GOname GO GO.term set.means set.sd n.genes z.score lead.genes GO:0006824 BP cobalt ion transport 0.25 0.5 4 4.93452030462688 TCN1 GO:0008236 MF serine-type peptidase activity 0.0628930817610063 0.236951487616095 159 6.7873477362995 TMPRSS11B KLK7 KLK13 PRSS3 DKFZP586H2123 TMPRSS11E KLK12 KLK5 PRSS27 DPP4 KLK10 GO:0006690 BP icosanoid metabolic process 0.097560975609756 0.278825935735943 41 5.72815084203457 HPGD PLA2G4A RNPEPL1 ALOX15B ALOX12 GO:0006691 BP leukotriene metabolic process 0.136363636363636 0.315542547950509 22 6.07343509072352 HPGD RNPEPL1 ALOX15B ALOX12 GO:0002221 BP pattern recognition receptor signaling pathway 0.25 0.5 4 4.93452030462688 NOD2 GO:0002224 BP toll-like receptor signaling pathway 0.25 0.5 4 4.93452030462688 NOD2 GO:0009395 BP phospholipid catabolic process 0.153846153846154 0.375533808099405 13 5.3182895389455 PLA2G4A PLA2G4F GO:0002218 BP activation of innate immune response 0.2 0.447213595499958 5 4.36289194490101 NOD2 GO:0008544 BP epidermis development 0.0666666666666667 0.241957470161487 120 6.3175279495497 SCEL SPINK5 KLK7 KRT32 LOR IVL KLK5 CST6 DLL1 GO:0002758 BP innate immune response-activating signal transduction 0.2 0.447213595499958 5 4.36289194490101 NOD2 GO:0046456 BP icosanoid biosynthetic process 0.103448275862069 0.279646152205514 29 5.14324080847307 HPGD RNPEPL1 ALOX15B ALOX12 GO:0004179 MF membrane alanyl aminopeptidase activity 0.136363636363636 0.323334895341432 11 4.29308877820713 RNPEPL1 TRHDE GO:0016116 BP carotenoid metabolic process 0.2 0.447213595499958 5 4.36289194490101 BCDO2 GO:0016101 BP diterpenoid metabolic process 0.181818181818182 0.404519917477945 11 5.8497605691486 BCDO2 RDH12 GO:0016108 BP tetraterpenoid metabolic process 0.2 0.447213595499958 5 4.36289194490101 BCDO2 GO:0004252 MF serine-type endopeptidase activity 0.0694444444444444 0.248147761580296 144 7.27137806948671 TMPRSS11B KLK7 KLK13 PRSS3 DKFZP586H2123 TMPRSS11E KLK12 KLK5 PRSS27 DPP4 KLK10 GO:0016284 MF alanine aminopeptidase activity 0.136363636363636 0.323334895341432 11 4.29308877820713 RNPEPL1 TRHDE GO:0018149 BP peptide cross-linking 0.111111111111111 0.323380833381777 18 4.38641998300621 LOR IVL GO:0016841 MF ammonia-lyase activity 0.25 0.5 4 4.93452030462688 CRYM GO:0031579 BP membrane raft organization and biogenesis 0.25 0.5 4 4.93452030462688 MAL GO:0016559 BP peroxisome fission 0.25 0.5 4 4.93452030462688 PEX11G GO:0042386 BP hemocyte differentiation 0.1875 0.372011904571422 8 5.15415056221629 MAL BLNK GO:0005497 MF androgen binding 0.375 0.478713553878169 4 7.51540321792865 SCGB2A1 AR GO:0031638 BP zymogen activation 0.25 0.5 4 4.93452030462688 PRSS3 GO:0004620 MF phospholipase activity 0.05625 0.224929665518757 80 4.18761934417751 PLA2G4A MGLL PLCD4 PLA2G4F SMPD2 GO:0004622 MF lysophospholipase activity 0.181818181818182 0.404519917477945 11 5.8497605691486 PLA2G4A MGLL GO:0048729 BP tissue morphogenesis 0.0648148148148148 0.238831595684354 54 4.08843652778317 SPINK5 LOR IVL DLL1 GO:0048730 BP epidermis morphogenesis 0.0897435897435897 0.277957656558344 39 5.08180009688763 SPINK5 LOR IVL DLL1 GO:0000271 BP polysaccharide biosynthetic process 0.0862068965517241 0.269555371903747 29 4.18397462815287 GYS2 B3GNT8 PPP1R3C GO:0007398 BP ectoderm development 0.0610687022900763 0.232237451125408 131 5.93893359131299 SCEL SPINK5 KLK7 KRT32 LOR IVL KLK5 CST6 DLL1 GO:0005149 MF interleukin-1 receptor binding 0.153846153846154 0.375533808099405 13 5.3182895389455 IL18 IL1F5 GO:0019369 BP arachidonic acid metabolic process 0.25 0.5 4 4.93452030462688 HPGD GO:0019370 BP leukotriene biosynthetic process 0.166666666666667 0.342997170285018 18 6.82076585474399 HPGD RNPEPL1 ALOX15B ALOX12 GO:0033692 BP cellular polysaccharide biosynthetic process 0.0862068965517241 0.269555371903747 29 4.18397462815287 GYS2 B3GNT8 PPP1R3C GO:0042253 BP granulocyte macrophage colony-stimulating factor biosynthetic process 0.2 0.447213595499958 5 4.36289194490101 IL18 GO:0004957 MF prostaglandin E receptor activity 0.2 0.447213595499958 5 4.36289194490101 HPGD GO:0004904 MF interferon receptor activity 0.2 0.447213595499958 5 4.36289194490101 IL22RA1 GO:0009913 BP epidermal cell differentiation 0.106060606060606 0.299936862042866 33 5.64224336504514 SPINK5 LOR IVL DLL1 GO:0042573 BP retinoic acid metabolic process 0.25 0.5 4 4.93452030462688 BCDO2 GO:0005576 CC extracellular region 0.0246478873239437 0.149308031515524 1704 6.14956550745415 RPTN A2ML1 GPX3 APOD SPOCK1 PROM1 ACPP TFF3 SPINK5 TCN1 KLK7 KLK13 MMP3 SCGB2A1 IL18 SPINK2 SCGB1D2 DEFB4 PRSS3 CRISP3 CRISP2 SOSTDC1 DKFZP586H2123 SLURP1 TMPRSS11E CHIA KLK12 IL1F5 KLK5 SPINK7 FAM3D LOC124220 PRSS27 SBSN IGFL1 SFTPG EREG QSOX1 DKK3 DPP4 CST6 PRRG4 BTC EDN3 KLK10 MUC5B COL9A2 DLL1 GO:0005501 MF retinoid binding 0.142857142857143 0.363136519601281 14 5.0946159494932 APOD RBP7 GO:0005626 CC insoluble fraction 0.15 0.366347548532523 20 6.42031269958036 MAL LOR GYS2 GO:0005615 CC extracellular space 0.031 0.169104087427742 500 4.68870161809855 A2ML1 GPX3 APOD SPOCK1 PROM1 MMP3 IL18 SCGB1D2 PRSS3 CRISP2 SLURP1 CHIA IL1F5 KLK5 EREG QSOX1 DKK3 GO:0042640 BP anagen 0.2 0.447213595499958 5 4.36289194490101 SPINK5 GO:0015355 MF secondary active monocarboxylate transmembrane transporter activity 0.2 0.447213595499958 5 4.36289194490101 SLC16A7 GO:0015379 MF potassium:chloride symporter activity 0.25 0.5 4 4.93452030462688 SLC12A6 GO:0019840 MF isoprenoid binding 0.142857142857143 0.363136519601281 14 5.0946159494932 APOD RBP7 GO:0007586 BP digestion 0.0632183908045977 0.238754005216002 87 5.04069262380403 TFF3 MMP3 SLC5A1 PRSS3 CHIA SLC15A1 GO:0007516 BP hemocyte development 0.214285714285714 0.393397896234722 7 5.55279575485283 MAL BLNK GO:0015293 MF symporter activity 0.0451388888888889 0.19534078563634 144 4.24707680852876 SLC16A9 SLC5A1 SLC16A7 SLC12A6 SLC37A2 SLC22A5 SLC16A6 SLC15A1 GO:0045176 BP apical protein localization 0.25 0.462910049886276 8 6.97933871998587 MAL SHROOM3 GO:0001523 BP retinoid metabolic process 0.181818181818182 0.404519917477945 11 5.8497605691486 BCDO2 RDH12 GO:0001533 CC cornified envelope 0.21875 0.406970514902493 16 8.5818205568293 SCEL LOR IVL CST6 GO:0017171 MF serine hydrolase activity 0.0625 0.236257507950315 160 6.75729090641121 TMPRSS11B KLK7 KLK13 PRSS3 DKFZP586H2123 TMPRSS11E KLK12 KLK5 PRSS27 DPP4 KLK10 GO:0017114 MF wide-spectrum protease inhibitor activity 0.2 0.447213595499958 5 4.36289194490101 A2ML1 GO:0019961 MF interferon binding 0.2 0.447213595499958 5 4.36289194490101 IL22RA1 GO:0015889 BP cobalamin transport 0.25 0.5 4 4.93452030462688 TCN1 GO:0030057 CC desmosome 0.166666666666667 0.353553390593274 9 4.8216515982853 DSG1 PKP3 GO:0015643 MF toxin binding 0.25 0.5 4 4.93452030462688 DSG1 GO:0008035 MF high-density lipoprotein binding 0.25 0.5 4 4.93452030462688 APOD GO:0043450 BP alkene biosynthetic process 0.166666666666667 0.342997170285018 18 6.82076585474399 HPGD RNPEPL1 ALOX15B ALOX12 GO:0032604 BP granulocyte macrophage colony-stimulating factor production 0.2 0.447213595499958 5 4.36289194490101 IL18 GO:0043449 BP alkene metabolic process 0.136363636363636 0.315542547950509 22 6.07343509072352 HPGD RNPEPL1 ALOX15B ALOX12 GO:0030431 BP sleep 0.2 0.447213595499958 5 4.36289194490101 IL18 GO:0030141 CC secretory granule 0.090909090909091 0.291937104060571 33 4.74287918755053 TFF3 SPINK5 CRISP3 GO:0051289 BP protein homotetramerization 0.166666666666667 0.353553390593274 9 4.8216515982853 GPX3 ALDH5A1 GO:0006775 BP fat-soluble vitamin metabolic process 0.117647058823529 0.332105582077536 17 4.54101642267232 BCDO2 RDH12 GO:0006776 BP vitamin A metabolic process 0.142857142857143 0.363136519601281 14 5.0946159494932 BCDO2 RDH12 GO:0006720 BP isoprenoid metabolic process 0.0925925925925926 0.278631167738513 27 4.37966187331993 BCDO2 RDH12 MVK GO:0006721 BP terpenoid metabolic process 0.142857142857143 0.363136519601281 14 5.0946159494932 BCDO2 RDH12 GO:0008195 MF phosphatidate phosphatase activity 0.2 0.447213595499958 5 4.36289194490101 LPPR4 GO:0030216 BP keratinocyte differentiation 0.134615384615385 0.333397429734913 26 6.51125594627052 SCEL LOR IVL EREG GO:0008105 BP asymmetric protein localization 0.2 0.421637021355784 10 6.1710261023834 MAL SHROOM3