GOname	GO	GO.term	set.means	set.sd	n.genes	z.score	lead.genes
GO:0044238	BP	primary metabolic process	0.0199538971329780	0.126460565123203	6941	4.09971312168048	TAF2 CBX3 TARDBP DMRTA2 AHCTF1 ABCF1 ILF2 NONO RNPS1 SFRS2 SFRS10 SEPHS2 AARS STOM RBBP7 HDAC1 CACYBP PTDSS1 DDX23 DKC1 MCM3 ADAR PSRC1 ERCC3 CDK4 IRF1 CTPS UMPS ADM UBE2C HCLS1 HAT1 PAFAH1B3 PSMA4 AGL NFIL3 ZNF263 PPRC1 PARN TPST2 SLC7A7 PTPRN ZNF415 SNRPG DSG1 ALG3 ZNF304 SMPD4 PTPRH XPNPEP1 PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR INDO PLA2G4A B4GALT3 HMG2L1 POLR2I DDX12 PTPLAD1 LAP3 NIF3L1 NOL8 PFDN2 C16orf33 DUSP12 SCNM1 EIF2C3 ALG6 BANP CHIA DDX47 A1CF ACOT9 DOLPP1 TRMT5 DNAJB11 PLCD4 ZNFX1 CDCA7L DLX3 ZNF490 ZNF582 ACVR1C HAS3 C6orf151 TBK1 ZNF673 ENTPD3 RBM14 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 HPRT1 NCOA6 HNRPK RAD21 WARS PSAP DNAJA1 RPN1 COPB2 DHX15 SHC1 NCBP2 MBTPS1 GUSB PLOD2 TRRAP CUL2 MTRR DMTF1 ADNP2 PRPS2 RBP1 ALDH5A1 POLR2D HMGB3 MTR STK3 TUBB2A CHD1 TEAD4 TTF1 ASNS RECQL FBXO46 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 UCHL5IP DDX11 NCSTN MBD4 MAGOH AR YARS WEE1 EIF2C2 DHODH PMS2L1 ZNF20 MYCL1 SNX6 SUPT16H WBP11 USP39 BAZ1A TMEM48 DERL1 FANCL TOR3A MUS81 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 FGG ADPGK CHST6 CCDC101 TRMT6 MRPL47 SIN3A EEF2K ZBTB4 OMA1 LCOR NOM1 FBXL16 TOR2A ZNF776 ZNF439
GO:0006139	BP	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0251479289940828	0.140668536571856	3380	5.44949789913247	TAF2 CBX3 TARDBP DMRTA2 AHCTF1 ILF2 NONO RNPS1 SFRS2 SFRS10 AARS RBBP7 HDAC1 DDX23 DKC1 MCM3 ADAR PSRC1 ERCC3 IRF1 CTPS UMPS ADM HCLS1 NFIL3 ZNF263 PPRC1 PARN ZNF415 SNRPG ZNF304 PARP1 HMGN2 HARS2 ATR HMG2L1 POLR2I DDX12 NIF3L1 NOL8 C16orf33 SCNM1 EIF2C3 BANP DDX47 A1CF TRMT5 DNAJB11 ZNFX1 CDCA7L DLX3 ZNF490 ZNF582 C6orf151 ZNF673 ENTPD3 RBM14 EXOSC10 ZNF254 DNASE1L3 UPF2 SNRPB2 HPRT1 NCOA6 HNRPK RAD21 WARS DHX15 NCBP2 TRRAP DMTF1 ADNP2 PRPS2 POLR2D HMGB3 CHD1 TEAD4 TTF1 RECQL FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 MBD4 MAGOH AR YARS EIF2C2 DHODH PMS2L1 ZNF20 MYCL1 SNX6 SUPT16H WBP11 USP39 BAZ1A FANCL MUS81 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 CCDC101 TRMT6 SIN3A ZBTB4 LCOR NOM1 ZNF776 ZNF439
GO:0006396	BP	RNA processing	0.0494252873563218	0.196087046420264	435	6.3301528821019	TARDBP NONO RNPS1 SFRS2 SFRS10 AARS DDX23 DKC1 ADAR SNRPG C16orf33 SCNM1 A1CF TRMT5 C6orf151 EXOSC10 SNRPB2 HNRPK DHX15 NCBP2 SNRPA1 SFRS6 MAGOH WBP11 USP39 UTP6 TXNL4B RPP25 TRMT6
GO:0006399	BP	tRNA metabolic process	0.0660377358490566	0.229652653848343	106	4.62005790533063	AARS DKC1 HARS2 TRMT5 ZNFX1 WARS YARS RPP25 TRMT6
GO:0016070	BP	RNA metabolic process	0.0259328358208955	0.143865044894110	2680	5.1186574450439	TAF2 CBX3 TARDBP DMRTA2 ILF2 NONO RNPS1 SFRS2 SFRS10 AARS RBBP7 HDAC1 DDX23 DKC1 MCM3 ADAR PSRC1 ERCC3 IRF1 HCLS1 NFIL3 ZNF263 PPRC1 PARN ZNF415 SNRPG ZNF304 PARP1 HMGN2 HARS2 HMG2L1 POLR2I NIF3L1 C16orf33 SCNM1 BANP DDX47 A1CF TRMT5 DNAJB11 ZNFX1 CDCA7L DLX3 ZNF490 ZNF582 C6orf151 ZNF673 RBM14 EXOSC10 ZNF254 UPF2 SNRPB2 NCOA6 HNRPK WARS DHX15 NCBP2 TRRAP DMTF1 ADNP2 POLR2D HMGB3 CHD1 TEAD4 TTF1 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 MAGOH AR YARS ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A UTP6 UPF3B TXNL4B POLR3K CCDC59 RPP25 CCDC101 TRMT6 SIN3A ZBTB4 LCOR NOM1 ZNF776 ZNF439
GO:0043283	BP	biopolymer metabolic process	0.0219231604080747	0.132435813272564	4607	4.38625184682910	TAF2 CBX3 TARDBP DMRTA2 ILF2 NONO RNPS1 SFRS2 SFRS10 AARS RBBP7 HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR PSRC1 ERCC3 CDK4 IRF1 UBE2C HCLS1 HAT1 PSMA4 AGL NFIL3 ZNF263 PPRC1 PARN TPST2 PTPRN ZNF415 SNRPG ALG3 ZNF304 PTPRH PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 ATR HMG2L1 POLR2I PTPLAD1 NIF3L1 NOL8 C16orf33 DUSP12 SCNM1 ALG6 BANP CHIA DDX47 A1CF DOLPP1 TRMT5 DNAJB11 ZNFX1 CDCA7L DLX3 ZNF490 ZNF582 ACVR1C C6orf151 TBK1 ZNF673 RBM14 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 NCOA6 HNRPK RAD21 WARS RPN1 DHX15 SHC1 NCBP2 PLOD2 TRRAP CUL2 DMTF1 ADNP2 POLR2D HMGB3 STK3 CHD1 TEAD4 TTF1 RECQL FBXO46 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 UCHL5IP NCSTN MBD4 MAGOH AR YARS WEE1 PMS2L1 ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A DERL1 FANCL MUS81 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 CCDC101 TRMT6 SIN3A EEF2K ZBTB4 LCOR NOM1 FBXL16 ZNF776 ZNF439
GO:0032501	BP	multicellular organismal process	0.00822050290135396	0.0813866783594677	3102	-4.19793938058185	PCDH21 GAS7 HPRT1 NCOA6 TNFAIP2 NDUFV2 ALDH5A1 HMGB3 MTR TUBB2A TEAD4 C1orf107 DOPEY2 IFI16 OR2F1 AR COL9A2 FGG RGMA AHCTF1 RBBP7 NUDC ERCC3 IRF1 ADM HCLS1 PAFAH1B3 CRYM IQCB1 KRT32 ATR TNFRSF12A BANP CHIA DLX3
GO:0007166	BP	cell surface receptor linked signal transduction	0.00369549150036955	0.0542670537540921	1353	-4.14948906095315	SHC1 OR2F1 NCSTN SNX6 DEFB4 NUP85 LGR6
GO:0006397	BP	mRNA processing	0.062992125984252	0.222207092669466	254	6.74988403558948	TARDBP NONO RNPS1 SFRS2 SFRS10 DDX23 ADAR SNRPG C16orf33 SCNM1 A1CF C6orf151 SNRPB2 HNRPK DHX15 SNRPA1 SFRS6 MAGOH WBP11 USP39 TXNL4B
GO:0009451	BP	RNA modification	0.121212121212121	0.331433982639808	33	5.39707653663438	DKC1 ADAR PARN DNAJB11
GO:0016071	BP	mRNA metabolic process	0.0667808219178082	0.226642716335758	292	7.82791200762302	TARDBP NONO RNPS1 SFRS2 SFRS10 DDX23 ADAR PARN SNRPG C16orf33 SCNM1 A1CF DNAJB11 C6orf151 EXOSC10 UPF2 SNRPB2 HNRPK DHX15 SNRPA1 SFRS6 MAGOH WBP11 USP39 UPF3B TXNL4B
GO:0016553	BP	base conversion or substitution editing	0.25	0.5	4	4.17115015919865	ADAR
GO:0031047	BP	RNA-mediated gene silencing	0.192307692307692	0.383973823894152	13	5.66879515108785	ADAR EIF2C3 EIF2C2
GO:0042448	BP	progesterone metabolic process	0.25	0.5	4	4.17115015919865	ADM
GO:0006986	BP	response to unfolded protein	0.076271186440678	0.242358371760418	59	4.14293423943086	CCND1 TOR1B HSPA2 DNAJA1 VAPB DERL1
GO:0030968	BP	unfolded protein response	0.142857142857143	0.305624922751063	14	4.23468737510315	CCND1 VAPB DERL1
GO:0051789	BP	response to protein stimulus	0.076271186440678	0.242358371760418	59	4.14293423943086	CCND1 TOR1B HSPA2 DNAJA1 VAPB DERL1
GO:0031536	BP	positive regulation of exit from mitosis	0.25	0.5	4	4.17115015919865	UBE2C
GO:0006401	BP	RNA catabolic process	0.0888888888888889	0.24515507357795	45	4.37132179466683	RNPS1 PARN EXOSC10 UPF2 MAGOH UPF3B
GO:0006402	BP	mRNA catabolic process	0.137931034482759	0.295699887800655	29	5.861214109996	RNPS1 PARN EXOSC10 UPF2 MAGOH UPF3B
GO:0000097	BP	sulfur amino acid biosynthetic process	0.153846153846154	0.315212585978058	13	4.43346845335347	SEPHS2 MTRR MTR
GO:0006206	BP	pyrimidine base metabolic process	0.1875	0.372011904571422	8	4.32515202627457	UMPS DHODH
GO:0006207	BP	'de novo' pyrimidine base biosynthetic process	0.375	0.478713553878169	4	6.39753422941576	UMPS DHODH
GO:0006221	BP	pyrimidine nucleotide biosynthetic process	0.131578947368421	0.326688148237475	19	4.49603263503511	CTPS UMPS DHODH
GO:0019856	BP	pyrimidine base biosynthetic process	0.375	0.478713553878169	4	6.39753422941576	UMPS DHODH
GO:0046112	BP	nucleobase biosynthetic process	0.166666666666667	0.353553390593274	9	4.03097746121813	UMPS DHODH
GO:0008380	BP	RNA splicing	0.0668202764976959	0.223411118199405	217	6.73714162745007	TARDBP NONO RNPS1 SFRS2 SFRS10 DDX23 SNRPG C16orf33 SCNM1 C6orf151 SNRPB2 HNRPK DHX15 NCBP2 SNRPA1 SFRS6 MAGOH WBP11 USP39 TXNL4B
GO:0009218	BP	pyrimidine ribonucleotide metabolic process	0.15625	0.352077169571293	16	5.00462038150855	CTPS UMPS DHODH
GO:0009220	BP	pyrimidine ribonucleotide biosynthetic process	0.166666666666667	0.361873432227873	15	5.20495577947641	CTPS UMPS DHODH
GO:0018196	BP	peptidyl-asparagine modification	0.166666666666667	0.353553390593274	9	4.03097746121813	RPN2 RPN1
GO:0018279	BP	protein amino acid N-linked glycosylation via asparagine	0.166666666666667	0.353553390593274	9	4.03097746121813	RPN2 RPN1
GO:0000245	BP	spliceosome assembly	0.103448275862069	0.279646152205514	29	4.20619089305234	DDX23 SNRPG SFRS6 USP39
GO:0000375	BP	RNA splicing, via transesterification reactions	0.0746268656716418	0.234419517481780	67	4.2959028744795	SFRS10 DDX23 SNRPG SNRPB2 SNRPA1 SFRS6 USP39
GO:0000377	BP	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	0.0746268656716418	0.234419517481780	67	4.2959028744795	SFRS10 DDX23 SNRPG SNRPB2 SNRPA1 SFRS6 USP39
GO:0000398	BP	nuclear mRNA splicing, via spliceosome	0.0746268656716418	0.234419517481780	67	4.2959028744795	SFRS10 DDX23 SNRPG SNRPB2 SNRPA1 SFRS6 USP39
GO:0006458	BP	'de novo' protein folding	0.2	0.349602949390050	10	5.18806130366186	TOR1B TOR3A TOR2A
GO:0051084	BP	'de novo' posttranslational protein folding	0.2	0.349602949390050	10	5.18806130366186	TOR1B TOR3A TOR2A
GO:0051085	BP	chaperone cofactor-dependent protein folding	0.285714285714286	0.393397896234722	7	6.36000942315669	TOR1B TOR3A TOR2A
GO:0000184	BP	mRNA catabolic process, nonsense-mediated decay	0.190476190476190	0.334521691232066	21	7.13194988521531	RNPS1 PARN EXOSC10 UPF2 MAGOH UPF3B
GO:0045084	BP	positive regulation of interleukin-12 biosynthetic process	0.25	0.5	4	4.17115015919865	IRF1
GO:0045022	BP	early endosome to late endosome transport	0.25	0.5	4	4.17115015919865	ANKRD27
GO:0007047	BP	cell wall organization and biogenesis	0.133333333333333	0.351865775274498	15	4.05485655473101	CHIA LYSMD2
GO:0010382	BP	cell wall metabolic process	0.133333333333333	0.351865775274498	15	4.05485655473101	CHIA LYSMD2
GO:0009395	BP	phospholipid catabolic process	0.153846153846154	0.375533808099405	13	4.43346845335347	SMPD4 PLA2G4A
GO:0048496	BP	maintenance of organ identity	0.25	0.5	4	4.17115015919865	IQCB1
GO:0031958	BP	corticosteroid receptor signaling pathway	0.25	0.288675134594813	4	4.17115015919865	RBM14 NCOA6
GO:0042921	BP	glucocorticoid receptor signaling pathway	0.25	0.288675134594813	4	4.17115015919865	RBM14 NCOA6
GO:0005576	CC	extracellular region	0.00469483568075117	0.0591704312818675	1704	-4.32533714260158	PSAP TNFAIP2 BTC YARS COL9A2 FGG FAM20C TOR2A ADM DEFB4 IL15RA CHIA
GO:0005622	CC	intracellular	0.019082762256194	0.122597545507438	9485	4.47827837799487	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 TMEM49 ILF2 NONO RNPS1 LASP1 SFRS2 PSMD2 SFRS10 AARS STOM RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR GDI1 PSRC1 M6PRBP1 ERCC3 CDK4 IRF1 ADM HCLS1 HAT1 PAFAH1B3 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN TPST2 CRYM ZNF415 SNRPG KRT32 IL15RA ALG3 ZNF304 SMPD4 NVL ECOP EPPK1 PTPRH XPNPEP1 FKSG2 PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR PLA2G4A B4GALT3 HSPA2 ARL6IP1 HMG2L1 POLR2I DDX12 CYP2C19 NOMO2 LAP3 NIF3L1 NOL8 PFDN2 CDCA4 C16orf33 DUSP12 SCNM1 DIABLO PALB2 ALG6 GPATCH1 NARF BANP CHIA DDX47 A1CF ANKRD27 ACOT9 DOLPP1 TRMT5 TXNDC12 DNAJB11 TRIM6 C17orf37 PLCD4 C17orf49 ZNFX1 CDCA7L TMEM32 SCYL1BP1 NR2C2AP RHPN2 DLX3 ZNF490 RBP7 ZNF582 C6orf151 TRIM37 TBK1 ZNF673 MAD2L1 CKAP5 RBM14 COX17 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 GAS7 HPRT1 ARFGAP3 C15orf44 NCOA6 CP110 NAPB HNRPK RAD21 WARS PSAP RPN1 GOLGB1 COPB2 HAX1 MFN2 ANP32B DHX15 SHC1 NCBP2 RAE1 MBTPS1 VAPB GUSB PLOD2 TRRAP NDUFV2 GSTA4 CUL2 MTRR DMTF1 ADNP2 RBP1 ALDH5A1 PCNT POLR2D HMGB3 MTR STK3 TUBB2A CHD1 TEAD4 HIRIP3 SLC25A14 C1orf107 TTF1 CENPA RECQL DOPEY2 CA1 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 UCHL5IP DDX11 PDIA4 NCSTN PSMD11 UCP2 THOC5 MBD4 MAGOH IFT20 AR SLC25A17 YARS WEE1 SLC25A44 FTL EIF2C2 COL9A2 DHODH MDM1 PMS2L1 ZNF20 MYCL1 SNX6 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 DERL1 PARL S100PBP FANCL TOR3A MUS81 ABHD10 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 TMOD3 CHST6 RRAGD CCDC101 KIF18B TNS4 TRMT6 PARP9 TXNDC11 MRPL47 ERRFI1 CIRH1A TBC1D23 SIN3A INOC1 EEF2K ZBTB4 OMA1 TBC1D20 LCOR NOM1 TOR2A ZNF776 ZNF439
GO:0044424	CC	intracellular part	0.0195407374696401	0.124124977295966	9058	4.82944193113083	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 TMEM49 ILF2 NONO RNPS1 LASP1 SFRS2 PSMD2 SFRS10 AARS STOM RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR GDI1 PSRC1 M6PRBP1 ERCC3 CDK4 IRF1 ADM HCLS1 HAT1 PAFAH1B3 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN TPST2 CRYM ZNF415 SNRPG KRT32 IL15RA ALG3 ZNF304 SMPD4 NVL ECOP EPPK1 PTPRH XPNPEP1 FKSG2 PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR PLA2G4A B4GALT3 HSPA2 ARL6IP1 HMG2L1 POLR2I DDX12 CYP2C19 NOMO2 LAP3 NIF3L1 NOL8 PFDN2 CDCA4 C16orf33 DUSP12 SCNM1 DIABLO PALB2 ALG6 NARF BANP CHIA DDX47 A1CF ANKRD27 ACOT9 DOLPP1 TRMT5 TXNDC12 DNAJB11 C17orf37 PLCD4 C17orf49 ZNFX1 CDCA7L TMEM32 SCYL1BP1 NR2C2AP RHPN2 DLX3 ZNF490 RBP7 ZNF582 C6orf151 TRIM37 TBK1 MAD2L1 CKAP5 RBM14 COX17 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 GAS7 HPRT1 ARFGAP3 C15orf44 NCOA6 CP110 NAPB HNRPK RAD21 WARS PSAP RPN1 GOLGB1 COPB2 HAX1 MFN2 ANP32B DHX15 SHC1 NCBP2 RAE1 MBTPS1 VAPB GUSB PLOD2 TRRAP NDUFV2 GSTA4 CUL2 MTRR DMTF1 ADNP2 RBP1 ALDH5A1 PCNT POLR2D HMGB3 MTR STK3 TUBB2A CHD1 TEAD4 HIRIP3 SLC25A14 C1orf107 TTF1 CENPA RECQL DOPEY2 CA1 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 PDIA4 NCSTN PSMD11 UCP2 THOC5 MBD4 MAGOH IFT20 AR SLC25A17 YARS WEE1 SLC25A44 FTL EIF2C2 COL9A2 DHODH MDM1 PMS2L1 ZNF20 MYCL1 SNX6 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 DERL1 PARL S100PBP FANCL TOR3A MUS81 ABHD10 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 TMOD3 CHST6 RRAGD CCDC101 KIF18B TNS4 TRMT6 PARP9 TXNDC11 MRPL47 ERRFI1 CIRH1A SIN3A INOC1 EEF2K ZBTB4 OMA1 LCOR NOM1 TOR2A ZNF776 ZNF439
GO:0005634	CC	nucleus	0.0239206534422404	0.137333324003775	4285	5.53399717455909	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 ILF2 NONO RNPS1 SFRS2 SFRS10 RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR ERCC3 CDK4 IRF1 HCLS1 HAT1 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN ZNF415 SNRPG IL15RA ZNF304 NVL PARP1 HMGN2 CCND1 PSMA6 ATR HMG2L1 POLR2I DDX12 NOL8 CDCA4 C16orf33 DUSP12 SCNM1 PALB2 NARF BANP DDX47 A1CF TRMT5 DNAJB11 PLCD4 C17orf49 ZNFX1 CDCA7L NR2C2AP DLX3 ZNF490 ZNF582 C6orf151 MAD2L1 RBM14 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 NCOA6 HNRPK RAD21 HAX1 ANP32B DHX15 NCBP2 RAE1 TRRAP DMTF1 ADNP2 POLR2D HMGB3 STK3 CHD1 TEAD4 HIRIP3 C1orf107 TTF1 CENPA RECQL FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 THOC5 MBD4 MAGOH AR WEE1 MDM1 PMS2L1 ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 PARL S100PBP FANCL MUS81 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 RRAGD CCDC101 TRMT6 PARP9 CIRH1A SIN3A INOC1 ZBTB4 LCOR NOM1 ZNF776 ZNF439
GO:0043226	CC	organelle	0.0202315985624917	0.126086754568627	7513	4.70489561773787	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 TMEM49 ILF2 NONO RNPS1 LASP1 SFRS2 SFRS10 STOM RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR PSRC1 M6PRBP1 ERCC3 CDK4 IRF1 HCLS1 HAT1 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN TPST2 ZNF415 SNRPG KRT32 IL15RA ALG3 ZNF304 SMPD4 NVL ECOP EPPK1 PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR PLA2G4A B4GALT3 HSPA2 ARL6IP1 HMG2L1 POLR2I DDX12 CYP2C19 NOMO2 LAP3 NOL8 CDCA4 C16orf33 DUSP12 SCNM1 DIABLO PALB2 ALG6 NARF BANP DDX47 A1CF ANKRD27 ACOT9 DOLPP1 TRMT5 TXNDC12 DNAJB11 PLCD4 C17orf49 ZNFX1 CDCA7L TMEM32 NR2C2AP DLX3 ZNF490 ZNF582 C6orf151 TRIM37 MAD2L1 CKAP5 RBM14 COX17 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 ARFGAP3 NCOA6 CP110 NAPB HNRPK RAD21 PSAP RPN1 GOLGB1 COPB2 HAX1 MFN2 ANP32B DHX15 SHC1 NCBP2 RAE1 MBTPS1 VAPB GUSB PLOD2 TRRAP NDUFV2 MTRR DMTF1 ADNP2 ALDH5A1 PCNT POLR2D HMGB3 STK3 TUBB2A CHD1 TEAD4 HIRIP3 SLC25A14 C1orf107 TTF1 CENPA RECQL DOPEY2 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 PDIA4 NCSTN UCP2 THOC5 MBD4 MAGOH IFT20 AR SLC25A17 WEE1 SLC25A44 DHODH MDM1 PMS2L1 ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 DERL1 PARL S100PBP FANCL TOR3A MUS81 ABHD10 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 TMOD3 CHST6 RRAGD CCDC101 KIF18B TNS4 TRMT6 PARP9 TXNDC11 MRPL47 CIRH1A SIN3A INOC1 ZBTB4 OMA1 LCOR NOM1 TOR2A ZNF776 ZNF439
GO:0043227	CC	membrane-bound organelle	0.0216016859852476	0.130231627238087	6643	5.51457733858051	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 TMEM49 ILF2 NONO RNPS1 SFRS2 SFRS10 STOM RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR M6PRBP1 ERCC3 CDK4 IRF1 HCLS1 HAT1 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN TPST2 ZNF415 SNRPG IL15RA ALG3 ZNF304 SMPD4 NVL ECOP PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR B4GALT3 HSPA2 ARL6IP1 HMG2L1 POLR2I DDX12 CYP2C19 NOMO2 LAP3 NOL8 CDCA4 C16orf33 DUSP12 SCNM1 DIABLO PALB2 ALG6 NARF BANP DDX47 A1CF ANKRD27 ACOT9 DOLPP1 TRMT5 TXNDC12 DNAJB11 PLCD4 C17orf49 ZNFX1 CDCA7L TMEM32 NR2C2AP DLX3 ZNF490 ZNF582 C6orf151 TRIM37 MAD2L1 RBM14 COX17 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 ARFGAP3 NCOA6 NAPB HNRPK RAD21 PSAP RPN1 GOLGB1 COPB2 HAX1 MFN2 ANP32B DHX15 SHC1 NCBP2 RAE1 MBTPS1 VAPB GUSB PLOD2 TRRAP NDUFV2 MTRR DMTF1 ADNP2 ALDH5A1 POLR2D HMGB3 STK3 CHD1 TEAD4 HIRIP3 SLC25A14 C1orf107 TTF1 CENPA RECQL DOPEY2 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 PDIA4 NCSTN UCP2 THOC5 MBD4 MAGOH IFT20 AR SLC25A17 WEE1 SLC25A44 DHODH MDM1 PMS2L1 ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 DERL1 PARL S100PBP FANCL TOR3A MUS81 ABHD10 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 CHST6 RRAGD CCDC101 TRMT6 PARP9 TXNDC11 MRPL47 CIRH1A SIN3A INOC1 ZBTB4 OMA1 LCOR NOM1 TOR2A ZNF776 ZNF439
GO:0043229	CC	intracellular organelle	0.0202396804260985	0.126111290563409	7510	4.71170848550957	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 TMEM49 ILF2 NONO RNPS1 LASP1 SFRS2 SFRS10 STOM RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR PSRC1 M6PRBP1 ERCC3 CDK4 IRF1 HCLS1 HAT1 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN TPST2 ZNF415 SNRPG KRT32 IL15RA ALG3 ZNF304 SMPD4 NVL ECOP EPPK1 PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR PLA2G4A B4GALT3 HSPA2 ARL6IP1 HMG2L1 POLR2I DDX12 CYP2C19 NOMO2 LAP3 NOL8 CDCA4 C16orf33 DUSP12 SCNM1 DIABLO PALB2 ALG6 NARF BANP DDX47 A1CF ANKRD27 ACOT9 DOLPP1 TRMT5 TXNDC12 DNAJB11 PLCD4 C17orf49 ZNFX1 CDCA7L TMEM32 NR2C2AP DLX3 ZNF490 ZNF582 C6orf151 TRIM37 MAD2L1 CKAP5 RBM14 COX17 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 ARFGAP3 NCOA6 CP110 NAPB HNRPK RAD21 PSAP RPN1 GOLGB1 COPB2 HAX1 MFN2 ANP32B DHX15 SHC1 NCBP2 RAE1 MBTPS1 VAPB GUSB PLOD2 TRRAP NDUFV2 MTRR DMTF1 ADNP2 ALDH5A1 PCNT POLR2D HMGB3 STK3 TUBB2A CHD1 TEAD4 HIRIP3 SLC25A14 C1orf107 TTF1 CENPA RECQL DOPEY2 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 PDIA4 NCSTN UCP2 THOC5 MBD4 MAGOH IFT20 AR SLC25A17 WEE1 SLC25A44 DHODH MDM1 PMS2L1 ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 DERL1 PARL S100PBP FANCL TOR3A MUS81 ABHD10 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 TMOD3 CHST6 RRAGD CCDC101 KIF18B TNS4 TRMT6 PARP9 TXNDC11 MRPL47 CIRH1A SIN3A INOC1 ZBTB4 OMA1 LCOR NOM1 TOR2A ZNF776 ZNF439
GO:0043231	CC	intracellular membrane-bound organelle	0.0216081915374191	0.130250699252557	6641	5.51934209879773	POLE4 TAF2 CBX3 TARDBP DMRTA2 AHCTF1 TMEM49 ILF2 NONO RNPS1 SFRS2 SFRS10 STOM RBBP7 NUDC HDAC1 CACYBP DDX23 DKC1 MCM3 ADAR LBR M6PRBP1 ERCC3 CDK4 IRF1 HCLS1 HAT1 FAM50A PSMA4 NFIL3 ZNF263 PPRC1 PARN TPST2 ZNF415 SNRPG IL15RA ALG3 ZNF304 SMPD4 NVL ECOP PARP1 HMGN2 RPN2 CCND1 PSMA6 HARS2 TOR1B DCI ATR B4GALT3 HSPA2 ARL6IP1 HMG2L1 POLR2I DDX12 CYP2C19 NOMO2 LAP3 NOL8 CDCA4 C16orf33 DUSP12 SCNM1 DIABLO PALB2 ALG6 NARF BANP DDX47 A1CF ANKRD27 ACOT9 DOLPP1 TRMT5 TXNDC12 DNAJB11 PLCD4 C17orf49 ZNFX1 CDCA7L TMEM32 NR2C2AP DLX3 ZNF490 ZNF582 C6orf151 TRIM37 MAD2L1 RBM14 COX17 EXOSC10 ZNF254 PKN3 DNASE1L3 UPF2 SNRPB2 ARFGAP3 NCOA6 NAPB HNRPK RAD21 PSAP RPN1 GOLGB1 COPB2 HAX1 MFN2 ANP32B DHX15 SHC1 NCBP2 RAE1 MBTPS1 VAPB GUSB PLOD2 TRRAP NDUFV2 MTRR DMTF1 ADNP2 ALDH5A1 POLR2D HMGB3 STK3 CHD1 TEAD4 HIRIP3 SLC25A14 C1orf107 TTF1 CENPA RECQL DOPEY2 FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 PDIA4 NCSTN UCP2 THOC5 MBD4 MAGOH IFT20 AR SLC25A17 WEE1 SLC25A44 DHODH MDM1 PMS2L1 ZNF20 MYCL1 SUPT16H WBP11 USP39 BAZ1A TMEM48 TEX10 APPL1 DERL1 PARL S100PBP FANCL TOR3A MUS81 ABHD10 NXT1 UTP6 UPF3B SMC6 TXNL4B POLR3K CCDC59 RPP25 CHST6 RRAGD CCDC101 TRMT6 PARP9 TXNDC11 MRPL47 CIRH1A SIN3A INOC1 ZBTB4 OMA1 LCOR NOM1 TOR2A ZNF776 ZNF439
GO:0005886	CC	plasma membrane	0.00742390497401633	0.0767215389678584	2694	-4.25508884043167	ACVR1C CACNG6 HAS3 ENTPD3 SLC16A9 FAT SHC1 SDC4 VAPB GBP2 SLC25A14 OR2F1 NCSTN SLC25A17 TNS4 RGMA JTB STOM EFNA1 SLC7A7 PTPRN KCNS3 DSG1 SLC6A10P NUP85 TNFRSF12A KCNK6 LGR6
GO:0044428	CC	nuclear part	0.0336683417085427	0.162110423133415	995	5.18094061349929	TAF2 CBX3 AHCTF1 ILF2 RNPS1 SFRS2 HDAC1 DDX23 DKC1 MCM3 LBR ERCC3 HCLS1 SNRPG PARP1 POLR2I NOL8 C16orf33 NARF DDX47 A1CF C6orf151 RBM14 EXOSC10 SNRPB2 NCOA6 HNRPK RAD21 HAX1 DHX15 RAE1 TRRAP POLR2D SNRPA1 IFI16 DDX11 MAGOH BAZ1A TMEM48 TEX10 APPL1 NXT1 TXNL4B POLR3K CIRH1A NOM1
GO:0000307	CC	cyclin-dependent protein kinase holoenzyme complex	0.25	0.462910049886276	8	5.89964212421046	CDK4 CCND1
GO:0000428	CC	DNA-directed RNA polymerase complex	0.111111111111111	0.288675134594813	27	4.41315415213518	HCLS1 POLR2I POLR2D POLR3K
GO:0030880	CC	RNA polymerase complex	0.107142857142857	0.284056034415449	28	4.30713777406466	HCLS1 POLR2I POLR2D POLR3K
GO:0055029	CC	nuclear DNA-directed RNA polymerase complex	0.111111111111111	0.288675134594813	27	4.41315415213518	HCLS1 POLR2I POLR2D POLR3K
GO:0008250	CC	oligosaccharyl transferase complex	0.166666666666667	0.353553390593274	9	4.03097746121813	RPN2 RPN1
GO:0005689	CC	U12-dependent spliceosome	0.272727272727273	0.410099766132362	11	7.59002744633449	DDX23 C16orf33 C6orf151 DHX15
GO:0005637	CC	nuclear inner membrane	0.166666666666667	0.383482494423685	18	5.70228380647064	CBX3 LBR NARF
GO:0005665	CC	DNA-directed RNA polymerase II, core complex	0.147058823529412	0.342997170285018	17	4.82118309962993	HCLS1 POLR2I POLR2D
GO:0005721	CC	centric heterochromatin	0.25	0.5	4	4.17115015919865	CBX3
GO:0005639	CC	integral to nuclear inner membrane	0.25	0.5	4	4.17115015919865	LBR
GO:0031229	CC	intrinsic to nuclear inner membrane	0.25	0.5	4	4.17115015919865	LBR
GO:0005652	CC	nuclear lamina	0.25	0.5	4	4.17115015919865	NARF
GO:0030867	CC	rough endoplasmic reticulum membrane	0.2	0.349602949390050	10	5.18806130366186	ARL6IP1 RPN1 PLOD2
GO:0005684	CC	U2-dependent spliceosome	0.2	0.349602949390050	10	5.18806130366186	DDX23 SNRPB2 SNRPA1
GO:0030532	CC	small nuclear ribonucleoprotein complex	0.12	0.298607881119482	25	4.64235534935676	DDX23 SNRPG SNRPB2 SNRPA1
GO:0005682	CC	snRNP U5	0.25	0.5	4	4.17115015919865	DDX23
GO:0010369	CC	chromocenter	0.25	0.5	4	4.17115015919865	CBX3
GO:0003676	MF	nucleic acid binding	0.0244466468450611	0.140449363964005	3027	4.70358186122215	POLE4 TARDBP DMRTA2 AHCTF1 ABCF1 ILF2 NONO RNPS1 SFRS2 SFRS10 AARS HDAC1 DDX23 DKC1 MCM3 ADAR LBR ERCC3 IRF1 HCLS1 NFIL3 ZNF263 PPRC1 PARN ZNF415 SNRPG ZNF304 PARP1 HMGN2 PSMA6 ATR HMG2L1 POLR2I DDX12 NOL8 DUSP12 THUMPD2 EIF2C3 GPATCH1 BANP DDX47 A1CF TRMT5 C17orf49 ZNFX1 THAP8 DLX3 ZNF490 ZNF582 ZNF673 RBM14 EXOSC10 ZNF254 DNASE1L3 UPF2 SNRPB2 GAS7 HNRPK RPN1 DHX15 NCBP2 RAE1 DMTF1 ADNP2 HMGB3 RBMX2 CHD1 TEAD4 TTF1 CENPA RECQL FOXJ3 SNRPA1 SFRS6 IFI16 ZNF536 FOXN2 DDX11 MBD4 MAGOH AR YARS EIF2C2 PMS2L1 ZNF20 MYCL1 WBP11 MUS81 UPF3B POLR3K RPP25 TRMT6 TTC14 INOC1 EEF2K ZBTB4 LCOR ZNF776 ZNF439
GO:0003723	MF	RNA binding	0.0383458646616541	0.174729483046435	665	5.28657944160657	TARDBP ILF2 NONO RNPS1 SFRS2 SFRS10 AARS DDX23 DKC1 ADAR PPRC1 PARN SNRPG PSMA6 DDX12 NOL8 A1CF RBM14 EXOSC10 UPF2 SNRPB2 HNRPK RPN1 NCBP2 RAE1 RBMX2 SNRPA1 SFRS6 DDX11 MAGOH YARS UPF3B RPP25 TTC14
GO:0015643	MF	toxin binding	0.25	0.5	4	4.17115015919865	DSG1
GO:0003678	MF	DNA helicase activity	0.108108108108108	0.267060519960029	37	5.0049534727775	ERCC3 DDX12 CHD1 RECQL DDX11 INOC1
GO:0004003	MF	ATP-dependent DNA helicase activity	0.166666666666667	0.329140294302192	21	6.1597543470562	ERCC3 DDX12 CHD1 RECQL DDX11
GO:0008026	MF	ATP-dependent helicase activity	0.0638297872340425	0.222812454927731	94	4.15785143471018	DDX23 ERCC3 DDX12 DDX47 DHX15 CHD1 RECQL DDX11
GO:0008094	MF	DNA-dependent ATPase activity	0.088235294117647	0.258957184741825	51	4.61288208609813	MCM3 ERCC3 DDX12 CHD1 RECQL DDX11
GO:0005521	MF	lamin binding	0.4	0.547722557505166	5	7.65073684477158	LBR NARF
GO:0019841	MF	retinol binding	0.1875	0.372011904571422	8	4.32515202627457	RBP7 RBP1
GO:0016841	MF	ammonia-lyase activity	0.25	0.5	4	4.17115015919865	CRYM
GO:0004576	MF	oligosaccharyl transferase activity	0.166666666666667	0.353553390593274	9	4.03097746121813	RPN2 RPN1
GO:0004579	MF	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	0.1875	0.372011904571422	8	4.32515202627457	RPN2 RPN1
GO:0003720	MF	telomerase activity	0.25	0.5	4	4.17115015919865	DKC1
GO:0003945	MF	N-acetyllactosamine synthase activity	0.25	0.5	4	4.17115015919865	B4GALT3
GO:0016423	MF	tRNA (guanine) methyltransferase activity	0.25	0.5	4	4.17115015919865	TRMT5
GO:0008451	MF	X-Pro aminopeptidase activity	0.25	0.5	4	4.17115015919865	XPNPEP1
GO:0004767	MF	sphingomyelin phosphodiesterase activity	0.25	0.418330013267038	6	5.10891732848846	SMPD4 PSAP