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Methods in Heritability Estimation

 

 

Main Methods:

 

 

  1. Selection Experiment

     

    please refer to the example of last page

     

  2. Comparison of close relatives

     

     

  3. Parent-Offspring regression

     

    heregre

    This is an example of different regression lines(slopes) representing different level of heretability. The slpe of the line approximates the heritability of the trait when offspring values are regressed against the average trait value in the parents.

     

  4. Twin Studies

     

    H2=2(r(MZ)-r(DZ)). Where DZ indicates fraternal twins(they share half of their genes), MZ indicates identical twins, r is correlation.

     

  5. Sibling Comparison

     

    Full sibling desing: Comparing similarity between siblings who share both a biological mother and a father.

    Half sibling desing: Comparing similarity between siblings who share one parents with the other sibling group.

     

  6. Analysis of Variance