GOname	GO	GO.term	set.means	set.sd	n.genes	z.score	lead.genes
GO:0008283	BP	cell proliferation	0.0521262002743484	0.211350980122796	729	5.84122963231878	CDKN3 CSE1L PCNA INSIG1 CDC25B CKS1B BUB1B DLG7 CDC6 CKS2 PIM2 CDC7 TTK CHEK1 LAMP3 BLM GINS1 CDKN2A CENPF MDK CXCR4 TPX2 MKI67 CKLF TIPIN KIF15 HELLS RACGAP1 TCF19 TNFSF13B UHRF1 RECQL4 KLF11 OSMR POLA1 TRAF5 E2F1 TIMELESS CDKN2C BRCA1 ISG20 PAX6 KIF2C RIPK2 CDCA7
GO:0030705	BP	cytoskeleton-dependent intracellular transport	0.0905172413793103	0.276618855113851	116	5.24645844333408	KIF11 CENPE MPHOSPH1 KIF14 KIFC1 KIF4A KIF20A KIF15 KIF18A KIF22 KIF23 KIF2C
GO:0008278	CC	cohesin complex	0.4	0.547722557505166	5	6.02522743032993	CDCA5 SGOL2
GO:0030894	CC	replisome	0.214285714285714	0.377964473009227	14	5.12341974083905	RPA2 PRIM1 POLA1 RPA3
GO:0043596	CC	nuclear replication fork	0.21875	0.363719214046587	16	5.60501989418163	RPA2 PRIM1 POLA1 MCM7 RPA3
GO:0043566	MF	structure-specific DNA binding	0.0869565217391304	0.263208182888407	92	4.42431971685738	RPA2 RAD51AP1 HLF FEN1 BLM MCM4 PMS2L11 MCM6 RAD51 RPA3
GO:0030554	MF	adenyl nucleotide binding	0.0462154294032023	0.199809304996946	1374	6.5587221347726	RPS6KA5 TK1 TOP2A RUVBL1 SMC4 MCM5 MCM2 STCH ACTL6A LIG1 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 PIM2 KIF11 CDC7 RAD54L TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 POLQ KIFC1 ATP2C1 TPX2 CHEK2 MKI67 MCM4 DNA2 GMPS KIF4A KIF20A ATAD2 DDX60 KIF15 DDX25 HELLS KIF18A CHTF18 SLFN11 MASTL KIAA1804 HSPA6 ACVR1C FIGNL1 RECQL4 SLFN13 FANCM PIF1 PKN3 PMS2L11 RRM1 ARAF MCM6 KIF22 NEK2 KIF23 RAD51 FASTKD2 MCM7 KIF2C AURKB RIPK2 MYO5C MCM8
GO:0043623	BP	cellular protein complex assembly	0.098360655737705	0.286060485025276	61	4.23601099831873	ANLN CSE1L CENPE CENPF MIS12 NUP205 TMEM48
GO:0016363	CC	nuclear matrix	0.108695652173913	0.296517630696742	46	4.17776651661059	RUVBL1 BLM CENPF KIF4A POLA1 GMCL1
GO:0051656	BP	establishment of organelle localization	0.260869565217391	0.448977758544880	23	8.16436378190892	BIRC5 NUSAP1 DLG7 CENPE CENPF CDCA5
GO:0043601	CC	nuclear replisome	0.214285714285714	0.377964473009227	14	5.12341974083905	RPA2 PRIM1 POLA1 RPA3
GO:0004386	MF	helicase activity	0.0928571428571429	0.278651133615421	140	5.96652774996714	RUVBL1 HLTF RAD54L BLM POLQ MCM4 DNA2 DDX60 DDX25 HELLS CHTF18 RECQL4 FANCM PIF1 MCM6
GO:0031497	BP	chromatin assembly	0.0897435897435897	0.276146838216693	78	4.24811558691196	MCM2 NEFH CHAF1B HIST1H1C ASF1B HELLS H2AFV CENPA
GO:0051640	BP	organelle localization	0.1875	0.396557769456266	32	6.66774102055444	BIRC5 NUSAP1 DLG7 CENPE CENPF CDCA5
GO:0048015	BP	phosphoinositide-mediated signaling	0.105	0.303972021572693	100	5.9056489414855	PCNA TOP2A SPAG5 BUB1B RFC4 ZWINT AURKA NDC80 CKS2 FEN1 P2RY1
GO:0000082	BP	G1/S transition of mitotic cell cycle	0.176470588235294	0.366852974867781	34	6.41389497661491	CDKN3 DBF4 CDC7 CDKN2A CDCA5 CDKN2C CCNE1
GO:0000085	BP	G2 phase of mitotic cell cycle	0.5	0.5	5	7.6213677099404	BLM CENPF KPNA2
GO:0000086	BP	G2/M transition of mitotic cell cycle	0.235294117647059	0.437237316097603	17	6.26480204910206	BIRC5 CHEK1 CDKN2A CCNB1
GO:0000087	BP	M phase of mitotic cell cycle	0.228365384615385	0.404698517422187	208	21.3279670574102	ANLN BIRC5 MPHOSPH9 NUSAP1 RUVBL1 SMC4 CDC25B CDC20 SPAG5 CDC2 PTTG1 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 SMC2 KIF11 CENPE MPHOSPH1 KNTC1 CENPF KIFC1 SPC25 TPX2 NCAPD3 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 HELLS CDCA8 MIS12 NUF2 CDCA5 KIF22 STAG1 TIMELESS CCNA2 NEK2 KIF23 KIAA1009 KIF2C AURKB CDCA3 FAM33A
GO:0000070	BP	mitotic sister chromatid segregation	0.448275862068966	0.506120178878476	29	16.3786998891886	NUSAP1 SMC4 DLG7 ZWINT NDC80 SMC2 CENPE KIFC1 NCAPD3 NCAPH NCAPG NCAPG2 CDCA5
GO:0000075	BP	cell cycle checkpoint	0.318965517241379	0.455938167765286	58	16.1427237151891	BIRC5 FANCG BUB1B CDC6 ZWINT CDC45L RAD1 TTK CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 CHEK2 ZWILCH TIPIN CCNA2 BRCA1 CCNE2
GO:0000076	BP	DNA replication checkpoint	0.666666666666667	0.516397779494322	6	11.2632824391716	CDC6 CDC45L CDT1 TIPIN
GO:0000077	BP	DNA damage checkpoint	0.211538461538462	0.40430377003132	26	6.88460856290497	RAD1 CHEK1 BLM CHEK2 TIPIN CCNA2
GO:0000079	BP	regulation of cyclin-dependent protein kinase activity	0.186274509803922	0.373641329535766	51	8.36006425648782	CDKN3 CKS1B CDC6 CKS2 CHEK1 BLM CDKN2A HERC5 CCNA2 CDKN2C CCNE2
GO:0006996	BP	organelle organization and biogenesis	0.0596669750231267	0.229535521561132	1081	9.02899067444357	ANLN TAF5 RPS6KA5 NUSAP1 TOP2A RUVBL1 SMC4 MCM2 ACTL6A HLTF SPAG5 EZH2 PTTG1 BUB1B DLG7 ZWINT AURKA NDC80 CKS2 SMC2 PIM2 NEFH KIF11 BID CHAF1B TTK CENPE EXOSC9 MPHOSPH1 BLM KIF14 CDKN2A CENPF PTTG3 HIST1H1C KIFC1 ATP2C1 NCAPD3 NCAPH EXOSC8 PRC1 ASF1B KIF4A SUV39H1 NCAPG KIF20A KIF15 NCAPG2 STAG3 HELLS KIF18A MIS12 RACGAP1 NOP5/NOP58 CDCA5 CENPH SASS6 RECQL4 SUV39H2 PIF1 STMN1 KPNA2 KIF22 H2AFV BRCA1 KIF23 CENPA TIMM8A SYCP2 KIF2C TMEM48 BXDC2
GO:0008637	BP	apoptotic mitochondrial changes	0.1875	0.403112887414928	16	4.71244320768573	PIM2 BID CDKN2A
GO:0006950	BP	response to stress	0.0518108651911469	0.210695248778086	994	6.80750426835686	RPS6KA5 PCNA AKR1B1 TOP2A CD14 LIG1 C1QB MDC1 PTTG1 FANCG CD163 RFC4 RAD51AP1 RAD1 RAD54L EXO1 PARP2 NUDT1 FEN1 CHAF1B CCR1 BARD1 CHEK1 LY75 BLM POLE2 SELE PLA2G7 MICB LY96 POLQ MDK CXCR4 CHEK2 FANCI DTL TIPIN DCLRE1B FANCE C1QC UHRF1 GEN1 HSPA6 RECQL4 FANCM POLA1 TOPBP1 PMS2L11 PLSCR1 PLOD2 TIMELESS CCNA2 FANCA BRCA1 RAD51 IL1RAP P2RY1 MCM7 RPA3 RIPK2 MTPN
GO:0006974	BP	response to DNA damage stimulus	0.112956810631229	0.30088463148156	301	11.3059797692895	PCNA TOP2A LIG1 MDC1 PTTG1 FANCG RFC4 RAD51AP1 RAD1 RAD54L EXO1 PARP2 NUDT1 FEN1 CHAF1B BARD1 CHEK1 BLM POLE2 POLQ CHEK2 FANCI DTL TIPIN DCLRE1B FANCE UHRF1 GEN1 RECQL4 FANCM POLA1 TOPBP1 PMS2L11 TIMELESS CCNA2 FANCA BRCA1 RAD51 MCM7 RPA3
GO:0031224	CC	intrinsic to membrane	0.0129482071713147	0.105202851672879	4518	-5.41690050601723	PIGX ALG10 ACVR1C OSMR KPNA2 TMEM106C LPCAT1 KPNA1 PLSCR1 MMD TMEFF1 NCF4 CELSR3 IL1RAP CD38 SLC25A40 CYP4F3 P2RY1 NUP205 TMEM194 FPRL2 TMEM48 GOLT1B FLRT3 SLAMF8 FA2H NUP62CL AADACL1 TMEM68 TRIM59 DPY19L2 HS6ST2 KIAA1524 CLEC2B SLC16A1 TMEM22 CSE1L INSIG1 CD14 TMPO CD163 SELL CCR1 CA9 KIAA0133 LAMP3 LY75 SYNGR3 ADAMDEC1 SELE NUP155 GPR19 CXCR4 ATP2C1 TMEM97 NUP210 PAQR4 LPPR4 SLC38A6 FAM69A NUP107 NETO2 CKLF C3orf52 SLC15A3 TMEM180 FICD SLC25A19 TNFSF13B ZIC2 ZDHHC23 C1orf162 ALG10B TMEM71
GO:0016796	MF	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.315789473684211	0.447540386625407	19	9.12916031184846	RAD1 EXO1 FEN1 EXOSC9 EXOSC8 ISG20 XRN2
GO:0016728	MF	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	0.375	0.478713553878169	4	5.03206204176873	RRM2 RRM1
GO:0004748	MF	ribonucleoside-diphosphate reductase activity	0.375	0.478713553878169	4	5.03206204176873	RRM2 RRM1
GO:0016891	MF	endoribonuclease activity, producing 5'-phosphomonoesters	0.173913043478261	0.357029908734864	23	5.18586946857181	RNASEH2A EXO1 FEN1 RPP25 DBR1
GO:0016893	MF	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.142857142857143	0.329341173353118	28	4.5488738310459	RNASEH2A EXO1 FEN1 RPP25 DBR1
GO:0016895	MF	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.4375	0.495515604482557	8	8.37927893470831	RAD1 EXO1 FEN1 ISG20
GO:0016896	MF	exoribonuclease activity, producing 5'-phosphomonoesters	0.25	0.398862017608733	12	5.6263793484574	EXOSC9 EXOSC8 ISG20 XRN2
GO:0033261	BP	regulation of S phase	0.25	0.427425207132555	14	6.07756463026859	CDC7 CDT1 TIPIN TIMELESS
GO:0007093	BP	mitotic cell cycle checkpoint	0.25	0.430516930661509	30	8.90110172318369	BUB1B ZWINT TTK BLM KNTC1 CENPF ZWILCH CCNA2
GO:0007094	BP	mitotic cell cycle spindle assembly checkpoint	0.333333333333333	0.516397779494322	6	5.43481989678624	TTK CENPF
GO:0007096	BP	regulation of exit from mitosis	0.25	0.452267016866645	12	5.6263793484574	ANLN BIRC5 KNTC1
GO:0007098	BP	centrosome cycle	0.192307692307692	0.383973823894152	13	4.37110660701412	KIF11 SASS6 BRCA1
GO:0009719	BP	response to endogenous stimulus	0.0876288659793814	0.269081212857610	388	9.26737707022352	PCNA TOP2A LIG1 MDC1 PTTG1 FANCG RFC4 RAD51AP1 RAD1 RAD54L EXO1 PARP2 NUDT1 FEN1 CHAF1B BARD1 CHEK1 BLM POLE2 POLQ CHEK2 FANCI DTL TIPIN DCLRE1B FANCE UHRF1 GEN1 RECQL4 FANCM POLA1 TOPBP1 PMS2L11 TIMELESS CCNA2 FANCA BRCA1 RAD51 MCM7 RPA3
GO:0007067	BP	mitosis	0.225728155339806	0.40275660371688	206	20.9519326610229	ANLN BIRC5 NUSAP1 RUVBL1 SMC4 CDC25B CDC20 SPAG5 CDC2 PTTG1 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 SMC2 KIF11 CENPE MPHOSPH1 KNTC1 CENPF KIFC1 SPC25 TPX2 NCAPD3 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 HELLS CDCA8 MIS12 NUF2 CDCA5 KIF22 STAG1 TIMELESS CCNA2 NEK2 KIF23 KIAA1009 KIF2C AURKB CDCA3 FAM33A
GO:0007051	BP	spindle organization and biogenesis	0.526315789473684	0.485159888035959	19	15.6824520114767	SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK PRC1 STMN1 KIF23
GO:0007052	BP	mitotic spindle organization and biogenesis	0.363636363636364	0.452267016866645	11	8.07747846090143	KIF11 TTK PRC1 STMN1 KIF23
GO:0007059	BP	chromosome segregation	0.375	0.475011150627371	60	19.5233160665331	NUSAP1 TOP2A SMC4 PTTG1 DLG7 ZWINT NDC80 SMC2 CENPE CENPF KIFC1 NCAPD3 NCAPH NCAPG DSN1 NCAPG2 STAG3 MIS12 NUF2 CDCA5 SGOL2 RECQL4 STAG1 BRCA1
GO:0033205	BP	cytokinesis during cell cycle	0.4	0.547722557505166	5	6.02522743032993	NUSAP1 RACGAP1
GO:0007088	BP	regulation of mitosis	0.1625	0.364928865565711	40	6.32675108935688	ANLN BIRC5 NUSAP1 DLG7 MPHOSPH1 KNTC1 NEK2
GO:0007089	BP	traversing start control point of mitotic cell cycle	0.4	0.547722557505166	5	6.02522743032993	CDC2 CDC6
GO:0031570	BP	DNA integrity checkpoint	0.293103448275862	0.453503059119276	29	10.4093666908677	CDC6 CDC45L RAD1 CHEK1 BLM CDT1 CHEK2 TIPIN CCNA2
GO:0031572	BP	G2/M transition DNA damage checkpoint	0.3	0.447213595499958	5	4.42908715071947	BLM CCNA2
GO:0007076	BP	mitotic chromosome condensation	0.5	0.516397779494322	16	13.6382100726447	NUSAP1 SMC4 SMC2 NCAPD3 NCAPH NCAPG NCAPG2 CDCA5
GO:0031576	BP	G2/M transition checkpoint	0.3	0.447213595499958	5	4.42908715071947	BLM CCNA2
GO:0031577	BP	spindle checkpoint	0.428571428571429	0.534522483824849	7	7.66921889817795	BIRC5 TTK CENPF
GO:0007010	BP	cytoskeleton organization and biogenesis	0.0526315789473684	0.216338003855214	475	4.7561134996142	ANLN NUSAP1 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK CENPE MPHOSPH1 KIF14 KIFC1 ATP2C1 PRC1 KIF4A KIF20A KIF15 KIF18A RACGAP1 SASS6 STMN1 KPNA2 KIF22 BRCA1 KIF23 KIF2C
GO:0042393	MF	histone binding	0.214285714285714	0.42581531362632	14	5.12341974083905	DEK CHAF1B ASF1B
GO:0007017	BP	microtubule-based process	0.110552763819095	0.302078984888075	199	8.9195811181587	NUSAP1 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK CENPE MPHOSPH1 KIF14 KIFC1 PRC1 KIF4A KIF20A KIF15 KIF18A SASS6 STMN1 KPNA2 KIF22 BRCA1 KIF23 KIF2C
GO:0007018	BP	microtubule-based movement	0.109375	0.300903245509075	96	6.092461842206	KIF11 CENPE MPHOSPH1 KIF14 KIFC1 KIF4A KIF20A KIF15 KIF18A KIF22 KIF23 KIF2C
GO:0031519	CC	PcG protein complex	0.357142857142857	0.475594865605671	7	6.32014975641873	EZH2 PCGF6 EED
GO:0007049	BP	cell cycle	0.134776536312849	0.325477732248988	716	21.9362244905589	ANLN CDKN3 BIRC5 MPHOSPH9 NUSAP1 RUVBL1 SMC4 CDC25B CKS1B MCM2 LIG1 CDC20 MDC1 SPAG5 CDC2 PTTG1 FANCG BUB1B DLG7 CDC6 ZWINT AURKA CDC45L NDC80 CKS2 SMC2 DBF4 PIM2 KIF11 RAD1 CDC7 RAD54L EXO1 CHAF1B MLF1 TTK CENPE MPHOSPH1 BARD1 CHEK1 BLM KNTC1 CDKN2A CENPF KIFC1 CDT1 SPC25 TPX2 CHEK2 MKI67 NCAPD3 NCAPH FANCI SENP5 CCNB1 PRC1 ZWILCH GMNN CEP55 SUV39H1 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 STAG3 HERC5 E2F8 HELLS CDCA8 MIS12 RACGAP1 NUF2 MND1 CDCA5 UHRF1 CABLES2 C11orf82 SGOL2 SASS6 RECQL4 CKAP2 SUV39H2 POLA1 CASP8AP2 STMN1 KPNA2 MCM6 KIF22 STAG1 E2F1 TIMELESS CCNA2 CDKN2C BRCA1 NEK2 KIF23 RAD51 CCNE2 PSMC3IP KIAA1009 SYCP2 MCM7 KIF2C AURKB CCNE1 RBM7 CDCA3 MCM8 FAM33A E2F7
GO:0004523	MF	ribonuclease H activity	0.5	0.547722557505166	6	8.34905116797895	RNASEH2A EXO1 FEN1
GO:0004527	MF	exonuclease activity	0.16	0.34166459266004	50	6.94937711659764	RAD1 EXO1 FEN1 EXOSC9 EXOSC8 ISG20L1 ISG20 LOC81691 XRN2 THEX1
GO:0004529	MF	exodeoxyribonuclease activity	0.4375	0.495515604482557	8	8.37927893470831	RAD1 EXO1 FEN1 ISG20
GO:0004518	MF	nuclease activity	0.0864661654135338	0.257547275709405	133	5.28593604638264	RNASEH2A RAD1 EXO1 FEN1 EXOSC9 EXOSC8 ISG20L1 GEN1 FANCM ISG20 LOC81691 RPP25 DBR1 XRN2 THEX1
GO:0004540	MF	ribonuclease activity	0.132075471698113	0.312418349274999	53	5.70216970930875	RNASEH2A EXO1 FEN1 EXOSC9 EXOSC8 ISG20 RPP25 DBR1 XRN2
GO:0000444	CC	MIS12/MIND type complex	0.5	0.577350269189626	4	6.81654531211942	DSN1 MIS12
GO:0004532	MF	exoribonuclease activity	0.25	0.398862017608733	12	5.6263793484574	EXOSC9 EXOSC8 ISG20 XRN2
GO:0016538	MF	cyclin-dependent protein kinase regulator activity	0.583333333333333	0.491596040125088	6	9.8061668035753	CKS1B CKS2 CABLES2 CCNE2
GO:0000175	MF	3'-5'-exoribonuclease activity	0.277777777777778	0.440958551844098	9	5.46705090209315	EXOSC9 EXOSC8 ISG20
GO:0016605	CC	PML body	0.175	0.335410196624968	20	4.87010900149756	BLM CHEK2 TOPBP1 ISG20 RAD51
GO:0000278	BP	mitotic cell cycle	0.196369636963696	0.379813506871709	303	21.8064815780498	ANLN CDKN3 BIRC5 MPHOSPH9 NUSAP1 RUVBL1 SMC4 CDC25B CDC20 SPAG5 CDC2 PTTG1 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 SMC2 DBF4 KIF11 CDC7 TTK CENPE MPHOSPH1 CHEK1 BLM KNTC1 CDKN2A CENPF KIFC1 CDT1 SPC25 TPX2 NCAPD3 NCAPH CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 HELLS CDCA8 MIS12 NUF2 CDCA5 POLA1 STMN1 KPNA2 KIF22 STAG1 E2F1 TIMELESS CCNA2 CDKN2C NEK2 KIF23 KIAA1009 KIF2C AURKB CCNE1 CDCA3 FAM33A
GO:0000279	BP	M phase	0.215613382899628	0.393484357404106	269	22.7961809510439	ANLN BIRC5 MPHOSPH9 NUSAP1 RUVBL1 SMC4 CDC25B CDC20 SPAG5 CDC2 PTTG1 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 CKS2 SMC2 PIM2 KIF11 RAD1 RAD54L EXO1 CENPE MPHOSPH1 CHEK1 KNTC1 CENPF KIFC1 SPC25 TPX2 NCAPD3 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 STAG3 HELLS CDCA8 MIS12 NUF2 MND1 CDCA5 KPNA2 KIF22 STAG1 TIMELESS CCNA2 NEK2 KIF23 RAD51 PSMC3IP KIAA1009 SYCP2 KIF2C AURKB RBM7 CDCA3 FAM33A
GO:0000226	BP	microtubule cytoskeleton organization and biogenesis	0.146067415730337	0.338800081764265	89	8.34227578401553	NUSAP1 SPAG5 BUB1B ZWINT AURKA NDC80 CKS2 KIF11 TTK PRC1 SASS6 STMN1 BRCA1 KIF23 KIF2C
GO:0000228	CC	nuclear chromosome	0.161290322580645	0.339126838546761	93	9.57956404780646	RPA2 MCM2 SMC2 PRIM1 CHEK1 BLM NCAPD3 SUV39H1 ORC6L TIPIN STAG3 PIF1 POLA1 TOPBP1 TIMELESS RAD51 SYCP2 MCM7 RPA3
GO:0000793	CC	condensed chromosome	0.254716981132075	0.423159379746726	53	12.0850172365831	SMC4 BUB1B SMC2 CENPE CHEK1 BLM CENPF NCAPD3 SUV39H1 DSN1 STAG3 MIS12 TOPBP1 RAD51 SYCP2
GO:0000794	CC	condensed nuclear chromosome	0.209677419354839	0.382408889985294	31	7.4446525807821	CHEK1 BLM NCAPD3 SUV39H1 STAG3 TOPBP1 RAD51 SYCP2
GO:0000795	CC	synaptonemal complex	0.192307692307692	0.383973823894152	13	4.37110660701412	BLM STAG3 SYCP2
GO:0000796	CC	condensin complex	0.75	0.5	4	10.3855118528208	SMC4 SMC2 NCAPD3
GO:0007346	BP	regulation of mitotic cell cycle	0.225	0.416044733579195	60	11.2152235319065	BIRC5 CDC2 BUB1B CDC6 ZWINT TTK BLM KNTC1 CDKN2A CENPF CDT1 ZWILCH FBXO5 CCNA2
GO:0000785	CC	chromatin	0.0980392156862745	0.281319865763271	153	6.69963535675688	DNMT1 MYBL2 MCM2 TMPO NEFH CENPF HIST1H1C HMG4L ASF1B SUV39H1 TIPIN HELLS SUV39H2 POLA1 H2AFV TIMELESS CENPA MCM7
GO:0000775	CC	chromosome, pericentric region	0.337837837837838	0.446509354303124	74	19.4043838014946	BIRC5 BUB1B ZWINT NDC80 CENPE ITGB3BP CENPF SPC25 APITD1 ZWILCH SUV39H1 CENPM DSN1 CENPN HELLS CDCA8 MIS12 CENPK NUF2 SGOL2 CENPH SUV39H2 KIF22 CENPA KIF2C AURKB MLF1IP CENPQ CENPO
GO:0000776	CC	kinetochore	0.274193548387097	0.444197960325111	31	10.0108417331301	BUB1B ZWINT CENPE CENPF ZWILCH DSN1 MIS12 CENPH KIF22
GO:0000777	CC	condensed chromosome kinetochore	0.625	0.517549169506766	8	12.1652132550862	BUB1B CENPE CENPF DSN1 MIS12
GO:0000779	CC	condensed chromosome, pericentric region	0.555555555555556	0.52704627669473	9	11.4162588623090	BUB1B CENPE CENPF DSN1 MIS12
GO:0000724	BP	double-strand break repair via homologous recombination	0.307692307692308	0.434859246311452	13	7.3415024885679	RAD51AP1 RAD54L BLM BRCA1 RAD51
GO:0000725	BP	recombinational repair	0.307692307692308	0.434859246311452	13	7.3415024885679	RAD51AP1 RAD54L BLM BRCA1 RAD51
GO:0044453	CC	nuclear membrane part	0.0806451612903226	0.247710413200281	93	4.0127783552244	CSE1L TMPO NUP155 NUP210 NUP107 KPNA2 KPNA1 NUP205 TMEM48 NUP62CL
GO:0044454	CC	nuclear chromosome part	0.171875	0.3475395375475	64	8.5451571816314	RPA2 MCM2 PRIM1 BLM NCAPD3 ORC6L TIPIN STAG3 PIF1 POLA1 TIMELESS SYCP2 MCM7 RPA3
GO:0044459	CC	plasma membrane part	0.00901687027341478	0.0890064107734224	1719	-4.2271717248587	ACVR1C OSMR MMD NCF4 IL1RAP P2RY1 FLRT3 CLEC2B MDC1 CD163 SELL CCR1 LY75 SYNGR3 MICB GPR19 CXCR4 TNFSF13B ZIC2
GO:0044422	CC	organelle part	0.0406365883807169	0.186405259449730	3236	8.23895709196125	ANLN TAF5 FILIP1L BIRC5 CEP78 MPHOSPH9 NUSAP1 CSE1L PCNA TOP2A RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 RPA2 CDC25B MCM2 ACTL6A CDC20 SPAG5 CDC2 EZH2 TMPO BUB1B DLG7 CDC6 RFC4 ZWINT TOE1 AURKA NDC80 SMC2 NEFH KIF11 BID WDHD1 CHAF1B TTK CENPE PRIM1 EXOSC9 ITGB3BP MPHOSPH1 BARD1 CHEK1 LAMP3 BLM KNTC1 KIF14 ABAT NUP155 TAF1A KRT31 CDKN2A CENPF POLQ HIST1H1C KIFC1 CDT1 SPC25 ATP2C1 TPX2 RPL39L CHEK2 MKI67 NUP210 NCAPD3 APITD1 CCNB1 HMG4L PRC1 ASF1B ZWILCH KIF4A SUV39H1 CENPM KIF20A NUP107 FBXO5 ORC6L TIPIN KIF15 C3orf52 DSN1 CENPN SLC15A3 STAG3 E2F8 HELLS KIF18A CDCA8 MIS12 RACGAP1 CENPK NOP5/NOP58 SLC25A19 NUF2 PCGF6 CDCA5 SGOL2 CENPH KRT80 SASS6 PIGX ALG10 CKAP2 SUV39H2 CYP4B1 PIF1 POLA1 CEP72 TOPBP1 RPL30 STMN1 KPNA2 TMEM106C LPCAT1 KPNA1 KIF22 H2AFV PLOD2 E2F1 TIMELESS MMD BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 TIMM8A SLC25A40 KIAA1009 CYP4F3 SYCP2 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 DMN TMEM48 GOLT1B GMCL1 KTELC1 MLF1IP MYO5C CENPQ FA2H CENPO NUP62CL XRN2 FAM33A NOM1 E2F7
GO:0044424	CC	intracellular part	0.0282623095606094	0.156478318447095	9058	5.9313375225101	ANLN TAF5 KIAA1524 RPS6KA5 TK1 FILIP1L BIRC5 CEP78 MPHOSPH9 TMEM22 IFI44 NUSAP1 STAT1 DEK CSE1L PCNA AKR1B1 TOP2A ENO2 IFI30 RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MTHFD2 CDC25B RRM2 MCM2 STCH FOXM1 ACTL6A LIG1 CDC20 C1QB HLTF RNASEH2A MDC1 SPAG5 CDC2 MTF2 EZH2 TMPO LSP1 PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 GCH1 SMC2 DBF4 S100P NEFH APOC1 KIF11 RAD1 BID CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 TTK MELK CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 ISG15 LAMP3 RASGRP1 CYP27B1 BLM POLE2 GINS1 ISL1 NTS KNTC1 KIF14 ABAT NUP155 TAF1A KRT31 ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PRSS16 PTTG3 CXCR4 HIST1H1C IFI35 KIFC1 CDT1 SPC25 ATP2C1 NCF2 TPX2 RPL39L IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 GMPS HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B ZWILCH KIF4A DTL SUV39H1 NCAPG HJURP CENPM KIF20A NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN KIF15 C3orf52 DCLRE1B DSN1 CENPN NCAPG2 SLC15A3 STAG3 HERC5 DDX25 GIPC2 E2F8 HELLS FANCE MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 PRTFDC1 CENPK NOP5/NOP58 SLC25A19 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 C1QC PHF19 UHRF1 SLFN11 C6orf173 HYLS1 C11orf82 GEN1 SGOL2 EID3 CENPH KRT80 SASS6 ZNF280C PIGX ALG10 RECQL4 KLF11 CKAP2 FANCM SUV39H2 AGBL3 PSIP1 ZNF26 CYP4B1 PIF1 HMMR GINS2 POLA1 CEP72 PKN3 TOPBP1 NEDD4 TACC3 TRAF5 CASP8AP2 RPL30 STMN1 KPNA2 RRM1 TMEM106C LPCAT1 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 PLOD2 E2F1 TIMELESS MMD CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 NCF4 TIMM8A PAX6 SLC25A40 PSMC3IP KIAA1009 LHX2 FOXD1 CYP4F3 SYCP2 PTP4A3 SP4 POU2F3 ZNF200 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 RIPK2 EED ANXA9 NUP205 SULF1 DMN ZNF473 CCNE1 TMEM48 GOLT1B COQ4 S100PBP GMCL1 KTELC1 ABHD10 MLF1IP MYO5C RPP25 DBR1 BXDC2 HSPBAP1 CENPQ FA2H CENPO ATG3 NUP62CL CDCA3 COL8A2 XRN2 PARP9 MCM8 CDCA7 MTPN FAM33A NOM1 E2F7 IRX2 ZNF367
GO:0044425	CC	membrane part	0.0122878876535986	0.102377000111064	5127	-6.33937627776499	PIGX ALG10 ACVR1C OSMR CYP4B1 KPNA2 TMEM106C LPCAT1 KPNA1 PLSCR1 PLOD2 MMD TMEFF1 NCF4 CELSR3 IL1RAP CD38 SLC25A40 CYP4F3 CYP7B1 P2RY1 NUP205 TMEM194 FPRL2 TMEM48 GOLT1B FLRT3 SLAMF8 FA2H NUP62CL AADACL1 TMEM68 TRIM59 DPY19L2 HS6ST2 KIAA1524 CLEC2B SLC16A1 MPHOSPH9 TMEM22 CSE1L INSIG1 CD14 MDC1 TMPO CD163 SELL CCR1 CA9 KIAA0133 LAMP3 LY75 SYNGR3 ADAMDEC1 SELE MICB NUP155 GPR19 CXCR4 ATP2C1 TMEM97 NUP210 PAQR4 LPPR4 SLC38A6 FAM69A NUP107 NETO2 CKLF C3orf52 SLC15A3 TMEM180 FICD SLC25A19 TNFSF13B ZIC2 ZDHHC23 C1orf162 ALG10B TMEM71
GO:0044427	CC	chromosomal part	0.179078014184397	0.366315502364984	282	18.9322355554668	BIRC5 PCNA SMC4 DNMT1 MYBL2 RPA2 MCM2 TMPO BUB1B RFC4 ZWINT NDC80 SMC2 NEFH CENPE PRIM1 ITGB3BP CHEK1 BLM CENPF HIST1H1C CDT1 SPC25 NCAPD3 APITD1 HMG4L ASF1B ZWILCH SUV39H1 CENPM ORC6L TIPIN DSN1 CENPN STAG3 HELLS CDCA8 MIS12 CENPK NUF2 CDCA5 SGOL2 CENPH SUV39H2 PIF1 POLA1 KIF22 H2AFV TIMELESS CENPA SYCP2 MCM7 KIF2C AURKB RPA3 MLF1IP CENPQ CENPO
GO:0044428	CC	nuclear part	0.050251256281407	0.205525868154874	995	6.44858176677166	TAF5 CSE1L PCNA TOP2A RUVBL1 RPA2 MCM2 ACTL6A EZH2 TMPO BUB1B TOE1 SMC2 WDHD1 CHAF1B PRIM1 EXOSC9 MPHOSPH1 BARD1 CHEK1 BLM NUP155 TAF1A CDKN2A CENPF POLQ CHEK2 MKI67 NUP210 NCAPD3 KIF4A SUV39H1 NUP107 ORC6L TIPIN STAG3 E2F8 NOP5/NOP58 PCGF6 PIF1 POLA1 TOPBP1 KPNA2 KPNA1 E2F1 TIMELESS BRCA1 ISG20 RAD51 SYCP2 LOC81691 MCM7 RPA3 EED NUP205 TMEM48 GMCL1 NUP62CL XRN2 NOM1 E2F7
GO:0044446	CC	intracellular organelle part	0.0407625542467452	0.186680279777608	3226	8.28014616924868	ANLN TAF5 FILIP1L BIRC5 CEP78 MPHOSPH9 NUSAP1 CSE1L PCNA TOP2A RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 RPA2 CDC25B MCM2 ACTL6A CDC20 SPAG5 CDC2 EZH2 TMPO BUB1B DLG7 CDC6 RFC4 ZWINT TOE1 AURKA NDC80 SMC2 NEFH KIF11 BID WDHD1 CHAF1B TTK CENPE PRIM1 EXOSC9 ITGB3BP MPHOSPH1 BARD1 CHEK1 LAMP3 BLM KNTC1 KIF14 ABAT NUP155 TAF1A KRT31 CDKN2A CENPF POLQ HIST1H1C KIFC1 CDT1 SPC25 ATP2C1 TPX2 RPL39L CHEK2 MKI67 NUP210 NCAPD3 APITD1 CCNB1 HMG4L PRC1 ASF1B ZWILCH KIF4A SUV39H1 CENPM KIF20A NUP107 FBXO5 ORC6L TIPIN KIF15 C3orf52 DSN1 CENPN SLC15A3 STAG3 E2F8 HELLS KIF18A CDCA8 MIS12 RACGAP1 CENPK NOP5/NOP58 SLC25A19 NUF2 PCGF6 CDCA5 SGOL2 CENPH KRT80 SASS6 PIGX ALG10 CKAP2 SUV39H2 CYP4B1 PIF1 POLA1 CEP72 TOPBP1 RPL30 STMN1 KPNA2 TMEM106C LPCAT1 KPNA1 KIF22 H2AFV PLOD2 E2F1 TIMELESS MMD BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 TIMM8A SLC25A40 KIAA1009 CYP4F3 SYCP2 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 DMN TMEM48 GOLT1B GMCL1 KTELC1 MLF1IP MYO5C CENPQ FA2H CENPO NUP62CL XRN2 FAM33A NOM1 E2F7
GO:0044430	CC	cytoskeletal part	0.067699836867863	0.240643394025701	613	8.14238146948011	ANLN FILIP1L BIRC5 CEP78 NUSAP1 TOP2A CDC25B CDC20 SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA NEFH KIF11 TTK CENPE MPHOSPH1 KNTC1 KIF14 KRT31 CENPF KIFC1 TPX2 CCNB1 PRC1 KIF4A KIF20A FBXO5 KIF15 KIF18A RACGAP1 KRT80 SASS6 CKAP2 CEP72 STMN1 KIF22 BRCA1 NEK2 KIF23 KIAA1009 KIF2C AURKB DMN MYO5C FAM33A
GO:0042770	BP	DNA damage response, signal transduction	0.133333333333333	0.326830509313592	45	5.31321154838678	RAD1 CHEK1 BLM CHEK2 TIPIN CCNA2 BRCA1
GO:0000819	BP	sister chromatid segregation	0.433333333333333	0.504006932993731	30	16.0745500278122	NUSAP1 SMC4 DLG7 ZWINT NDC80 SMC2 CENPE KIFC1 NCAPD3 NCAPH NCAPG NCAPG2 CDCA5
GO:0005730	CC	nucleolus	0.0674846625766871	0.239052511299030	163	4.1188780646584	TAF5 TOP2A EXOSC9 MPHOSPH1 BLM TAF1A CDKN2A MKI67 NOP5/NOP58 POLA1 LOC81691 XRN2 NOM1
GO:0000808	CC	origin recognition complex	0.333333333333333	0.516397779494322	6	5.43481989678624	MCM2 ORC6L
GO:0007126	BP	meiosis	0.152173913043478	0.335457850272524	69	7.70356760418458	CKS2 PIM2 RAD1 RAD54L EXO1 CHEK1 STAG3 MND1 NEK2 RAD51 PSMC3IP SYCP2 RBM7
GO:0007127	BP	meiosis I	0.172413793103448	0.360452643733382	29	5.76655198106262	CKS2 RAD1 CHEK1 STAG3 RAD51 SYCP2
GO:0007130	BP	synaptonemal complex assembly	0.3	0.447213595499958	5	4.42908715071947	STAG3 SYCP2
GO:0005856	CC	cytoskeleton	0.0425851703406814	0.19378541902424	998	4.67389096868808	ANLN FILIP1L BIRC5 CEP78 NUSAP1 TOP2A CDC25B CDC20 SPAG5 CDC2 LSP1 BUB1B DLG7 CDC6 AURKA NEFH KIF11 TTK CENPE MPHOSPH1 KNTC1 KIF14 KRT31 CENPF KIFC1 TPX2 CCNB1 PRC1 KIF4A KIF20A FBXO5 KIF15 KIF18A RACGAP1 KRT80 SASS6 CKAP2 CEP72 STMN1 KIF22 BRCA1 NEK2 KIF23 KIAA1009 KIF2C AURKB DMN MYO5C FAM33A
GO:0005886	CC	plasma membrane	0.0113214550853749	0.0999530071906409	2694	-4.54626659850198	ACVR1C OSMR PLSCR1 MMD TMEFF1 NCF4 CELSR3 IL1RAP CD38 PTP4A3 P2RY1 FPRL2 FLRT3 CLEC2B SLC16A1 ENO2 CD14 ACTL6A RGS1 MDC1 LSP1 CD163 SELL CCR1 CA9 RASGRP1 LY75 SYNGR3 SELE MICB LY96 GPR19 CXCR4 TNFSF13B ZIC2 ALG10B GBP5
GO:0003008	BP	system process	0.00384985563041386	0.0579399112152942	1039	-4.44008282325161	TIMM8A PAX6 GCH1 NTS ABAT
GO:0005871	CC	kinesin complex	0.176470588235294	0.350944104817110	17	4.53289468503334	KIF11 KIF15 KIF23 KIF2C
GO:0005874	CC	microtubule	0.084862385321101	0.268808995209991	218	6.6154832745598	BIRC5 NUSAP1 SPAG5 CDC2 KIF11 CENPE MPHOSPH1 KNTC1 KIF14 KIFC1 PRC1 KIF4A KIF20A KIF15 KIF18A RACGAP1 CKAP2 STMN1 KIF22 KIF23 KIF2C
GO:0005875	CC	microtubule associated complex	0.0897435897435897	0.275551051463907	117	5.20924517186143	KIF11 CENPE MPHOSPH1 KIF14 KIFC1 KIF4A KIF20A KIF15 KIF18A KIF22 KIF23 KIF2C
GO:0005876	CC	spindle microtubule	0.388888888888889	0.50163132570455	18	11.1000836197501	BIRC5 SPAG5 CDC2 KIF11 KNTC1 PRC1 KIF4A
GO:0005813	CC	centrosome	0.0954198473282443	0.284973033925303	131	5.98012607220378	BIRC5 CEP78 TOP2A CDC25B DLG7 AURKA MPHOSPH1 KIFC1 CCNB1 KIF15 SASS6 CEP72 NEK2 KIAA1009
GO:0005814	CC	centriole	0.285714285714286	0.487950036474267	7	4.97108061465951	BIRC5 TOP2A
GO:0005815	CC	microtubule organizing center	0.0928571428571429	0.278651133615421	140	5.96652774996714	BIRC5 CEP78 TOP2A CDC25B DLG7 AURKA MPHOSPH1 KIFC1 CCNB1 KIF15 SASS6 CEP72 BRCA1 NEK2 KIAA1009
GO:0005819	CC	spindle	0.301369863013699	0.446745375740829	73	17.04335151108	BIRC5 CDC20 SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA KIF11 TTK CENPE KNTC1 KIF14 CENPF KIFC1 TPX2 PRC1 KIF4A FBXO5 RACGAP1 KIF23 KIAA1009 AURKB FAM33A
GO:0019238	MF	cyclohydrolase activity	0.4	0.547722557505166	5	6.02522743032993	MTHFD2 GCH1
GO:0005524	MF	ATP binding	0.0495319812792512	0.206462187355896	1282	7.19917580759394	RPS6KA5 TK1 TOP2A RUVBL1 SMC4 MCM5 MCM2 STCH ACTL6A LIG1 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 PIM2 KIF11 CDC7 RAD54L TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 POLQ KIFC1 ATP2C1 TPX2 CHEK2 MKI67 MCM4 DNA2 GMPS KIF4A KIF20A ATAD2 DDX60 KIF15 DDX25 HELLS KIF18A CHTF18 SLFN11 MASTL KIAA1804 HSPA6 ACVR1C FIGNL1 RECQL4 SLFN13 FANCM PIF1 PKN3 PMS2L11 RRM1 ARAF MCM6 KIF22 NEK2 KIF23 RAD51 FASTKD2 MCM7 KIF2C AURKB RIPK2 MYO5C MCM8
GO:0005694	CC	chromosome	0.158284023668639	0.347871035543507	338	18.0062670280011	BIRC5 PCNA TOP2A SMC4 DNMT1 MYBL2 RPA2 MCM2 TMPO BUB1B RFC4 ZWINT NDC80 SMC2 NEFH CENPE PRIM1 ITGB3BP CHEK1 BLM CENPF HIST1H1C CDT1 SPC25 NCAPD3 FANCI APITD1 HMG4L ASF1B ZWILCH SUV39H1 CENPM ORC6L TIPIN DSN1 CENPN STAG3 HELLS CDCA8 MIS12 CENPK NUF2 CDCA5 SGOL2 CENPH SUV39H2 PIF1 POLA1 TOPBP1 KIF22 H2AFV TIMELESS CENPA RAD51 SYCP2 MCM7 KIF2C AURKB RPA3 MLF1IP CENPQ CENPO
GO:0005663	CC	DNA replication factor C complex	0.333333333333333	0.516397779494322	6	5.43481989678624	PCNA RFC4
GO:0005664	CC	nuclear origin of replication recognition complex	0.333333333333333	0.516397779494322	6	5.43481989678624	MCM2 ORC6L
GO:0017056	MF	structural constituent of nuclear pore	0.4	0.418330013267038	5	6.02522743032993	NUP155 TMEM48 NUP62CL
GO:0005657	CC	replication fork	0.316666666666667	0.444958993332112	30	11.5096283794122	PCNA DNMT1 RPA2 RFC4 PRIM1 CHEK1 BLM CDT1 POLA1 MCM7 RPA3
GO:0017076	MF	purine nucleotide binding	0.0383933845245127	0.182743134467428	1693	4.93193123108401	RPS6KA5 TK1 TOP2A RUVBL1 SMC4 MCM5 MCM2 STCH ACTL6A LIG1 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 PIM2 KIF11 CDC7 RAD54L TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 POLQ KIFC1 ATP2C1 TPX2 CHEK2 MKI67 MCM4 DNA2 GMPS KIF4A KIF20A ATAD2 DDX60 KIF15 DDX25 HELLS KIF18A CHTF18 SLFN11 MASTL KIAA1804 GBP5 HSPA6 ACVR1C FIGNL1 RECQL4 SLFN13 FANCM PIF1 PKN3 PMS2L11 RRM1 ARAF MCM6 KIF22 NEK2 KIF23 RAD51 FASTKD2 MCM7 KIF2C AURKB RIPK2 MYO5C MCM8 DOCK11
GO:0005622	CC	intracellular	0.0279388508170796	0.155252547462572	9485	5.91306141583581	ANLN TAF5 KIAA1524 RPS6KA5 TK1 FILIP1L BIRC5 CEP78 MPHOSPH9 ARHGAP11B TMEM22 IFI44 NUSAP1 STAT1 DEK CSE1L PCNA AKR1B1 TOP2A ENO2 IFI30 RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MTHFD2 CDC25B RRM2 MCM2 STCH FOXM1 ACTL6A LIG1 CDC20 C1QB HLTF RNASEH2A MDC1 SPAG5 CDC2 MTF2 EZH2 TMPO LSP1 PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 GCH1 SMC2 DBF4 S100P NEFH APOC1 KIF11 RAD1 BID CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 TTK MELK CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 ISG15 LAMP3 RASGRP1 CYP27B1 BLM POLE2 GINS1 ISL1 NTS KNTC1 KIF14 ABAT NUP155 TAF1A KRT31 ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PRSS16 PTTG3 CXCR4 HIST1H1C IFI35 KIFC1 CDT1 SPC25 ATP2C1 NCF2 TPX2 RPL39L IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 GMPS HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B TBC1D15 ZWILCH KIF4A DTL SUV39H1 NCAPG HJURP CENPM KIF20A NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN KIF15 ISG20L1 C3orf52 DCLRE1B DSN1 CENPN NCAPG2 SLC15A3 STAG3 HERC5 DDX25 GIPC2 E2F8 HELLS FANCE DEPDC1 MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 PRTFDC1 CENPK NOP5/NOP58 SLC25A19 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 C1QC PHF19 UHRF1 SLFN11 C6orf173 HYLS1 PLEKHG4 C11orf82 GEN1 SGOL2 EID3 CENPH KRT80 SASS6 ZNF280C PIGX ALG10 RECQL4 KLF11 SLFN13 TRIM74 CKAP2 FANCM SUV39H2 AGBL3 PSIP1 ZNF26 CYP4B1 PIF1 WDR67 HMMR GINS2 POLA1 CEP72 SYDE2 PKN3 TOPBP1 TRIM52 NEDD4 TACC3 TRAF5 CASP8AP2 RPL30 STMN1 KPNA2 RRM1 TMEM106C LPCAT1 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 PLOD2 E2F1 TIMELESS MMD CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 NCF4 TIMM8A PAX6 SLC25A40 PSMC3IP KIAA1009 LHX2 FOXD1 CYP4F3 SYCP2 PTP4A3 SP4 POU2F3 ZNF200 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 RIPK2 EED ANXA9 NUP205 SULF1 DMN ZNF473 CCNE1 TMEM48 GOLT1B COQ4 S100PBP GMCL1 KTELC1 ABHD10 MLF1IP MYO5C RPP25 DBR1 BXDC2 HSPBAP1 CENPQ FA2H CENPO ATG3 NUP62CL CDCA3 COL8A2 XRN2 PARP9 MCM8 CDCA7 MTPN FAM33A THEX1 NOM1 TRIM59 E2F7 IRX2 ZNF367 RTKN2
GO:0005643	CC	nuclear pore	0.0984848484848485	0.266309492734949	66	4.41410667632156	CSE1L NUP155 NUP210 NUP107 KPNA2 KPNA1 NUP205 TMEM48 NUP62CL
GO:0005634	CC	nucleus	0.0432905484247375	0.193389591005427	4285	11.3456257089805	ANLN TAF5 RPS6KA5 BIRC5 NUSAP1 STAT1 DEK CSE1L PCNA TOP2A RUVBL1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MCM2 FOXM1 ACTL6A LIG1 HLTF RNASEH2A MDC1 CDC2 MTF2 EZH2 TMPO PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH RAD1 CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 NUP155 TAF1A ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PTTG3 HIST1H1C IFI35 KIFC1 CDT1 SPC25 TPX2 IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B KIF4A DTL SUV39H1 NCAPG HJURP CENPM NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN DCLRE1B DSN1 CENPN NCAPG2 STAG3 DDX25 E2F8 HELLS FANCE MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 CENPK NOP5/NOP58 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 PHF19 UHRF1 SLFN11 C6orf173 C11orf82 GEN1 SGOL2 EID3 CENPH ZNF280C RECQL4 KLF11 FANCM SUV39H2 PSIP1 ZNF26 PIF1 GINS2 POLA1 PKN3 TOPBP1 CASP8AP2 KPNA2 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 E2F1 TIMELESS CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 PAX6 PSMC3IP KIAA1009 LHX2 FOXD1 SYCP2 SP4 POU2F3 ZNF200 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 ZNF473 CCNE1 TMEM48 S100PBP GMCL1 MLF1IP RPP25 DBR1 BXDC2 CENPQ CENPO NUP62CL XRN2 PARP9 MCM8 CDCA7 NOM1 E2F7 IRX2 ZNF367
GO:0010458	BP	exit from mitosis	0.230769230769231	0.438529009653515	13	5.36123856753205	ANLN BIRC5 KNTC1
GO:0050000	BP	chromosome localization	0.833333333333333	0.408248290463863	6	14.1775137103644	BIRC5 DLG7 CENPE CENPF CDCA5
GO:0000922	CC	spindle pole	0.227272727272727	0.428932027228889	22	6.85920362922313	DLG7 KIF11 KNTC1 CENPF TPX2
GO:0000910	BP	cytokinesis	0.177419354838710	0.377456114375658	31	6.16155800460811	ANLN BIRC5 NUSAP1 PRC1 RACGAP1 AURKB
GO:0032392	BP	DNA geometric change	0.214285714285714	0.377964473009227	14	5.12341974083905	MCM2 MCM4 MCM6 RAD51
GO:0003774	MF	motor activity	0.0774647887323944	0.254712845186784	142	4.69443892435427	KIF11 CENPE MPHOSPH1 KIF14 KIFC1 KIF4A KIF20A KIF15 KIF18A KIF22 KIF23 KIF2C MYO5C
GO:0003777	MF	microtubule motor activity	0.13125	0.325535099898341	80	6.95874474817202	KIF11 CENPE MPHOSPH1 KIF14 KIFC1 KIF4A KIF20A KIF15 KIF18A KIF22 KIF23 KIF2C
GO:0032297	BP	negative regulation of DNA replication initiation	0.666666666666667	0.516397779494322	6	11.2632824391716	CDC6 CDC45L CDT1 TIPIN
GO:0051052	BP	regulation of DNA metabolic process	0.166666666666667	0.345032779671177	57	7.7813990687578	PCNA CDC6 CDC45L BLM CDT1 GMNN TIPIN PIF1 KPNA2 KPNA1 BRCA1 RAD51
GO:0051053	BP	negative regulation of DNA metabolic process	0.272727272727273	0.455842305838552	22	8.38187351518005	CDC6 CDC45L BLM CDT1 GMNN TIPIN
GO:0003697	MF	single-stranded DNA binding	0.117021276595745	0.298779509320233	47	4.63103044667779	RPA2 RAD51AP1 BLM MCM4 MCM6 RAD51 RPA3
GO:0003682	MF	chromatin binding	0.0944444444444444	0.279389829188863	90	4.88411419195888	TOP2A ACTL6A CDC6 CHAF1B CENPF SUV39H1 CDCA5 SUV39H2 POLA1 CENPA
GO:0003677	MF	DNA binding	0.0362044486512068	0.176750390679059	2113	4.82172398754536	TAF5 NUSAP1 STAT1 DEK PCNA TOP2A DNMT1 MYBL2 MCM5 RPA2 MCM2 FOXM1 LIG1 HLTF MTF2 EZH2 TMPO PTTG1 FANCG RFC4 RAD51AP1 NEFH RAD1 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 MLF1 BLM POLE2 ISL1 TAF1A ZNF165 HOXC6 CDKN2A HOXD10 POLQ HIST1H1C CDT1 IRX5 MCM4 APITD1 DNA2 HOXD11 HMG4L KIF4A HJURP ORC6L KIF15 E2F8 HELLS MXD3 TCF19 ZIC2 MND1 PCGF6 UHRF1 GEN1 ZNF280C KLF11 FANCM PSIP1 PIF1 POLA1 TOPBP1 C16orf75 PMS2L11 MCM6 KIF22 H2AFV E2F1 TEAD4 BRCA1 CENPA RAD51 PAX6 PSMC3IP LHX2 FOXD1 SYCP2 SP4 POU2F3 MCM7 KIF2C RPA3 ZNF473 MCM8 E2F7 IRX2 ZNF367
GO:0003678	MF	DNA helicase activity	0.121621621621622	0.298268275155042	37	4.30759574176449	RUVBL1 BLM MCM4 RECQL4 PIF1 MCM6
GO:0015630	CC	microtubule cytoskeleton	0.0944148936170213	0.279991767862775	376	10.0698093725598	BIRC5 CEP78 NUSAP1 TOP2A CDC25B CDC20 SPAG5 CDC2 BUB1B DLG7 CDC6 AURKA KIF11 TTK CENPE MPHOSPH1 KNTC1 KIF14 CENPF KIFC1 TPX2 CCNB1 PRC1 KIF4A KIF20A FBXO5 KIF15 KIF18A RACGAP1 SASS6 CKAP2 CEP72 STMN1 KIF22 BRCA1 NEK2 KIF23 KIAA1009 KIF2C AURKB FAM33A
GO:0008094	MF	DNA-dependent ATPase activity	0.166666666666667	0.341565025531987	51	7.35908123064071	TOP2A MCM5 MCM2 RFC4 BLM MCM4 PIF1 MCM6 RAD51 MCM7 MCM8
GO:0032553	MF	ribonucleotide binding	0.0401978973407545	0.186796761533327	1617	5.35344023918276	RPS6KA5 TK1 TOP2A RUVBL1 SMC4 MCM5 MCM2 STCH ACTL6A LIG1 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 PIM2 KIF11 CDC7 RAD54L TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 POLQ KIFC1 ATP2C1 TPX2 CHEK2 MKI67 MCM4 DNA2 GMPS KIF4A KIF20A ATAD2 DDX60 KIF15 DDX25 HELLS KIF18A CHTF18 SLFN11 MASTL KIAA1804 GBP5 HSPA6 ACVR1C FIGNL1 RECQL4 SLFN13 FANCM PIF1 PKN3 PMS2L11 RRM1 ARAF MCM6 KIF22 NEK2 KIF23 RAD51 FASTKD2 MCM7 KIF2C AURKB RIPK2 MYO5C MCM8 DOCK11
GO:0032555	MF	purine ribonucleotide binding	0.0401978973407545	0.186796761533327	1617	5.35344023918276	RPS6KA5 TK1 TOP2A RUVBL1 SMC4 MCM5 MCM2 STCH ACTL6A LIG1 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 PIM2 KIF11 CDC7 RAD54L TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 POLQ KIFC1 ATP2C1 TPX2 CHEK2 MKI67 MCM4 DNA2 GMPS KIF4A KIF20A ATAD2 DDX60 KIF15 DDX25 HELLS KIF18A CHTF18 SLFN11 MASTL KIAA1804 GBP5 HSPA6 ACVR1C FIGNL1 RECQL4 SLFN13 FANCM PIF1 PKN3 PMS2L11 RRM1 ARAF MCM6 KIF22 NEK2 KIF23 RAD51 FASTKD2 MCM7 KIF2C AURKB RIPK2 MYO5C MCM8 DOCK11
GO:0032559	MF	adenyl ribonucleotide binding	0.0488461538461538	0.205108486720291	1300	7.06985301118936	RPS6KA5 TK1 TOP2A RUVBL1 SMC4 MCM5 MCM2 STCH ACTL6A LIG1 HLTF CDC2 BUB1B VRK1 CDC6 RFC4 TRIP13 AURKA SMC2 PIM2 KIF11 CDC7 RAD54L TTK MELK PLK4 CENPE MPHOSPH1 CHEK1 BLM KIF14 POLQ KIFC1 ATP2C1 TPX2 CHEK2 MKI67 MCM4 DNA2 GMPS KIF4A KIF20A ATAD2 DDX60 KIF15 DDX25 HELLS KIF18A CHTF18 SLFN11 MASTL KIAA1804 HSPA6 ACVR1C FIGNL1 RECQL4 SLFN13 FANCM PIF1 PKN3 PMS2L11 RRM1 ARAF MCM6 KIF22 NEK2 KIF23 RAD51 FASTKD2 MCM7 KIF2C AURKB RIPK2 MYO5C MCM8
GO:0032508	BP	DNA duplex unwinding	0.214285714285714	0.377964473009227	14	5.12341974083905	MCM2 MCM4 MCM6 RAD51
GO:0006323	BP	DNA packaging	0.150943396226415	0.353012958893085	106	9.46856671135234	NUSAP1 TOP2A SMC4 MCM2 SMC2 NEFH CHAF1B HIST1H1C NCAPD3 NCAPH ASF1B NCAPG NCAPG2 HELLS CDCA5 H2AFV CENPA
GO:0006310	BP	DNA recombination	0.114583333333333	0.294503745545538	96	6.45777059772724	RUVBL1 LIG1 RAD51AP1 RAD54L EXO1 CHEK1 BLM MND1 RECQL4 KPNA2 KPNA1 BRCA1 RAD51 PSMC3IP
GO:0006302	BP	double-strand break repair	0.157142857142857	0.338061701891407	35	5.69076220893907	RAD51AP1 RAD54L FEN1 BLM POLA1 BRCA1 RAD51
GO:0051383	BP	kinetochore organization and biogenesis	1	0	4	13.9544783935222	CENPE CENPF MIS12 CENPH
GO:0051320	BP	S phase	0.2	0.376968517462526	20	5.66855382800388	CDC7 CDT1 TIPIN POLA1 TIMELESS
GO:0051321	BP	meiotic cell cycle	0.147887323943662	0.331601807219605	71	7.55654673183511	CKS2 PIM2 RAD1 RAD54L EXO1 CHEK1 STAG3 MND1 NEK2 RAD51 PSMC3IP SYCP2 RBM7
GO:0051325	BP	interphase	0.193181818181818	0.374716890693986	88	11.4581051642143	CDKN3 BIRC5 CDC2 CDC6 DBF4 CDC7 CHEK1 BLM CDKN2A CENPF CDT1 CCNB1 TIPIN CDCA5 POLA1 KPNA2 E2F1 TIMELESS CDKN2C CCNE1
GO:0051327	BP	M phase of meiotic cell cycle	0.152173913043478	0.335457850272524	69	7.70356760418458	CKS2 PIM2 RAD1 RAD54L EXO1 CHEK1 STAG3 MND1 NEK2 RAD51 PSMC3IP SYCP2 RBM7
GO:0051329	BP	interphase of mitotic cell cycle	0.186746987951807	0.372130020661330	83	10.7065892933457	CDKN3 BIRC5 CDC2 CDC6 DBF4 CDC7 CHEK1 BLM CDKN2A CENPF CDT1 CCNB1 CDCA5 POLA1 KPNA2 E2F1 CDKN2C CCNE1
GO:0051310	BP	metaphase plate congression	0.75	0.5	4	10.3855118528208	CENPE CENPF CDCA5
GO:0051319	BP	G2 phase	0.5	0.5	5	7.6213677099404	BLM CENPF KPNA2
GO:0051301	BP	cell division	0.236607142857143	0.409855171995586	224	23.0308996967366	ANLN BIRC5 NUSAP1 RUVBL1 SMC4 CDC25B CKS1B LIG1 CDC20 SPAG5 CDC2 PTTG1 BUB1B CDC6 ZWINT NDC80 CKS2 SMC2 KIF11 CDC7 CENPE MPHOSPH1 BLM KNTC1 CENPF KIFC1 SPC25 NCAPD3 NCAPH SENP5 CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN DSN1 NCAPG2 HELLS CDCA8 MIS12 RACGAP1 NUF2 CDCA5 CABLES2 SGOL2 STAG1 TIMELESS CCNA2 NEK2 KIF23 CCNE2 KIAA1009 SYCP2 AURKB CCNE1 CDCA3 FAM33A
GO:0051303	BP	establishment of chromosome localization	0.833333333333333	0.408248290463863	6	14.1775137103644	BIRC5 DLG7 CENPE CENPF CDCA5
GO:0030496	CC	midbody	0.25	0.424918292799399	10	5.1358367421264	BIRC5 CDC2 AURKB
GO:0043189	CC	H4/H2A histone acetyltransferase complex	0.285714285714286	0.487950036474267	7	4.97108061465951	RUVBL1 ACTL6A
GO:0006139	BP	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0355029585798817	0.174371271511743	3380	6.06957898635594	TAF5 RPS6KA5 TK1 STAT1 DEK PCNA TOP2A RUVBL1 SMC4 DNMT1 MYBL2 MCM5 RPA2 RRM2 MCM2 DHFR FOXM1 ACTL6A LIG1 HLTF RNASEH2A MDC1 EZH2 TMPO PTTG1 FANCG CDC6 RFC4 TRIP13 CDC45L RAD51AP1 SMC2 DBF4 RAD1 RAD54L EXO1 WDHD1 PARP2 HLF NUDT1 FEN1 CHAF1B MLF1 FST PRIM1 EXOSC9 ITGB3BP BARD1 CHEK1 BLM POLE2 GINS1 ISL1 TAF1A ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ PTTG3 CDT1 IRX5 MCM4 ASXL1 FANCI DNA2 GMPS HOXD11 EXOSC8 HMG4L ASF1B GMNN DTL SUV39H1 ORC6L TIPIN DCLRE1B E2F8 HELLS FANCE MCM10 MXD3 PUS3 PRTFDC1 NOP5/NOP58 TCF19 MND1 PCGF6 PHF19 UHRF1 GEN1 EID3 ZNF280C FIGNL1 RECQL4 KLF11 FANCM SUV39H2 PSIP1 ZNF26 PIF1 GINS2 POLA1 TOPBP1 CASP8AP2 PMS2L11 KPNA2 RRM1 MCM6 KPNA1 CSTF1 E2F1 TIMELESS CCNA2 FANCA LCMT2 TEAD4 BRCA1 ISG20 RAD51 CCNE2 PAX6 PSMC3IP LHX2 FOXD1 SP4 POU2F3 ZNF200 MCM7 RPA3 RIPK2 ZNF473 CCNE1 GMCL1 MLF1IP RPP25 DBR1 XRN2 MCM8 CDCA7 THEX1 NOM1 E2F7 IRX2 ZNF367
GO:0006260	BP	DNA replication	0.170854271356784	0.360211461280348	199	15.0288902319061	TK1 PCNA TOP2A MCM5 RPA2 RRM2 MCM2 LIG1 RNASEH2A CDC6 RFC4 CDC45L DBF4 EXO1 FEN1 CHAF1B PRIM1 BLM POLE2 GINS1 POLQ CDT1 MCM4 DNA2 GMNN DTL ORC6L TIPIN MCM10 GINS2 POLA1 PMS2L11 RRM1 MCM6 RAD51 CCNE2 MCM7 RPA3 MCM8
GO:0006261	BP	DNA-dependent DNA replication	0.180412371134021	0.362180656825698	97	11.1328548964804	PCNA MCM5 RPA2 MCM2 CDC6 RFC4 CDC45L EXO1 PRIM1 BLM CDT1 MCM4 GMNN TIPIN POLA1 PMS2L11 MCM6 RAD51 CCNE2 MCM7 MCM8
GO:0006268	BP	DNA unwinding during replication	0.25	0.398862017608733	12	5.6263793484574	MCM2 MCM4 MCM6 RAD51
GO:0006259	BP	DNA metabolic process	0.134279475982533	0.324060035186347	458	17.3210371536596	TK1 PCNA TOP2A RUVBL1 SMC4 DNMT1 MCM5 RPA2 RRM2 MCM2 LIG1 RNASEH2A MDC1 PTTG1 FANCG CDC6 RFC4 CDC45L RAD51AP1 SMC2 DBF4 RAD1 RAD54L EXO1 PARP2 NUDT1 FEN1 CHAF1B PRIM1 CHEK1 BLM POLE2 GINS1 CDKN2A POLQ PTTG3 CDT1 MCM4 FANCI DNA2 GMNN DTL ORC6L TIPIN DCLRE1B HELLS FANCE MCM10 MND1 UHRF1 GEN1 RECQL4 FANCM PIF1 GINS2 POLA1 TOPBP1 PMS2L11 KPNA2 RRM1 MCM6 KPNA1 FANCA BRCA1 ISG20 RAD51 CCNE2 PSMC3IP MCM7 RPA3 XRN2 MCM8
GO:0006281	BP	DNA repair	0.116326530612245	0.306585464494231	245	10.5613860394508	PCNA TOP2A LIG1 MDC1 PTTG1 FANCG RFC4 RAD51AP1 RAD1 RAD54L EXO1 PARP2 NUDT1 FEN1 CHAF1B CHEK1 BLM POLE2 POLQ FANCI DCLRE1B FANCE UHRF1 GEN1 RECQL4 FANCM POLA1 TOPBP1 PMS2L11 FANCA BRCA1 RAD51 RPA3
GO:0043283	BP	biopolymer metabolic process	0.0311482526589972	0.163600544085469	4607	4.9580351456995	TAF5 RPS6KA5 TK1 STAT1 DEK PCNA TOP2A RUVBL1 SMC4 DNMT1 MYBL2 MCM5 RPA2 CDC25B RRM2 MCM2 FOXM1 ACTL6A LIG1 CDC20 HLTF RNASEH2A MDC1 CDC2 EZH2 PTTG1 FANCG BUB1B VRK1 MMP9 CDC6 RFC4 TRIP13 AURKA CDC45L RAD51AP1 SMC2 DBF4 PIM2 RAD1 CDC7 RAD54L EXO1 WDHD1 PARP2 HLF NUDT1 FEN1 CHAF1B TTK MELK PLK4 FST PRIM1 EXOSC9 ITGB3BP BARD1 CHEK1 ISG15 BLM MMP3 POLE2 GINS1 ISL1 TAF1A ZNF165 HOXC6 CDKN2A HOXD10 POLQ PRSS16 PTTG3 CXCR4 CDT1 IRX5 CHEK2 MCM4 ASXL1 FANCI SENP5 DNA2 HOXD11 EXOSC8 HMG4L ASF1B GMNN DTL SUV39H1 FBXO5 ORC6L USP18 TIPIN DCLRE1B HERC5 E2F8 HELLS FANCE MCM10 MXD3 PUS3 NOP5/NOP58 UBE2T TCF19 MND1 PCGF6 PHF19 UHRF1 GEN1 MASTL KIAA1804 EID3 ZNF280C PIGX ACVR1C RECQL4 KLF11 FANCM SUV39H2 PSIP1 ZNF26 PIF1 GINS2 ZYG11A POLA1 PKN3 TOPBP1 NEDD4 CASP8AP2 PMS2L11 KPNA2 RRM1 ARAF MCM6 KPNA1 CSTF1 PLOD2 E2F1 TIMELESS FANCA LCMT2 TEAD4 BRCA1 NEK2 ISG20 RAD51 CCNE2 PAX6 PSMC3IP LHX2 FOXD1 PTP4A3 SP4 POU2F3 ZNF200 MCM7 AURKB RPA3 RIPK2 ZNF473 CCNE1 MLF1IP RPP25 DBR1 WDR5B ATG3 CDCA3 XRN2 MCM8 CDCA7 NOM1 ASB2 E2F7 IRX2 ZNF367 PPIL5
GO:0006270	BP	DNA replication initiation	0.351851851851852	0.434449581362946	27	12.2239170206236	MCM5 MCM2 CDC6 CDC45L CDT1 MCM4 TIPIN POLA1 MCM6 CCNE2 MCM7 MCM8
GO:0030174	BP	regulation of DNA replication initiation	0.5	0.534522483824849	8	9.64125704150093	CDC6 CDC45L CDT1 TIPIN
GO:0006275	BP	regulation of DNA replication	0.25	0.440958551844098	28	8.5987425174234	PCNA CDC6 CDC45L BLM CDT1 GMNN TIPIN
GO:0043226	CC	organelle	0.0308798083322241	0.163712863126588	7513	7.10874999569464	ANLN TAF5 RPS6KA5 FILIP1L BIRC5 CEP78 MPHOSPH9 TMEM22 NUSAP1 STAT1 DEK CSE1L PCNA TOP2A IFI30 RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MTHFD2 CDC25B MCM2 STCH FOXM1 ACTL6A LIG1 CDC20 HLTF RNASEH2A MDC1 SPAG5 CDC2 MTF2 EZH2 TMPO LSP1 PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH APOC1 KIF11 RAD1 BID CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 TTK CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 LAMP3 RASGRP1 CYP27B1 BLM POLE2 GINS1 ISL1 NTS KNTC1 KIF14 ABAT NUP155 TAF1A KRT31 ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PRSS16 PTTG3 HIST1H1C IFI35 KIFC1 CDT1 SPC25 ATP2C1 NCF2 TPX2 RPL39L IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B ZWILCH KIF4A DTL SUV39H1 NCAPG HJURP CENPM KIF20A NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN KIF15 C3orf52 DCLRE1B DSN1 CENPN NCAPG2 SLC15A3 STAG3 DDX25 E2F8 HELLS FANCE MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 CENPK NOP5/NOP58 SLC25A19 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 PHF19 UHRF1 SLFN11 C6orf173 C11orf82 GEN1 SGOL2 EID3 CENPH KRT80 SASS6 ZNF280C PIGX ALG10 RECQL4 KLF11 CKAP2 FANCM SUV39H2 PSIP1 ZNF26 CYP4B1 PIF1 GINS2 POLA1 CEP72 PKN3 TOPBP1 CASP8AP2 RPL30 STMN1 KPNA2 TMEM106C LPCAT1 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 PLOD2 E2F1 TIMELESS MMD CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 TIMM8A PAX6 SLC25A40 PSMC3IP KIAA1009 LHX2 FOXD1 CYP4F3 SYCP2 PTP4A3 SP4 POU2F3 ZNF200 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 SULF1 DMN ZNF473 CCNE1 TMEM48 GOLT1B COQ4 S100PBP GMCL1 KTELC1 ABHD10 MLF1IP MYO5C RPP25 DBR1 BXDC2 CENPQ FA2H CENPO NUP62CL XRN2 PARP9 MCM8 CDCA7 FAM33A NOM1 E2F7 IRX2 ZNF367
GO:0043227	CC	membrane-bound organelle	0.0319885593858197	0.166419161811444	6643	7.20939830540682	ANLN TAF5 RPS6KA5 BIRC5 MPHOSPH9 TMEM22 NUSAP1 STAT1 DEK CSE1L PCNA TOP2A IFI30 RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MTHFD2 MCM2 STCH FOXM1 ACTL6A LIG1 HLTF RNASEH2A MDC1 CDC2 MTF2 EZH2 TMPO PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH APOC1 RAD1 BID CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 LAMP3 RASGRP1 CYP27B1 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 ABAT NUP155 TAF1A ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PTTG3 HIST1H1C IFI35 KIFC1 CDT1 SPC25 ATP2C1 NCF2 TPX2 IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B KIF4A DTL SUV39H1 NCAPG HJURP CENPM KIF20A NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN C3orf52 DCLRE1B DSN1 CENPN NCAPG2 SLC15A3 STAG3 DDX25 E2F8 HELLS FANCE MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 CENPK NOP5/NOP58 SLC25A19 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 PHF19 UHRF1 SLFN11 C6orf173 C11orf82 GEN1 SGOL2 EID3 CENPH ZNF280C PIGX ALG10 RECQL4 KLF11 FANCM SUV39H2 PSIP1 ZNF26 CYP4B1 PIF1 GINS2 POLA1 PKN3 TOPBP1 CASP8AP2 KPNA2 TMEM106C LPCAT1 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 PLOD2 E2F1 TIMELESS MMD CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 TIMM8A PAX6 SLC25A40 PSMC3IP KIAA1009 LHX2 FOXD1 CYP4F3 SYCP2 PTP4A3 SP4 POU2F3 ZNF200 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 SULF1 ZNF473 CCNE1 TMEM48 GOLT1B COQ4 S100PBP GMCL1 KTELC1 ABHD10 MLF1IP RPP25 DBR1 BXDC2 CENPQ FA2H CENPO NUP62CL XRN2 PARP9 MCM8 CDCA7 NOM1 E2F7 IRX2 ZNF367
GO:0043228	CC	non-membrane-bound organelle	0.059342665855143	0.226131058976459	1643	11.2481423895305	ANLN TAF5 FILIP1L BIRC5 CEP78 NUSAP1 PCNA TOP2A SMC4 DNMT1 MYBL2 RPA2 CDC25B MCM2 CDC20 SPAG5 CDC2 TMPO LSP1 BUB1B DLG7 CDC6 RFC4 ZWINT AURKA NDC80 SMC2 NEFH KIF11 TTK CENPE PRIM1 EXOSC9 ITGB3BP MPHOSPH1 CHEK1 BLM KNTC1 KIF14 TAF1A KRT31 CDKN2A CENPF HIST1H1C KIFC1 CDT1 SPC25 TPX2 RPL39L MKI67 NCAPD3 FANCI APITD1 CCNB1 HMG4L PRC1 ASF1B ZWILCH KIF4A SUV39H1 CENPM KIF20A FBXO5 ORC6L TIPIN KIF15 DSN1 CENPN STAG3 HELLS KIF18A CDCA8 MIS12 RACGAP1 CENPK NOP5/NOP58 NUF2 CDCA5 SGOL2 CENPH KRT80 SASS6 CKAP2 SUV39H2 PIF1 POLA1 CEP72 TOPBP1 RPL30 STMN1 KIF22 H2AFV TIMELESS BRCA1 NEK2 KIF23 CENPA RAD51 KIAA1009 SYCP2 LOC81691 MCM7 KIF2C AURKB RPA3 DMN MLF1IP MYO5C CENPQ CENPO XRN2 FAM33A NOM1
GO:0043229	CC	intracellular organelle	0.0308921438082557	0.163744399428454	7510	7.11654971749136	ANLN TAF5 RPS6KA5 FILIP1L BIRC5 CEP78 MPHOSPH9 TMEM22 NUSAP1 STAT1 DEK CSE1L PCNA TOP2A IFI30 RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MTHFD2 CDC25B MCM2 STCH FOXM1 ACTL6A LIG1 CDC20 HLTF RNASEH2A MDC1 SPAG5 CDC2 MTF2 EZH2 TMPO LSP1 PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH APOC1 KIF11 RAD1 BID CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 TTK CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 LAMP3 RASGRP1 CYP27B1 BLM POLE2 GINS1 ISL1 NTS KNTC1 KIF14 ABAT NUP155 TAF1A KRT31 ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PRSS16 PTTG3 HIST1H1C IFI35 KIFC1 CDT1 SPC25 ATP2C1 NCF2 TPX2 RPL39L IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B ZWILCH KIF4A DTL SUV39H1 NCAPG HJURP CENPM KIF20A NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN KIF15 C3orf52 DCLRE1B DSN1 CENPN NCAPG2 SLC15A3 STAG3 DDX25 E2F8 HELLS FANCE MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 CENPK NOP5/NOP58 SLC25A19 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 PHF19 UHRF1 SLFN11 C6orf173 C11orf82 GEN1 SGOL2 EID3 CENPH KRT80 SASS6 ZNF280C PIGX ALG10 RECQL4 KLF11 CKAP2 FANCM SUV39H2 PSIP1 ZNF26 CYP4B1 PIF1 GINS2 POLA1 CEP72 PKN3 TOPBP1 CASP8AP2 RPL30 STMN1 KPNA2 TMEM106C LPCAT1 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 PLOD2 E2F1 TIMELESS MMD CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 TIMM8A PAX6 SLC25A40 PSMC3IP KIAA1009 LHX2 FOXD1 CYP4F3 SYCP2 PTP4A3 SP4 POU2F3 ZNF200 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 SULF1 DMN ZNF473 CCNE1 TMEM48 GOLT1B COQ4 S100PBP GMCL1 KTELC1 ABHD10 MLF1IP MYO5C RPP25 DBR1 BXDC2 CENPQ FA2H CENPO NUP62CL XRN2 PARP9 MCM8 CDCA7 FAM33A NOM1 E2F7 IRX2 ZNF367
GO:0043231	CC	intracellular membrane-bound organelle	0.0319981930432164	0.166443296894383	6641	7.214869515696	ANLN TAF5 RPS6KA5 BIRC5 MPHOSPH9 TMEM22 NUSAP1 STAT1 DEK CSE1L PCNA TOP2A IFI30 RUVBL1 INSIG1 SMC4 DNMT1 MYBL2 MCM5 RPA2 MTHFD2 MCM2 STCH FOXM1 ACTL6A LIG1 HLTF RNASEH2A MDC1 CDC2 MTF2 EZH2 TMPO PTTG1 FANCG BUB1B DLG7 VRK1 CDC6 RFC4 ZWINT TRIP13 TOE1 AURKA CDC45L RAD51AP1 NDC80 SMC2 DBF4 S100P NEFH APOC1 RAD1 BID CDC7 RAD54L EXO1 WDHD1 PARP2 HLF FEN1 CHAF1B MLF1 CENPE PRIM1 EXOSC9 ITGB3BP CA9 MPHOSPH1 BARD1 CHEK1 LAMP3 RASGRP1 CYP27B1 BLM POLE2 GINS1 ISL1 KNTC1 KIF14 ABAT NUP155 TAF1A ZNF165 HOXC6 CDKN2A CENPF HOXD10 POLQ ANP32E PTTG3 HIST1H1C IFI35 KIFC1 CDT1 SPC25 ATP2C1 NCF2 TPX2 IRX5 CHEK2 MKI67 MCM4 ASXL1 NUP210 NCAPD3 NCAPH FANCI SENP5 APITD1 HOXD11 CCNB1 EXOSC8 HMG4L PRC1 ASF1B KIF4A DTL SUV39H1 NCAPG HJURP CENPM KIF20A NUP107 FBXO5 RMI1 ORC6L USP18 TIPIN C3orf52 DCLRE1B DSN1 CENPN NCAPG2 SLC15A3 STAG3 DDX25 E2F8 HELLS FANCE MCM10 MXD3 KIF18A PUS3 CDCA8 MIS12 DONSON RACGAP1 CENPK NOP5/NOP58 SLC25A19 TCF19 NUF2 ZIC2 MND1 PCGF6 BEX2 CDCA5 C15orf23 PHF19 UHRF1 SLFN11 C6orf173 C11orf82 GEN1 SGOL2 EID3 CENPH ZNF280C PIGX ALG10 RECQL4 KLF11 FANCM SUV39H2 PSIP1 ZNF26 CYP4B1 PIF1 GINS2 POLA1 PKN3 TOPBP1 CASP8AP2 KPNA2 TMEM106C LPCAT1 MCM6 KPNA1 KIF22 CSTF1 STAG1 H2AFV KIAA0101 PLOD2 E2F1 TIMELESS MMD CCNA2 FANCA CDKN2C TEAD4 BRCA1 NEK2 ISG20 KIF23 CENPA RAD51 CCNE2 TIMM8A PAX6 SLC25A40 PSMC3IP KIAA1009 LHX2 FOXD1 CYP4F3 SYCP2 PTP4A3 SP4 POU2F3 ZNF200 CYP7B1 LOC81691 MCM7 KIF2C AURKB RPA3 EED NUP205 SULF1 ZNF473 CCNE1 TMEM48 GOLT1B COQ4 S100PBP GMCL1 KTELC1 ABHD10 MLF1IP RPP25 DBR1 BXDC2 CENPQ FA2H CENPO NUP62CL XRN2 PARP9 MCM8 CDCA7 NOM1 E2F7 IRX2 ZNF367
GO:0043232	CC	intracellular non-membrane-bound organelle	0.059342665855143	0.226131058976459	1643	11.2481423895305	ANLN TAF5 FILIP1L BIRC5 CEP78 NUSAP1 PCNA TOP2A SMC4 DNMT1 MYBL2 RPA2 CDC25B MCM2 CDC20 SPAG5 CDC2 TMPO LSP1 BUB1B DLG7 CDC6 RFC4 ZWINT AURKA NDC80 SMC2 NEFH KIF11 TTK CENPE PRIM1 EXOSC9 ITGB3BP MPHOSPH1 CHEK1 BLM KNTC1 KIF14 TAF1A KRT31 CDKN2A CENPF HIST1H1C KIFC1 CDT1 SPC25 TPX2 RPL39L MKI67 NCAPD3 FANCI APITD1 CCNB1 HMG4L PRC1 ASF1B ZWILCH KIF4A SUV39H1 CENPM KIF20A FBXO5 ORC6L TIPIN KIF15 DSN1 CENPN STAG3 HELLS KIF18A CDCA8 MIS12 RACGAP1 CENPK NOP5/NOP58 NUF2 CDCA5 SGOL2 CENPH KRT80 SASS6 CKAP2 SUV39H2 PIF1 POLA1 CEP72 TOPBP1 RPL30 STMN1 KIF22 H2AFV TIMELESS BRCA1 NEK2 KIF23 CENPA RAD51 KIAA1009 SYCP2 LOC81691 MCM7 KIF2C AURKB RPA3 DMN MLF1IP MYO5C CENPQ CENPO XRN2 FAM33A NOM1
GO:0043234	CC	protein complex	0.0386612810155799	0.183640523579812	1733	5.08114147765146	TAF5 FILIP1L BIRC5 CSE1L PCNA TOP2A ENO2 RUVBL1 SMC4 RPA2 MCM2 ACTL6A C1QB MDC1 EZH2 BUB1B RFC4 ZWINT SMC2 NEFH KIF11 CHAF1B CENPE PRIM1 EXOSC9 MPHOSPH1 BARD1 PLA2G7 MICB KIF14 ABAT NUP155 TAF1A CENPF HIST1H1C KIFC1 NUP210 NCAPD3 EXOSC8 ZWILCH KIF4A KIF20A NUP107 ORC6L KIF15 DSN1 E2F8 KIF18A CDCA8 MIS12 ZIC2 PCGF6 CDCA5 SGOL2 CENPH ACVR1C OSMR POLA1 KPNA2 RRM1 KPNA1 KIF22 H2AFV E2F1 BRCA1 KIF23 CENPA NCF4 TIMM8A MCM7 KIF2C RPA3 EED NUP205 TMEM48 MYO5C ATG3 NUP62CL E2F7
GO:0051276	BP	chromosome organization and biogenesis	0.105113636363636	0.300098727603511	352	11.1842782853008	TAF5 RPS6KA5 NUSAP1 TOP2A RUVBL1 SMC4 MCM2 ACTL6A HLTF EZH2 PTTG1 DLG7 ZWINT NDC80 SMC2 NEFH CHAF1B CENPE BLM CENPF PTTG3 HIST1H1C KIFC1 NCAPD3 NCAPH ASF1B SUV39H1 NCAPG NCAPG2 STAG3 HELLS MIS12 CDCA5 CENPH RECQL4 SUV39H2 PIF1 H2AFV CENPA SYCP2
GO:0030261	BP	chromosome condensation	0.45	0.51041778553404	20	13.6530020930671	NUSAP1 TOP2A SMC4 SMC2 NCAPD3 NCAPH NCAPG NCAPG2 CDCA5
GO:0008408	MF	3'-5' exonuclease activity	0.173913043478261	0.357029908734864	23	5.18586946857181	RAD1 EXOSC9 EXOSC8 ISG20 THEX1
GO:0008409	MF	5'-3' exonuclease activity	0.625	0.478713553878169	4	8.60102858247011	EXO1 FEN1 XRN2
GO:0008156	BP	negative regulation of DNA replication	0.352941176470588	0.492592183071889	17	9.7286167772395	CDC6 CDC45L BLM CDT1 GMNN TIPIN
GO:0022402	BP	cell cycle process	0.182151589242054	0.367755868648162	409	23.3423625701594	ANLN CDKN3 BIRC5 MPHOSPH9 NUSAP1 RUVBL1 SMC4 CDC25B CDC20 SPAG5 CDC2 PTTG1 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 CKS2 SMC2 DBF4 PIM2 KIF11 RAD1 CDC7 RAD54L EXO1 MLF1 TTK CENPE MPHOSPH1 BARD1 CHEK1 BLM KNTC1 CDKN2A CENPF KIFC1 CDT1 SPC25 TPX2 NCAPD3 NCAPH CCNB1 PRC1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 STAG3 HELLS CDCA8 MIS12 RACGAP1 NUF2 MND1 CDCA5 C11orf82 SASS6 RECQL4 POLA1 STMN1 KPNA2 KIF22 STAG1 E2F1 TIMELESS CCNA2 CDKN2C BRCA1 NEK2 KIF23 RAD51 PSMC3IP KIAA1009 SYCP2 KIF2C AURKB CCNE1 RBM7 CDCA3 FAM33A
GO:0022403	BP	cell cycle phase	0.198795180722892	0.380330267006024	332	23.1660629999681	ANLN CDKN3 BIRC5 MPHOSPH9 NUSAP1 RUVBL1 SMC4 CDC25B CDC20 SPAG5 CDC2 PTTG1 BUB1B DLG7 CDC6 ZWINT AURKA NDC80 CKS2 SMC2 DBF4 PIM2 KIF11 RAD1 CDC7 RAD54L EXO1 CENPE MPHOSPH1 CHEK1 BLM KNTC1 CDKN2A CENPF KIFC1 CDT1 SPC25 TPX2 NCAPD3 NCAPH CCNB1 ZWILCH CEP55 NCAPG FBXO5 TIPIN KIF15 DSN1 NCAPG2 STAG3 HELLS CDCA8 MIS12 NUF2 MND1 CDCA5 POLA1 KPNA2 KIF22 STAG1 E2F1 TIMELESS CCNA2 CDKN2C NEK2 KIF23 RAD51 PSMC3IP KIAA1009 SYCP2 KIF2C AURKB CCNE1 RBM7 CDCA3 FAM33A
GO:0016020	CC	membrane	0.0127610208816705	0.105002822842649	6034	-6.85128651944641	PIGX ALG10 ACVR1C OSMR CYP4B1 POLA1 CNTLN KPNA2 TMEM106C LPCAT1 KPNA1 PLSCR1 PLOD2 MMD TMEFF1 NCF4 CELSR3 TIMM8A IL1RAP CD38 SLC25A40 CYP4F3 PTP4A3 CYP7B1 P2RY1 NUP205 TMEM194 FPRL2 TMEM48 GOLT1B FLRT3 SLAMF8 FA2H NUP62CL AADACL1 TMEM68 TRIM59 DPY19L2 HS6ST2 KIAA1524 CLEC2B SLC16A1 MPHOSPH9 TMEM22 CSE1L PCNA ENO2 RUVBL1 INSIG1 CD14 ACTL6A RGS1 MDC1 TMPO LSP1 CD163 BID SELL CCR1 CA9 KIAA0133 LAMP3 RASGRP1 LY75 CYP27B1 SYNGR3 ADAMDEC1 SELE MICB NUP155 LY96 GPR19 CENPF CXCR4 ATP2C1 TMEM97 NUP210 PAQR4 LPPR4 SLC38A6 FAM69A NUP107 NETO2 CKLF C3orf52 SLC15A3 TMEM180 FICD SLC25A19 TNFSF13B ZIC2 ZDHHC23 C1orf162 ALG10B GBP5 TMEM71
GO:0016021	CC	integral to membrane	0.0129972875226040	0.105257085406937	4424	-5.31103420227124	PIGX ALG10 ACVR1C OSMR KPNA2 TMEM106C LPCAT1 KPNA1 PLSCR1 MMD TMEFF1 NCF4 CELSR3 IL1RAP CD38 SLC25A40 CYP4F3 P2RY1 NUP205 TMEM194 FPRL2 TMEM48 GOLT1B FLRT3 SLAMF8 FA2H NUP62CL AADACL1 TMEM68 TRIM59 DPY19L2 HS6ST2 KIAA1524 CLEC2B SLC16A1 TMEM22 CSE1L INSIG1 TMPO CD163 SELL CCR1 CA9 KIAA0133 LAMP3 LY75 SYNGR3 ADAMDEC1 SELE NUP155 GPR19 CXCR4 ATP2C1 TMEM97 NUP210 PAQR4 LPPR4 SLC38A6 FAM69A NUP107 NETO2 CKLF C3orf52 SLC15A3 TMEM180 FICD SLC25A19 TNFSF13B ZIC2 ZDHHC23 C1orf162 ALG10B TMEM71
GO:0051726	BP	regulation of cell cycle	0.117437722419929	0.314100502342701	281	11.4578175643716	ANLN CDKN3 BIRC5 NUSAP1 CKS1B CDC2 FANCG BUB1B DLG7 CDC6 ZWINT CDC45L CKS2 RAD1 CDC7 TTK MPHOSPH1 CHEK1 BLM KNTC1 CDKN2A CENPF CDT1 CHEK2 ZWILCH GMNN FBXO5 TIPIN HERC5 CABLES2 TIMELESS CCNA2 CDKN2C BRCA1 NEK2 CCNE2
GO:0016043	BP	cellular component organization and biogenesis	0.0367488110678772	0.181158745145173	2313	5.2835395326833	ANLN TAF5 RPS6KA5 BIRC5 NUSAP1 STAT1 CSE1L PCNA TOP2A RUVBL1 SMC4 CD14 MCM2 ACTL6A HLTF SPAG5 EZH2 PTTG1 BUB1B DLG7 MMP9 ZWINT AURKA NDC80 CKS2 SMC2 PIM2 NEFH KIF11 BID CHAF1B TTK CENPE EXOSC9 MPHOSPH1 BARD1 LY75 BLM KNTC1 KIF14 NUP155 CDKN2A CENPF PTTG3 CXCR4 HIST1H1C KIFC1 ATP2C1 NUP210 NCAPD3 NCAPH EXOSC8 PRC1 ASF1B KIF4A SUV39H1 NCAPG KIF20A NUP107 CKLF KIF15 NCAPG2 STAG3 DDX25 HELLS KIF18A MIS12 RACGAP1 NOP5/NOP58 TNFSF13B CDCA5 CENPH SASS6 RECQL4 SUV39H2 PIF1 STMN1 KPNA2 KPNA1 KIF22 PLSCR1 H2AFV FANCA BRCA1 KIF23 CENPA RAD51 TIMM8A IL1RAP PAX6 SYCP2 KIF2C NUP205 TMEM48 BXDC2 COL8A2 XRN2
GO:0035267	CC	NuA4 histone acetyltransferase complex	0.333333333333333	0.516397779494322	6	5.43481989678624	RUVBL1 ACTL6A