002039	MF	p53 binding	0.25	0.5	4	5.33702637026209	BLM
GO:0045502	MF	dynein binding	0.25	0.5	4	5.33702637026209	CENPF
GO:0004748	MF	ribonucleoside-diphosphate reductase activity	0.25	0.5	4	5.33702637026209	RRM2
GO:0016728	MF	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	0.25	0.5	4	5.33702637026209	RRM2
GO:0051656	BP	establishment of organelle localization	0.239130434782609	0.422911048496858	23	12.2278107121664	BIRC5 NUSAP1 DLG7 CENPE CENPF CDCA5
GO:0051053	BP	negative regulation of DNA metabolic process	0.227272727272727	0.428932027228889	22	11.3424049350863	CDC6 CDC45L BLM CDT1 TIPIN
GO:0031570	BP	DNA integrity checkpoint	0.224137931034483	0.413741786637333	29	12.8382450646045	CCNA2 CDC6 CDC45L CHEK1 BLM CDT1 TIPIN
GO:0000775	CC	chromosome, pericentric region	0.222972972972973	0.389431372362425	74	20.4259826970745	SUV39H2 BIRC5 CENPA KIF2C MLF1IP CENPQ CENPO BUB1B ZWINT NDC80 CENPE CENPF SPC25 ZWILCH CENPN HELLS CENPK NUF2 SGOL2 CENPH
GO:0005819	CC	spindle	0.219178082191781	0.408131764618628	73	19.9270177845955	BIRC5 KIF23 SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA KIF11 TTK CENPE KNTC1 KIF14 CENPF PRC1 KIF4A FBXO5
GO:0007346	BP	regulation of mitotic cell cycle	0.216666666666667	0.405122566373821	60	17.8425239120865	BIRC5 CCNA2 CDC2 BUB1B CDC6 ZWINT TTK BLM KNTC1 CDKN2A CENPF CDT1 ZWILCH FBXO5
GO:0007059	BP	chromosome segregation	0.216666666666667	0.415450201656585	60	17.8425239120865	NUSAP1 TOP2A DLG7 ZWINT NDC80 SMC2 CENPE CENPF NCAPH NCAPG NUF2 CDCA5 SGOL2
GO:0033261	BP	regulation of S phase	0.214285714285714	0.42581531362632	14	8.50754044898548	CDC7 CDT1 TIPIN
GO:0005814	CC	centriole	0.214285714285714	0.393397896234722	7	6.0144098246071	BIRC5 TOP2A
GO:0006268	BP	DNA unwinding during replication	0.208333333333333	0.334278961710761	12	7.64755742943709	MCM6 RAD51 MCM4 MCM2
GO:0000086	BP	G2/M transition of mitotic cell cycle	0.205882352941176	0.397603112782229	17	8.99189719627168	BIRC5 CHEK1 CDKN2A CCNB1
GO:0008089	BP	anterograde axon cargo transport	0.2	0.447213595499958	5	4.72903023769667	KIF4A
GO:0045732	BP	positive regulation of protein catabolic process	0.2	0.447213595499958	5	4.72903023769667	BARD1
GO:0033205	BP	cytokinesis during cell cycle	0.2	0.447213595499958	5	4.72903023769667	NUSAP1
GO:0032088	BP	inhibition of NF-kappaB transcription factor	0.2	0.447213595499958	5	4.72903023769667	CDKN2A
GO:0005657	CC	replication fork	0.2	0.385066048969479	30	11.5928642385352	POLA1 RPA3 RFC4 PRIM1 CHEK1 BLM CDT1
GO:0000800	CC	lateral element	0.2	0.447213595499958	5	4.72903023769667	BLM
GO:0016019	MF	peptidoglycan receptor activity	0.2	0.447213595499958	5	4.72903023769667	CD14
GO:0008353	MF	RNA polymerase subunit kinase activity	0.2	0.447213595499958	5	4.72903023769667	CDC2
GO:0003688	MF	DNA replication origin binding	0.2	0.447213595499958	5	4.72903023769667	MCM2
GO:0003689	MF	DNA clamp loader activity	0.2	0.447213595499958	5	4.72903023769667	RFC4
GO:0033170	MF	DNA-protein loading ATPase activity	0.2	0.447213595499958	5	4.72903023769667	RFC4
GO:0003918	MF	DNA topoisomerase (ATP-hydrolyzing) activity	0.2	0.447213595499958	5	4.72903023769667	TOP2A
GO:0000776	CC	kinetochore	0.193548387096774	0.401609664451249	31	11.3867429400376	BUB1B ZWINT CENPE CENPF ZWILCH CENPH
GO:0000724	BP	double-strand break repair via homologous recombination	0.192307692307692	0.383973823894152	13	7.3200376003864	RAD51 RAD51AP1 BLM
GO:0000725	BP	recombinational repair	0.192307692307692	0.383973823894152	13	7.3200376003864	RAD51 RAD51AP1 BLM
GO:0006312	BP	mitotic recombination	0.1875	0.372011904571422	8	5.59079952370927	RAD51 BLM
GO:0006266	BP	DNA ligation	0.1875	0.372011904571422	8	5.59079952370927	RAD51 TOP2A
GO:0000922	CC	spindle pole	0.181818181818182	0.394771016975861	22	8.98010595144553	DLG7 KIF11 KNTC1 CENPF
GO:0006275	BP	regulation of DNA replication	0.178571428571429	0.39002102778748	28	9.94245183649782	CDC6 CDC45L BLM CDT1 TIPIN
GO:0032392	BP	DNA geometric change	0.178571428571429	0.316661846888325	14	7.02726541073041	MCM6 RAD51 MCM4 MCM2
GO:0032508	BP	DNA duplex unwinding	0.178571428571429	0.316661846888325	14	7.02726541073041	MCM6 RAD51 MCM4 MCM2
GO:0005871	CC	kinesin complex	0.176470588235294	0.350944104817110	17	7.64844217236036	KIF23 KIF2C KIF11 KIF15
GO:0051320	BP	S phase	0.175	0.372579910185297	20	8.22382072866052	POLA1 CDC7 CDT1 TIPIN
GO:0051640	BP	organelle localization	0.171875	0.372640426009812	32	10.2104151947414	BIRC5 NUSAP1 DLG7 CENPE CENPF CDCA5
GO:0007096	BP	regulation of exit from mitosis	0.166666666666667	0.325669473639465	12	6.04877864851562	ANLN BIRC5 KNTC1
GO:0001832	BP	blastocyst growth	0.166666666666667	0.408248290463863	6	4.27632210710301	GINS1
GO:0048524	BP	positive regulation of viral reproduction	0.166666666666667	0.408248290463863	6	4.27632210710301	TOP2A
GO:0051340	BP	regulation of ligase activity	0.166666666666667	0.408248290463863	6	4.27632210710301	FBXO5
GO:0045090	BP	retroviral genome replication	0.166666666666667	0.408248290463863	6	4.27632210710301	TOP2A
GO:0005663	CC	DNA replication factor C complex	0.166666666666667	0.408248290463863	6	4.27632210710301	RFC4
GO:0042708	MF	elastase activity	0.166666666666667	0.408248290463863	6	4.27632210710301	MMP12
GO:0015198	MF	oligopeptide transporter activity	0.166666666666667	0.408248290463863	6	4.27632210710301	SLC15A3
GO:0050699	MF	WW domain binding	0.166666666666667	0.408248290463863	6	4.27632210710301	MPHOSPH1
GO:0051325	BP	interphase	0.159090909090909	0.359960522623579	88	15.6305497444811	BIRC5 POLA1 CDKN3 CDC2 CDC6 DBF4 CDC7 CHEK1 BLM CDKN2A CENPF CDT1 CCNB1 TIPIN CDCA5
GO:0000079	BP	regulation of cyclin-dependent protein kinase activity	0.156862745098039	0.353414715008181	51	11.7087863286465	CCNA2 CCNE2 CDKN3 CDC6 CKS2 CHEK1 BLM CDKN2A HERC5
GO:0051329	BP	interphase of mitotic cell cycle	0.156626506024096	0.357222609793108	83	14.9283481144246	BIRC5 POLA1 CDKN3 CDC2 CDC6 DBF4 CDC7 CHEK1 BLM CDKN2A CENPF CDT1 CCNB1 CDCA5
GO:0010458	BP	exit from mitosis	0.153846153846154	0.315212585978058	13	5.7839321166861	ANLN BIRC5 KNTC1
GO:0045840	BP	positive regulation of mitosis	0.153846153846154	0.375533808099405	13	5.7839321166861	NUSAP1 DLG7
GO:0051301	BP	cell division	0.151785714285714	0.346922961649509	224	23.8268169214323	ANLN BIRC5 CCNA2 NEK2 KIF23 CCNE2 SYCP2 CDCA3 NUSAP1 SPAG5 CDC2 BUB1B CDC6 ZWINT NDC80 CKS2 SMC2 KIF11 CDC7 CENPE MPHOSPH1 BLM KNTC1 CENPF SPC25 NCAPH CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN HELLS NUF2 CDCA5 CABLES2 SGOL2
GO:0030496	CC	midbody	0.15	0.337474278855276	10	4.93765082898689	BIRC5 CDC2
GO:0007067	BP	mitosis	0.148058252427184	0.343825134944160	206	22.2400319218934	ANLN BIRC5 CCNA2 NEK2 KIF23 KIF2C CDCA3 NUSAP1 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 SMC2 KIF11 CENPE MPHOSPH1 KNTC1 CENPF SPC25 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HELLS NUF2 CDCA5
GO:0000082	BP	G1/S transition of mitotic cell cycle	0.147058823529412	0.359490627953571	34	8.92139122108927	CDKN3 DBF4 CDC7 CDKN2A CDCA5
GO:0000087	BP	M phase of mitotic cell cycle	0.146634615384615	0.342466502686983	208	22.1203147851949	ANLN BIRC5 CCNA2 NEK2 KIF23 KIF2C CDCA3 NUSAP1 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 SMC2 KIF11 CENPE MPHOSPH1 KNTC1 CENPF SPC25 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HELLS NUF2 CDCA5
GO:0030894	CC	replisome	0.142857142857143	0.305624922751063	14	5.54699037247534	POLA1 RPA3 PRIM1
GO:0043601	CC	nuclear replisome	0.142857142857143	0.305624922751063	14	5.54699037247534	POLA1 RPA3 PRIM1
GO:0000793	CC	condensed chromosome	0.141509433962264	0.330753197707753	53	10.6972314174982	TOPBP1 RAD51 SYCP2 BUB1B SMC2 CENPE CHEK1 BLM CENPF
GO:0007088	BP	regulation of mitosis	0.1375	0.320006009558955	40	9.00820808267969	ANLN BIRC5 NEK2 NUSAP1 DLG7 MPHOSPH1 KNTC1
GO:0008094	MF	DNA-dependent ATPase activity	0.137254901960784	0.31746545280627	51	10.1558290339839	MCM6 RAD51 MCM4 MCM8 TOP2A MCM5 MCM2 RFC4 BLM
GO:0000077	BP	DNA damage checkpoint	0.134615384615385	0.333397429734913	26	7.09643912606599	CCNA2 CHEK1 BLM TIPIN
GO:0000278	BP	mitotic cell cycle	0.133663366336634	0.329743195599635	303	24.255319592796	ANLN BIRC5 POLA1 STMN1 CCNA2 NEK2 KIF23 KIF2C CDCA3 CDKN3 NUSAP1 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 SMC2 DBF4 KIF11 CDC7 TTK CENPE MPHOSPH1 CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 SPC25 NCAPH CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HELLS NUF2 CDCA5
GO:0000226	BP	microtubule cytoskeleton organization and biogenesis	0.129213483146067	0.324458376372004	89	12.5898844867250	STMN1 KIF23 KIF2C NUSAP1 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK PRC1
GO:0000279	BP	M phase	0.128252788104089	0.322219905038498	269	21.8379978712431	ANLN BIRC5 CCNA2 NEK2 KIF23 RAD51 SYCP2 KIF2C CDCA3 NUSAP1 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 CKS2 SMC2 KIF11 CENPE MPHOSPH1 CHEK1 KNTC1 CENPF SPC25 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HELLS NUF2 MND1 CDCA5
GO:0008637	BP	apoptotic mitochondrial changes	0.125	0.341565025531987	16	5.13906652483733	BID CDKN2A
GO:0000080	BP	G1 phase of mitotic cell cycle	0.125	0.341565025531987	16	5.13906652483733	CDC2 CDC6
GO:0043596	CC	nuclear replication fork	0.125	0.288675134594813	16	5.13906652483733	POLA1 RPA3 PRIM1
GO:0006261	BP	DNA-dependent DNA replication	0.123711340206186	0.306449151531256	97	12.5450258620493	POLA1 MCM6 RAD51 CCNE2 MCM4 MCM8 MCM5 MCM2 CDC6 RFC4 CDC45L PRIM1 BLM CDT1 TIPIN
GO:0022403	BP	cell cycle phase	0.123493975903614	0.317832286750992	332	23.3397422694113	ANLN BIRC5 POLA1 CCNA2 NEK2 KIF23 RAD51 SYCP2 KIF2C CDCA3 CDKN3 NUSAP1 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 CKS2 SMC2 DBF4 KIF11 CDC7 CENPE MPHOSPH1 CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 SPC25 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HELLS NUF2 MND1 CDCA5
GO:0006260	BP	DNA replication	0.120603015075377	0.30654088031451	199	17.5384123408372	GINS2 POLA1 MCM6 FEN1 RAD51 CCNE2 POLQ RPA3 MCM4 MCM8 TOP2A MCM5 RRM2 MCM2 RNASEH2A CDC6 RFC4 CDC45L DBF4 PRIM1 BLM POLE2 GINS1 CDT1 DNA2 DTL ORC6L TIPIN MCM10
GO:0000795	CC	synaptonemal complex	0.115384615384615	0.299572344757639	13	4.2478266329858	SYCP2 BLM
GO:0022402	BP	cell cycle process	0.113691931540342	0.307038850703951	409	23.7460093529829	ANLN BIRC5 POLA1 STMN1 CCNA2 NEK2 KIF23 RAD51 SYCP2 KIF2C CDCA3 CDKN3 NUSAP1 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 CKS2 SMC2 DBF4 KIF11 CDC7 MLF1 TTK CENPE MPHOSPH1 BARD1 CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 SPC25 NCAPH CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HELLS NUF2 MND1 CDCA5 C11orf82
GO:0000794	CC	condensed nuclear chromosome	0.112903225806452	0.280168919860705	31	6.41018657040956	TOPBP1 RAD51 SYCP2 CHEK1 BLM
GO:0051318	BP	G1 phase	0.111111111111111	0.323380833381777	18	4.79832518791249	CDC2 CDC6
GO:0000152	CC	nuclear ubiquitin ligase complex	0.111111111111111	0.323380833381777	18	4.79832518791249	BUB1B BARD1
GO:0044427	CC	chromosomal part	0.109929078014184	0.298824497592524	282	18.9309798001735	SUV39H2 BIRC5 POLA1 CENPA SYCP2 KIF2C RPA3 MLF1IP CENPQ CENPO MYBL2 MCM2 BUB1B RFC4 ZWINT NDC80 SMC2 NEFH CENPE PRIM1 CHEK1 BLM CENPF CDT1 SPC25 ASF1B ZWILCH ORC6L TIPIN CENPN HELLS CENPK NUF2 CDCA5 SGOL2 CENPH
GO:0007127	BP	meiosis I	0.103448275862069	0.279646152205514	29	5.63527936046008	RAD51 SYCP2 CKS2 CHEK1
GO:0000228	CC	nuclear chromosome	0.102150537634409	0.281293013956612	93	9.973054101087	POLA1 TOPBP1 RAD51 SYCP2 RPA3 MCM2 SMC2 PRIM1 CHEK1 BLM ORC6L TIPIN
GO:0044454	CC	nuclear chromosome part	0.1015625	0.284237876847757	64	8.21346037658308	POLA1 SYCP2 RPA3 MCM2 PRIM1 BLM ORC6L TIPIN
GO:0005694	CC	chromosome	0.100591715976331	0.286075884066666	338	18.8416184678968	SUV39H2 BIRC5 POLA1 TOPBP1 CENPA RAD51 SYCP2 KIF2C RPA3 MLF1IP CENPQ CENPO TOP2A MYBL2 MCM2 BUB1B RFC4 ZWINT NDC80 SMC2 NEFH CENPE PRIM1 CHEK1 BLM CENPF CDT1 SPC25 FANCI ASF1B ZWILCH ORC6L TIPIN CENPN HELLS CENPK NUF2 CDCA5 SGOL2 CENPH
GO:0006302	BP	double-strand break repair	0.1	0.265684465662029	35	5.96589618505855	POLA1 FEN1 RAD51 RAD51AP1 BLM
GO:0030262	BP	apoptotic nuclear changes	0.1	0.307793505625546	20	4.50765549527706	TOP2A CDKN2A
GO:0016605	CC	PML body	0.1	0.261574181890298	20	4.50765549527706	TOPBP1 RAD51 BLM
GO:0003777	MF	microtubule motor activity	0.1	0.291221782465321	80	9.03245255310511	KIF23 KIF2C KIF11 CENPE MPHOSPH1 KIF14 KIF4A KIF20A KIF15
GO:0006323	BP	DNA packaging	0.099056603773585	0.296164459788289	106	10.2978120777333	CENPA NUSAP1 TOP2A MCM2 SMC2 NEFH NCAPH ASF1B NCAPG HELLS CDCA5
GO:0000910	BP	cytokinesis	0.0967741935483871	0.271396230590063	31	5.41487529648396	ANLN BIRC5 NUSAP1 PRC1
GO:0051052	BP	regulation of DNA metabolic process	0.0964912280701754	0.290298437745355	57	7.32486527507205	RAD51 CDC6 CDC45L BLM CDT1 TIPIN
GO:0045787	BP	positive regulation of cell cycle	0.0961538461538462	0.283521807599725	26	4.92316536055566	BIRC5 NUSAP1 DLG7
GO:0051726	BP	regulation of cell cycle	0.0907473309608541	0.279897577316228	281	15.3044839934457	ANLN BIRC5 CCNA2 NEK2 CCNE2 CDKN3 NUSAP1 CDC2 BUB1B DLG7 CDC6 ZWINT CDC45L CKS2 CDC7 TTK MPHOSPH1 CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 ZWILCH FBXO5 TIPIN HERC5 CABLES2
GO:0048015	BP	phosphoinositide-mediated signaling	0.09	0.278705521432152	100	8.99424364721111	FEN1 P2RY1 TOP2A SPAG5 BUB1B RFC4 ZWINT AURKA NDC80 CKS2
GO:0007017	BP	microtubule-based process	0.0879396984924623	0.277170545868204	199	12.4041733140353	STMN1 KIF23 KIF2C NUSAP1 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK CENPE MPHOSPH1 KIF14 PRC1 KIF4A KIF20A KIF15
GO:0016891	MF	endoribonuclease activity, producing 5'-phosphomonoesters	0.0869565217391304	0.245513095051765	23	4.14124620046381	FEN1 DBR1 RNASEH2A
GO:0003697	MF	single-stranded DNA binding	0.0851063829787234	0.240451317864385	47	5.78376761882388	MCM6 RAD51 RPA3 MCM4 RAD51AP1 BLM
GO:0007018	BP	microtubule-based movement	0.0833333333333333	0.268197361212603	96	8.08595180502489	KIF23 KIF2C KIF11 CENPE MPHOSPH1 KIF14 KIF4A KIF20A KIF15
GO:0007049	BP	cell cycle	0.0817039106145251	0.263038515165004	716	22.0366361922134	ANLN CKAP2 SUV39H2 BIRC5 POLA1 STMN1 MCM6 CCNA2 NEK2 KIF23 RAD51 CCNE2 SYCP2 KIF2C CDCA3 MCM8 E2F7 CDKN3 NUSAP1 MCM2 SPAG5 CDC2 BUB1B DLG7 CDC6 ZWINT AURKA CDC45L NDC80 CKS2 SMC2 DBF4 KIF11 CDC7 MLF1 TTK CENPE MPHOSPH1 BARD1 CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 HERC5 E2F8 HELLS NUF2 MND1 CDCA5 UHRF1 CABLES2 C11orf82 SGOL2
GO:0042770	BP	DNA damage response, signal transduction	0.0777777777777778	0.260147588258603	45	5.11389577002573	CCNA2 CHEK1 BLM TIPIN
GO:0016363	CC	nuclear matrix	0.0760869565217391	0.257496306431931	46	5.04340769746737	POLA1 BLM CENPF KIF4A
GO:0007050	BP	cell cycle arrest	0.073170731707317	0.262019121198305	82	6.44820358997258	CDKN3 MLF1 MPHOSPH1 BARD1 CDKN2A C11orf82
GO:0006259	BP	DNA metabolic process	0.0731441048034935	0.248847111890939	458	15.4179762358162	GINS2 POLA1 TOPBP1 MCM6 FEN1 RAD51 CCNE2 POLQ RPA3 MCM4 MCM8 TOP2A MCM5 RRM2 MCM2 RNASEH2A CDC6 RFC4 CDC45L RAD51AP1 SMC2 DBF4 PRIM1 CHEK1 BLM POLE2 GINS1 CDKN2A CDT1 FANCI DNA2 DTL ORC6L TIPIN DCLRE1B HELLS MCM10 MND1 UHRF1
GO:0030705	BP	cytoskeleton-dependent intracellular transport	0.0689655172413793	0.245804373648940	116	7.1743401885193	KIF23 KIF2C KIF11 CENPE MPHOSPH1 KIF14 KIF4A KIF20A KIF15
GO:0005875	CC	microtubule associated complex	0.0683760683760684	0.244825614450992	117	7.13456810306203	KIF23 KIF2C KIF11 CENPE MPHOSPH1 KIF14 KIF4A KIF20A KIF15
GO:0005874	CC	microtubule	0.0665137614678899	0.237939992228955	218	9.46359801501749	CKAP2 BIRC5 STMN1 KIF23 KIF2C NUSAP1 SPAG5 CDC2 KIF11 CENPE MPHOSPH1 KNTC1 KIF14 PRC1 KIF4A KIF20A KIF15
GO:0007126	BP	meiosis	0.0652173913043478	0.225457761112887	69	5.17947872435025	NEK2 RAD51 SYCP2 CKS2 CHEK1 MND1
GO:0051327	BP	M phase of meiotic cell cycle	0.0652173913043478	0.225457761112887	69	5.17947872435025	NEK2 RAD51 SYCP2 CKS2 CHEK1 MND1
GO:0015630	CC	microtubule cytoskeleton	0.0638297872340425	0.236463302897133	376	11.9086924336524	CKAP2 BIRC5 STMN1 NEK2 KIF23 KIF2C NUSAP1 TOP2A SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA KIF11 TTK CENPE MPHOSPH1 KNTC1 KIF14 CENPF CCNB1 PRC1 KIF4A KIF20A FBXO5 KIF15
GO:0051321	BP	meiotic cell cycle	0.0633802816901408	0.222479171814685	71	5.08255601875261	NEK2 RAD51 SYCP2 CKS2 CHEK1 MND1
GO:0003682	MF	chromatin binding	0.0611111111111111	0.222697681125168	90	5.48675808794337	SUV39H2 POLA1 CENPA TOP2A CDC6 CENPF CDCA5
GO:0003774	MF	motor activity	0.0598591549295775	0.226618640872215	142	6.73736638625573	KIF23 KIF2C MYO5C KIF11 CENPE MPHOSPH1 KIF14 KIF4A KIF20A KIF15
GO:0031497	BP	chromatin assembly	0.0576923076923077	0.22764704439807	78	4.77080066085991	CENPA MCM2 NEFH ASF1B HELLS
GO:0051276	BP	chromosome organization and biogenesis	0.0568181818181818	0.225595990419934	352	10.0403998932053	SUV39H2 EZH2 CENPA SYCP2 NUSAP1 TOP2A MCM2 HLTF DLG7 ZWINT NDC80 SMC2 NEFH CENPE BLM CENPF NCAPH ASF1B NCAPG HELLS CDCA5 CENPH
GO:0000785	CC	chromatin	0.0555555555555556	0.218815257601165	153	6.40362186997008	SUV39H2 POLA1 CENPA MYBL2 MCM2 NEFH CENPF ASF1B TIPIN HELLS
GO:0005813	CC	centrosome	0.0534351145038168	0.217077692551862	131	5.65138021872325	BIRC5 NEK2 TOP2A DLG7 AURKA MPHOSPH1 CCNB1 KIF15
GO:0006974	BP	response to DNA damage stimulus	0.0514950166112957	0.207780551243573	301	8.23691284447461	POLA1 TOPBP1 CCNA2 FEN1 RAD51 POLQ RPA3 TOP2A RFC4 RAD51AP1 BARD1 CHEK1 BLM POLE2 FANCI DTL TIPIN DCLRE1B UHRF1
GO:0005815	CC	microtubule organizing center	0.05	0.210344014216109	140	5.39192087601729	BIRC5 NEK2 TOP2A DLG7 AURKA MPHOSPH1 CCNB1 KIF15
GO:0006281	BP	DNA repair	0.0489795918367347	0.201553850124062	245	6.97857642803944	POLA1 TOPBP1 FEN1 RAD51 POLQ RPA3 TOP2A RFC4 RAD51AP1 CHEK1 BLM POLE2 FANCI DCLRE1B UHRF1
GO:0043566	MF	structure-specific DNA binding	0.0489130434782609	0.182470569788629	92	4.24848529766747	MCM6 FEN1 RAD51 RPA3 MCM4 RAD51AP1 BLM
GO:0006310	BP	DNA recombination	0.046875	0.206195168150035	96	4.11863681808027	RAD51 RAD51AP1 CHEK1 BLM MND1
GO:0044430	CC	cytoskeletal part	0.0424143556280587	0.193426392215085	613	9.33550028774925	ANLN CKAP2 BIRC5 STMN1 NEK2 KIF23 KIF2C MYO5C NUSAP1 TOP2A SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA NEFH KIF11 TTK CENPE MPHOSPH1 KNTC1 KIF14 CENPF CCNB1 PRC1 KIF4A KIF20A FBXO5 KIF15
GO:0006333	BP	chromatin assembly or disassembly	0.0423728813559322	0.191443807854905	118	4.02590182729892	SUV39H2 CENPA MCM2 NEFH ASF1B HELLS
GO:0009719	BP	response to endogenous stimulus	0.0399484536082474	0.184200198421114	388	6.82837736943878	POLA1 TOPBP1 CCNA2 FEN1 RAD51 POLQ RPA3 TOP2A RFC4 RAD51AP1 BARD1 CHEK1 BLM POLE2 FANCI DTL TIPIN DCLRE1B UHRF1
GO:0019932	BP	second-messenger-mediated signaling	0.0386266094420601	0.187455287944994	233	5.04010203329133	FEN1 P2RY1 TOP2A SPAG5 BUB1B RFC4 ZWINT AURKA NDC80 CKS2
GO:0007010	BP	cytoskeleton organization and biogenesis	0.0378947368421053	0.185542281605514	475	7.073397293324	ANLN STMN1 KIF23 KIF2C NUSAP1 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK CENPE MPHOSPH1 KIF14 PRC1 KIF4A KIF20A KIF15
GO:0045859	BP	regulation of protein kinase activity	0.0350877192982456	0.178334169389570	228	4.38895898901565	CCNA2 CCNE2 CDKN3 CDC6 CKS2 CHEK1 BLM CDKN2A HERC5
GO:0043228	CC	non-membrane-bound organelle	0.034388314059647	0.174164195589545	1643	12.023349870298	ANLN CKAP2 SUV39H2 BIRC5 POLA1 TOPBP1 STMN1 NEK2 KIF23 CENPA RAD51 SYCP2 LOC81691 KIF2C RPA3 MLF1IP MYO5C CENPQ CENPO NUSAP1 TOP2A MYBL2 MCM2 SPAG5 CDC2 BUB1B DLG7 CDC6 RFC4 ZWINT AURKA NDC80 SMC2 NEFH KIF11 TTK CENPE PRIM1 MPHOSPH1 CHEK1 BLM KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 FANCI CCNB1 PRC1 ASF1B ZWILCH KIF4A KIF20A FBXO5 ORC6L TIPIN KIF15 CENPN HELLS CENPK NUF2 CDCA5 SGOL2 CENPH
GO:0043232	CC	intracellular non-membrane-bound organelle	0.034388314059647	0.174164195589545	1643	12.023349870298	ANLN CKAP2 SUV39H2 BIRC5 POLA1 TOPBP1 STMN1 NEK2 KIF23 CENPA RAD51 SYCP2 LOC81691 KIF2C RPA3 MLF1IP MYO5C CENPQ CENPO NUSAP1 TOP2A MYBL2 MCM2 SPAG5 CDC2 BUB1B DLG7 CDC6 RFC4 ZWINT AURKA NDC80 SMC2 NEFH KIF11 TTK CENPE PRIM1 MPHOSPH1 CHEK1 BLM KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 FANCI CCNB1 PRC1 ASF1B ZWILCH KIF4A KIF20A FBXO5 ORC6L TIPIN KIF15 CENPN HELLS CENPK NUF2 CDCA5 SGOL2 CENPH
GO:0043549	BP	regulation of kinase activity	0.0343347639484979	0.176475575730360	233	4.30932690687339	CCNA2 CCNE2 CDKN3 CDC6 CKS2 CHEK1 BLM CDKN2A HERC5
GO:0051338	BP	regulation of transferase activity	0.0336134453781513	0.174673806143441	238	4.23186653693488	CCNA2 CCNE2 CDKN3 CDC6 CKS2 CHEK1 BLM CDKN2A HERC5
GO:0006996	BP	organelle organization and biogenesis	0.0333024976873266	0.174273917225835	1081	9.15562983689246	ANLN SUV39H2 STMN1 EZH2 KIF23 CENPA SYCP2 KIF2C NUSAP1 TOP2A MCM2 HLTF SPAG5 BUB1B DLG7 ZWINT AURKA NDC80 CKS2 SMC2 NEFH KIF11 BID TTK CENPE MPHOSPH1 BLM KIF14 CDKN2A CENPF NCAPH PRC1 ASF1B KIF4A NCAPG KIF20A KIF15 HELLS CDCA5 CENPH
GO:0016887	MF	ATPase activity	0.0300632911392405	0.159008822099041	316	4.18264822991316	MCM6 RAD51 POLQ MCM4 MCM8 TOP2A MCM5 MCM2 HLTF RFC4 MPHOSPH1 BLM
GO:0005524	MF	ATP binding	0.0288611544461778	0.160337605582252	1282	8.20248928156051	HSPA6 FIGNL1 SLFN13 MCM6 NEK2 KIF23 RAD51 POLQ KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0032559	MF	adenyl ribonucleotide binding	0.0284615384615385	0.159258585987922	1300	8.09846843969716	HSPA6 FIGNL1 SLFN13 MCM6 NEK2 KIF23 RAD51 POLQ KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0008283	BP	cell proliferation	0.0281207133058985	0.162287584656241	729	5.8445195110746	POLA1 KIF2C CDCA7 CDKN3 BUB1B DLG7 CDC6 CKS2 CDC7 TTK CHEK1 LAMP3 BLM GINS1 CDKN2A CENPF MKI67 TIPIN KIF15 HELLS TCF19 UHRF1
GO:0030554	MF	adenyl nucleotide binding	0.0269286754002911	0.155040673211055	1374	7.68871135992241	HSPA6 FIGNL1 SLFN13 MCM6 NEK2 KIF23 RAD51 POLQ KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0005856	CC	cytoskeleton	0.0260521042084168	0.152947127341009	998	6.15250370042441	ANLN CKAP2 BIRC5 STMN1 NEK2 KIF23 KIF2C MYO5C NUSAP1 TOP2A SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA NEFH KIF11 TTK CENPE MPHOSPH1 KNTC1 KIF14 CENPF CCNB1 PRC1 KIF4A KIF20A FBXO5 KIF15
GO:0032553	MF	ribonucleotide binding	0.0228818800247372	0.14323302527398	1617	6.51041615464653	HSPA6 FIGNL1 SLFN13 MCM6 NEK2 KIF23 RAD51 POLQ KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0032555	MF	purine ribonucleotide binding	0.0228818800247372	0.14323302527398	1617	6.51041615464653	HSPA6 FIGNL1 SLFN13 MCM6 NEK2 KIF23 RAD51 POLQ KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0044428	CC	nuclear part	0.0226130653266332	0.140926818737912	995	4.90189732436352	POLA1 TOPBP1 EZH2 RAD51 SYCP2 POLQ LOC81691 RPA3 E2F7 TOP2A MCM2 BUB1B SMC2 WDHD1 PRIM1 MPHOSPH1 BARD1 CHEK1 BLM CDKN2A CENPF MKI67 KIF4A NUP107 ORC6L TIPIN E2F8
GO:0017076	MF	purine nucleotide binding	0.0218546958062611	0.140059461062358	1693	6.18434377550037	HSPA6 FIGNL1 SLFN13 MCM6 NEK2 KIF23 RAD51 POLQ KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0005634	CC	nucleus	0.0207701283547258	0.13635533522924	4285	9.96587648753944	ANLN SUV39H2 BIRC5 GINS2 POLA1 TOPBP1 MCM6 KIAA0101 EZH2 CCNA2 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP DBR1 CENPQ CENPO MCM8 CDCA7 E2F7 ZNF367 NUSAP1 TOP2A MYBL2 MCM5 MCM2 FOXM1 HLTF RNASEH2A CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH CDC7 WDHD1 MLF1 CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B KIF4A DTL NCAPG NUP107 FBXO5 RMI1 ORC6L TIPIN DCLRE1B CENPN E2F8 HELLS MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 C11orf82 SGOL2 CENPH
GO:0044446	CC	intracellular organelle part	0.0198388096714197	0.133213492089719	3226	7.61996741621703	ANLN CKAP2 SUV39H2 BIRC5 POLA1 TOPBP1 STMN1 EZH2 NEK2 KIF23 CENPA RAD51 SYCP2 POLQ LOC81691 KIF2C RPA3 MLF1IP MYO5C CENPQ CENPO E2F7 NUSAP1 TOP2A MYBL2 MCM2 SPAG5 CDC2 BUB1B DLG7 CDC6 RFC4 ZWINT AURKA NDC80 SMC2 NEFH KIF11 BID WDHD1 TTK CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 CCNB1 PRC1 ASF1B ZWILCH KIF4A KIF20A NUP107 FBXO5 ORC6L TIPIN KIF15 CENPN SLC15A3 E2F8 HELLS CENPK NUF2 CDCA5 SGOL2 CENPH
GO:0044422	CC	organelle part	0.0197775030902349	0.133011997927445	3236	7.59150660467721	ANLN CKAP2 SUV39H2 BIRC5 POLA1 TOPBP1 STMN1 EZH2 NEK2 KIF23 CENPA RAD51 SYCP2 POLQ LOC81691 KIF2C RPA3 MLF1IP MYO5C CENPQ CENPO E2F7 NUSAP1 TOP2A MYBL2 MCM2 SPAG5 CDC2 BUB1B DLG7 CDC6 RFC4 ZWINT AURKA NDC80 SMC2 NEFH KIF11 BID WDHD1 TTK CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 CCNB1 PRC1 ASF1B ZWILCH KIF4A KIF20A NUP107 FBXO5 ORC6L TIPIN KIF15 CENPN SLC15A3 E2F8 HELLS CENPK NUF2 CDCA5 SGOL2 CENPH
GO:0000166	MF	nucleotide binding	0.0195172059578839	0.131710125386361	1947	5.47297957813581	HSPA6 FIGNL1 SLFN13 POLA1 MCM6 NEK2 KIF23 RAD51 POLQ LOC81691 KIF2C MCM4 MYO5C MCM8 TOP2A MCM5 MCM2 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 KIF11 CDC7 TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 MKI67 DNA2 KIF4A KIF20A ATAD2 KIF15 HELLS SLFN11 MASTL
GO:0016043	BP	cellular component organization and biogenesis	0.0181582360570687	0.129440762268613	2313	5.26230441859547	ANLN SUV39H2 BIRC5 STMN1 EZH2 KIF23 CENPA RAD51 SYCP2 KIF2C NUSAP1 TOP2A CD14 MCM2 HLTF SPAG5 BUB1B DLG7 ZWINT AURKA NDC80 CKS2 SMC2 NEFH KIF11 BID TTK CENPE MPHOSPH1 BARD1 LY75 BLM KNTC1 KIF14 CDKN2A CENPF NCAPH PRC1 ASF1B KIF4A NCAPG KIF20A NUP107 KIF15 HELLS CDCA5 CENPH
GO:0003677	MF	DNA binding	0.0165641268338855	0.120014707828176	2113	4.12132776070158	POLA1 TOPBP1 C16orf75 MCM6 EZH2 FEN1 CENPA RAD51 SYCP2 POLQ KIF2C RPA3 MCM4 MCM8 E2F7 ZNF367 NUSAP1 TOP2A MYBL2 MCM5 MCM2 FOXM1 HLTF RFC4 RAD51AP1 NEFH WDHD1 MLF1 BLM POLE2 ISL1 CDKN2A CDT1 DNA2 KIF4A ORC6L KIF15 E2F8 HELLS TCF19 ZIC2 MND1 UHRF1
GO:0006139	BP	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0150887573964497	0.115696832882450	3380	4.40023143527798	FIGNL1 SUV39H2 GINS2 POLA1 TOPBP1 MCM6 EZH2 CCNA2 FEN1 RAD51 CCNE2 POLQ RPA3 MCM4 MLF1IP DBR1 MCM8 CDCA7 E2F7 ZNF367 TOP2A MYBL2 MCM5 RRM2 MCM2 DHFR FOXM1 HLTF RNASEH2A CDC6 RFC4 TRIP13 CDC45L RAD51AP1 SMC2 DBF4 WDHD1 MLF1 PRIM1 BARD1 CHEK1 BLM POLE2 GINS1 ISL1 CDKN2A CENPF CDT1 FANCI DNA2 ASF1B DTL ORC6L TIPIN DCLRE1B E2F8 HELLS MCM10 TCF19 MND1 UHRF1
GO:0043231	CC	intracellular membrane-bound organelle	0.0140792049390152	0.112764811717918	6641	5.98273596690506	ANLN SUV39H2 BIRC5 GINS2 POLA1 TOPBP1 MCM6 KIAA0101 EZH2 CCNA2 APOC1 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP DBR1 CENPQ CENPO MCM8 CDCA7 E2F7 ZNF367 NUSAP1 TOP2A MYBL2 MCM5 MCM2 FOXM1 HLTF RNASEH2A CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH BID CDC7 WDHD1 MLF1 CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B KIF4A DTL NCAPG KIF20A NUP107 FBXO5 RMI1 ORC6L TIPIN DCLRE1B CENPN SLC15A3 E2F8 HELLS MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 C11orf82 SGOL2 CENPH
GO:0043227	CC	membrane-bound organelle	0.0140749661297606	0.11274809751813	6643	5.9792672356354	ANLN SUV39H2 BIRC5 GINS2 POLA1 TOPBP1 MCM6 KIAA0101 EZH2 CCNA2 APOC1 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP DBR1 CENPQ CENPO MCM8 CDCA7 E2F7 ZNF367 NUSAP1 TOP2A MYBL2 MCM5 MCM2 FOXM1 HLTF RNASEH2A CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH BID CDC7 WDHD1 MLF1 CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B KIF4A DTL NCAPG KIF20A NUP107 FBXO5 RMI1 ORC6L TIPIN DCLRE1B CENPN SLC15A3 E2F8 HELLS MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 C11orf82 SGOL2 CENPH
GO:0043229	CC	intracellular organelle	0.0133155792276964	0.109581245131132	7510	5.67531831923957	ANLN CKAP2 SUV39H2 BIRC5 GINS2 POLA1 TOPBP1 STMN1 MCM6 KIAA0101 EZH2 CCNA2 APOC1 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP MYO5C DBR1 CENPQ CENPO MCM8 CDCA7 E2F7 ZNF367 NUSAP1 TOP2A MYBL2 MCM5 MCM2 FOXM1 HLTF RNASEH2A SPAG5 CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH KIF11 BID CDC7 WDHD1 MLF1 TTK CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B ZWILCH KIF4A DTL NCAPG KIF20A NUP107 FBXO5 RMI1 ORC6L TIPIN KIF15 DCLRE1B CENPN SLC15A3 E2F8 HELLS MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 C11orf82 SGOL2 CENPH
GO:0043226	CC	organelle	0.0133102622121656	0.109559684729112	7513	5.67043638698845	ANLN CKAP2 SUV39H2 BIRC5 GINS2 POLA1 TOPBP1 STMN1 MCM6 KIAA0101 EZH2 CCNA2 APOC1 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP MYO5C DBR1 CENPQ CENPO MCM8 CDCA7 E2F7 ZNF367 NUSAP1 TOP2A MYBL2 MCM5 MCM2 FOXM1 HLTF RNASEH2A SPAG5 CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH KIF11 BID CDC7 WDHD1 MLF1 TTK CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B ZWILCH KIF4A DTL NCAPG KIF20A NUP107 FBXO5 RMI1 ORC6L TIPIN KIF15 DCLRE1B CENPN SLC15A3 E2F8 HELLS MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 C11orf82 SGOL2 CENPH
GO:0044424	CC	intracellular part	0.0119231618458821	0.103602067430689	9058	4.66516405025946	ANLN KIAA1524 CKAP2 SUV39H2 BIRC5 HMMR GINS2 POLA1 TOPBP1 STMN1 MCM6 KIAA0101 EZH2 CCNA2 APOC1 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP MYO5C DBR1 CENPQ CENPO CDCA3 MCM8 CDCA7 MTPN E2F7 ZNF367 IFI44 NUSAP1 TOP2A MYBL2 MCM5 RRM2 MCM2 FOXM1 HLTF RNASEH2A SPAG5 CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH KIF11 BID CDC7 WDHD1 MLF1 TTK MELK CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B ZWILCH KIF4A DTL NCAPG KIF20A NUP107 FBXO5 RMI1 ORC6L TIPIN KIF15 DCLRE1B CENPN SLC15A3 HERC5 GIPC2 E2F8 HELLS MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 HYLS1 C11orf82 SGOL2 CENPH
GO:0005622	CC	intracellular	0.0118081180811808	0.102775429891296	9485	4.73572496657266	ANLN SLFN13 KIAA1524 CKAP2 SUV39H2 BIRC5 HMMR GINS2 POLA1 SYDE2 TOPBP1 STMN1 MCM6 KIAA0101 EZH2 CCNA2 APOC1 NEK2 KIF23 FEN1 CENPA RAD51 CCNE2 SYCP2 POLQ LOC81691 KIF2C RPA3 MCM4 MLF1IP MYO5C DBR1 CENPQ CENPO CDCA3 MCM8 CDCA7 MTPN TRIM59 E2F7 ZNF367 RTKN2 IFI44 NUSAP1 TOP2A MYBL2 MCM5 RRM2 MCM2 FOXM1 HLTF RNASEH2A SPAG5 CDC2 BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH KIF11 BID CDC7 WDHD1 MLF1 TTK MELK CENPE PRIM1 MPHOSPH1 BARD1 CHEK1 LAMP3 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 CDKN2A CENPF CDT1 SPC25 MKI67 NCAPH FANCI CCNB1 PRC1 ASF1B ZWILCH KIF4A DTL NCAPG KIF20A NUP107 FBXO5 RMI1 ORC6L TIPIN KIF15 DCLRE1B CENPN SLC15A3 HERC5 GIPC2 E2F8 HELLS DEPDC1 MCM10 DONSON CENPK TCF19 NUF2 ZIC2 MND1 CDCA5 UHRF1 SLFN11 C6orf173 HYLS1 PLEKHG4 C11orf82 SGOL2 CENPH
GO:0031224	CC	intrinsic to membrane	0.00332005312084993	0.0555731685719728	4518	-5.02284873018139	KIAA1524 P2RY1 FLRT3 TRIM59 HS6ST2 CLEC2B CD14 LAMP3 LY75 SYNGR3 ADAMDEC1 TMEM97 NUP107 NETO2 SLC15A3 ZIC2 TMEM71
GO:0016021	CC	integral to membrane	0.00316455696202532	0.0541217596355505	4424	-5.08471131067636	KIAA1524 P2RY1 FLRT3 TRIM59 HS6ST2 CLEC2B LAMP3 LY75 SYNGR3 ADAMDEC1 TMEM97 NUP107 NETO2 SLC15A3 ZIC2 TMEM71
GO:0044425	CC	membrane part	0.00292568753657109	0.052178665061337	5127	-5.88078656561772	KIAA1524 P2RY1 FLRT3 TRIM59 HS6ST2 CLEC2B CD14 LAMP3 LY75 SYNGR3 ADAMDEC1 TMEM97 NUP107 NETO2 SLC15A3 ZIC2 TMEM71
GO:0016020	CC	membrane	0.00290023201856148	0.0518180107584698	6034	-6.69605234184003	KIAA1524 POLA1 P2RY1 FLRT3 TRIM59 HS6ST2 CLEC2B CD14 BID LAMP3 LY75 SYNGR3 ADAMDEC1 CENPF TMEM97 NUP107 NETO2 SLC15A3 ZIC2 TMEM71
GO:0005886	CC	plasma membrane	0.0022271714922049	0.0451372333778018	2694	-4.28898029622312	P2RY1 FLRT3 CLEC2B CD14 LY75 SYNGR3 ZIC2